Editorial: Mitochondrial OXPHOS System: Emerging Concepts and Technologies and Role in Disease.

Mitochondria are eukaryotic organelles responsible for generating the main bulk of ATP, the cellular energy currency, via the process of oxidative phosphorylation (OXPHOS). The OXPHOS system is unique because it comprises subunits of dual genetic origin, encoded in the mitochondrial and the nuclear...

Descripción completa

Detalles Bibliográficos
Autores: Fernández Vizarra, Erika, Callegari, Sylvie, Garrabou Tornos, Glòria, Pacheu Grau, David
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2022
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/209383
Acceso en línea:https://hdl.handle.net/2445/209383
Access Level:acceso abierto
Palabra clave:Mitocondris
Proteòmica
Control de qualitat
Genomes
Mitochondria
Proteomics
Quality control
Descripción
Sumario:Mitochondria are eukaryotic organelles responsible for generating the main bulk of ATP, the cellular energy currency, via the process of oxidative phosphorylation (OXPHOS). The OXPHOS system is unique because it comprises subunits of dual genetic origin, encoded in the mitochondrial and the nuclear genomes. Therefore, to form the multimeric membrane-bound complexes responsible for this energy production process, proteins translated inside the organelle must be assembled in coordination with those expressed in the cytosol and imported into mitochondria by using a sophisticated import and translocation machinery