Pre-emptive TIPS should be considered in high-risk patients with both acute variceal bleeding and severe alcohol-related hepatitis

[Background & Aims] Severe alcohol-related hepatitis (AH) and acute variceal bleeding (AVB) may occur simultaneously. The impact of a pre-emptive transjugular intrahepatic portosystemic shunt (pTIPS) in high-risk patients (patients with Child–Pugh (CP) B and active bleeding or CP C10–13 cirrhosi...

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Detalhes bibliográficos
Autores: Rudler, Marika, Hernández Gea, Virginia, Larrue, Hélène, Bouzbib, Charlotte, Procopet, Bogdan, Baiges, Anna, Turon, Fanny, Villanueva, Cándido, Albillos, Agustín, Alvarado-Tapias, Edilmar, Gluud, Lise L., Praktiknjo, Michael, Genesca, Joan, Ventura-Cots, Meritxell, Villagrasa, Ares, Rodrigues, Susanna, Mouri, Sarah, Giráldez-Gallego, Álvaro, Masnou Ridaura, Helena, Laleman, Wim, Bureau, Christophe, Robic, Marie-Angèle, Hartl, Lukas, Tellez, Luis, Zipprich, Alexander, Canete, Nuria, Sultanik, Philippe, Deckmyn, Olivier, Mandorfer, Mattias, Senzolo, Marco, Schepis, Filippo, Tripathi, Dhiraj, García-Pagán, Joan Carles, Thabut, Dominique
Tipo de documento: artigo
Estado:Versão publicada
Data de publicação:2025
País:España
Recursos:Consejo Superior de Investigaciones Científicas (CSIC)
Repositório:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/413092
Acesso em linha:http://hdl.handle.net/10261/413092
https://api.elsevier.com/content/abstract/scopus_id/105022182563
Access Level:Acceso aberto
Palavra-chave:Acute variceal bleeding
Cirrhosis
Portal hypertension
Severe alcohol-related hepatitis
TIPS
Descrição
Resumo:[Background & Aims] Severe alcohol-related hepatitis (AH) and acute variceal bleeding (AVB) may occur simultaneously. The impact of a pre-emptive transjugular intrahepatic portosystemic shunt (pTIPS) in high-risk patients (patients with Child–Pugh (CP) B and active bleeding or CP C10–13 cirrhosis) with AVB and concomitant severe AH is unknown. The objective of the study was to compare the outcomes of severe AH in patients with high-risk AVB treated with pTIPS or endoscopic and drug treatment (Endo+drugs).