Wireless Electrical-Molecular Quantum Signalling for Cancer Cell Induced Death
<p>Quantum biological electron tunnelling (QBET) underpins cellular behaviour. Control of</p><p>electrical-molecular communication could revolutionise the development of disruptive</p><p>technologies for understanding and modulating molecular signalling. Current communi...
| Autores: | , , , , , , , , , , , , |
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| Tipo de recurso: | artículo |
| Fecha de publicación: | 2023 |
| País: | España |
| Institución: | Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya) |
| Repositorio: | Recercat. Dipósit de la Recerca de Catalunya |
| OAI Identifier: | oai:recercat.cat:2445/208253 |
| Acceso en línea: | http://hdl.handle.net/2445/208253 |
| Access Level: | acceso abierto |
| Palabra clave: | Nanotecnologia Electroquímica Bioelectrònica Nanotechnology Electrochemistry Bioelectronics |
| Sumario: | <p>Quantum biological electron tunnelling (QBET) underpins cellular behaviour. Control of</p><p>electrical-molecular communication could revolutionise the development of disruptive</p><p>technologies for understanding and modulating molecular signalling. Current communication</p><p>technology is not appropriate for interfacing with cells at a spatial/temporal level equivalent to</p><p>the native biological signalling. We merge bipolar nano-electrochemical tools with cancer</p><p>cells. Gold-bipolar nanoelectrodes functionalised with electron acceptor-donor-species, were</p><p>developed as electric field bio-actuators we term bio-nanoantennae. Remote electrical input</p><p>regulated electron transport between the acceptor-donor species at the bio-nanoantennae in a</p><p>selective manner. The wireless modulation of electron transport results in QBET triggering</p><p>apoptosis in patient-derived cancer cells representing electrical-molecular communication.</p><p>Transcriptomics data highlight the electric field targets the cancer cells in a unique manner.</p><p>The stated insight and invention open a plethora of applications in healthcare. This may lead</p><p>to new quantum-based medical diagnostics and treatments, as well as understanding of the</p><p>biological physics.</p> |
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