New organocatalyzed transformations of aziridines

Aziridines are among the most versatile intermediates in organic synthesis. A number of biologically significant molecules contain these strained threemembered rings within their structures. Consequently, there is currently a growing interest of the synthetic community in selective transformations o...

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Detalles Bibliográficos
Autor: Díaz de los Bernardos Sánchez, Miriam
Tipo de recurso: tesis doctoral
Estado:Versión publicada
Fecha de publicación:2013
País:España
Institución:Universitat Rovira i virgili (URV)
Repositorio:Repositori Institucional de la Universitat Rovira i Virgili
OAI Identifier:oai:urv.cat:TDX:1428
Acceso en línea:https://hdl.handle.net/20.500.11797/TDX1428
http://hdl.handle.net/10803/284090
Access Level:acceso abierto
Palabra clave:547 - Química orgànica
54 - Química
Descripción
Sumario:Aziridines are among the most versatile intermediates in organic synthesis. A number of biologically significant molecules contain these strained threemembered rings within their structures. Consequently, there is currently a growing interest of the synthetic community in selective transformations of aziridines. This thesis aims at the development of new synthetic strategies for efficient aziridine transformations using selective catalysis based on small organic molecules. Thus, new organocatalytic procedures in aziridine ring-opening chemistry, focusing on the development of efficient synthetic applications of these versatile intermediates were envisioned.