Overeating, caloric restriction and mammographic density in Spanish women. DDM-Spain study

Objectives: Mammographic density (MD) is a strong risk factor for breast cancer. The present study evaluates the association between relative caloric intake and MD in Spanish women. Study design: We conducted a cross-sectional study in which 3517 women were recruited from seven breast cancer screeni...

Descripción completa

Detalles Bibliográficos
Autores: del Pozo, Maria del Pilar, Castelló Pastor, Adela, Vidal, Carmen, Salas-Trejo, Dolores, Sanchez-Contador Escudero, Carmen, Pedraz-Pingarrón, Carmen, Moreo, Pilar, Santamarina, Carmen, Ederra, María, Llobet, Rafael, Vioque, Jesus, Perez-Gomez, Beatriz, Pollan-Santamaria, Marina, Lope Carvajal, Virginia
Tipo de recurso: artículo
Fecha de publicación:2018
País:España
Institución:Instituto de Salud Carlos III (ISCIII)
Repositorio:Repisalud
Idioma:inglés
OAI Identifier:oai:repisalud.isciii.es:20.500.12105/22639
Acceso en línea:https://hdl.handle.net/20.500.12105/22639
Access Level:acceso abierto
Palabra clave:Breast density
Calories
Energy intake
Caloric intake
Basal metabolic rate
Hiperfagia
Densidad de la Mama
Factores de Riesgo
Humanos
Persona de Mediana Edad
Oportunidad Relativa
Ingestión de Energía
Mamografía
Femenino
Detección Precoz del Cáncer
España
Early Detection of Cancer
Energy Intake
Spain
Female
Risk Factors
Humans
Odds Ratio
Hyperphagia
Mammography
Breast Density
Middle Aged
id ES_bd78d31ced8cdfd3364435eb93ef60a5
oai_identifier_str oai:repisalud.isciii.es:20.500.12105/22639
network_acronym_str ES
network_name_str España
repository_id_str
spelling Overeating, caloric restriction and mammographic density in Spanish women. DDM-Spain studydel Pozo, Maria del PilarCastelló Pastor, AdelaVidal, CarmenSalas-Trejo, DoloresSanchez-Contador Escudero, CarmenPedraz-Pingarrón, CarmenMoreo, PilarSantamarina, CarmenEderra, MaríaLlobet, RafaelVioque, JesusPerez-Gomez, BeatrizPollan-Santamaria, MarinaLope Carvajal, VirginiaBreast densityCaloriesEnergy intakeCaloric intakeBasal metabolic rateHiperfagiaDensidad de la MamaFactores de RiesgoHumanosPersona de Mediana EdadOportunidad RelativaIngestión de EnergíaMamografíaFemeninoDetección Precoz del CáncerEspañaEarly Detection of CancerEnergy IntakeSpainFemaleRisk FactorsHumansOdds RatioHyperphagiaMammographyBreast DensityMiddle AgedObjectives: Mammographic density (MD) is a strong risk factor for breast cancer. The present study evaluates the association between relative caloric intake and MD in Spanish women. Study design: We conducted a cross-sectional study in which 3517 women were recruited from seven breast cancer screening centers. MD was measured by an experienced radiologist using craniocaudal mammography and Boyd's semi-quantitative scale. Information was collected through an epidemiological survey. Predicted calories were calculated using linear regression models, including the basal metabolic rate and physical activity as explanatory variables. Overeating and caloric restriction were defined taking into account the 99% confidence interval of the predicted value. Odds ratios (OR) and 95% confidence intervals (95%CI) were estimated using center-specific mixed ordinal logistic regression models, adjusted for age, menopausal status, body mass index, parity, tobacco use, family history of breast cancer, previous biopsies, age at menarche and adherence to a Western diet. Main outcome measure: Mammographic density. Results: Those women with an excessive caloric intake ( > 40% above predicted) presented higher MD (OR = 1.41, 95%CI = 0.97-2.03; p = 0.070). For every 20% increase in relative caloric consumption the probability of having higher MD increased by 5% (OR = 1.05, 95%CI = 0.98-1.14; p = 0.178), not observing differences between the categories of explanatory variables. Caloric restriction was not associated with MD in our study. Conclusions: This is the first study exploring the association between MD and the effect of caloric deficit or excessive caloric consumption according to the energy requirements of each woman. Although caloric restriction does not seem to affect breast density, a caloric intake above predicted levels seems to increase this phenotype.Elsevier20242024-09-0620182018-11-0120182018-11-01research articlehttp://purl.org/coar/resource_type/c_2df8fbb1SMURhttp://purl.org/coar/version/c_71e4c1898caa6e32info:eu-repo/semantics/articlehttps://hdl.handle.net/20.500.12105/22639reponame:Repisaludinstname:Instituto de Salud Carlos III (ISCIII)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2Attribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:repisalud.isciii.es:20.500.12105/226392026-06-12T12:43:37Z
dc.title.none.fl_str_mv Overeating, caloric restriction and mammographic density in Spanish women. DDM-Spain study
title Overeating, caloric restriction and mammographic density in Spanish women. DDM-Spain study
spellingShingle Overeating, caloric restriction and mammographic density in Spanish women. DDM-Spain study
del Pozo, Maria del Pilar
Breast density
Calories
Energy intake
Caloric intake
Basal metabolic rate
Hiperfagia
Densidad de la Mama
Factores de Riesgo
Humanos
Persona de Mediana Edad
Oportunidad Relativa
Ingestión de Energía
Mamografía
Femenino
Detección Precoz del Cáncer
España
Early Detection of Cancer
Energy Intake
Spain
Female
Risk Factors
Humans
Odds Ratio
Hyperphagia
Mammography
Breast Density
Middle Aged
title_short Overeating, caloric restriction and mammographic density in Spanish women. DDM-Spain study
title_full Overeating, caloric restriction and mammographic density in Spanish women. DDM-Spain study
title_fullStr Overeating, caloric restriction and mammographic density in Spanish women. DDM-Spain study
title_full_unstemmed Overeating, caloric restriction and mammographic density in Spanish women. DDM-Spain study
title_sort Overeating, caloric restriction and mammographic density in Spanish women. DDM-Spain study
dc.creator.none.fl_str_mv del Pozo, Maria del Pilar
Castelló Pastor, Adela
Vidal, Carmen
Salas-Trejo, Dolores
Sanchez-Contador Escudero, Carmen
Pedraz-Pingarrón, Carmen
Moreo, Pilar
Santamarina, Carmen
Ederra, María
Llobet, Rafael
Vioque, Jesus
Perez-Gomez, Beatriz
Pollan-Santamaria, Marina
Lope Carvajal, Virginia
author del Pozo, Maria del Pilar
author_facet del Pozo, Maria del Pilar
Castelló Pastor, Adela
Vidal, Carmen
Salas-Trejo, Dolores
Sanchez-Contador Escudero, Carmen
Pedraz-Pingarrón, Carmen
Moreo, Pilar
Santamarina, Carmen
Ederra, María
Llobet, Rafael
Vioque, Jesus
Perez-Gomez, Beatriz
Pollan-Santamaria, Marina
Lope Carvajal, Virginia
author_role author
author2 Castelló Pastor, Adela
Vidal, Carmen
Salas-Trejo, Dolores
Sanchez-Contador Escudero, Carmen
Pedraz-Pingarrón, Carmen
Moreo, Pilar
Santamarina, Carmen
Ederra, María
Llobet, Rafael
Vioque, Jesus
Perez-Gomez, Beatriz
Pollan-Santamaria, Marina
Lope Carvajal, Virginia
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv
dc.subject.none.fl_str_mv Breast density
Calories
Energy intake
Caloric intake
Basal metabolic rate
Hiperfagia
Densidad de la Mama
Factores de Riesgo
Humanos
Persona de Mediana Edad
Oportunidad Relativa
Ingestión de Energía
Mamografía
Femenino
Detección Precoz del Cáncer
España
Early Detection of Cancer
Energy Intake
Spain
Female
Risk Factors
Humans
Odds Ratio
Hyperphagia
Mammography
Breast Density
Middle Aged
topic Breast density
Calories
Energy intake
Caloric intake
Basal metabolic rate
Hiperfagia
Densidad de la Mama
Factores de Riesgo
Humanos
Persona de Mediana Edad
Oportunidad Relativa
Ingestión de Energía
Mamografía
Femenino
Detección Precoz del Cáncer
España
Early Detection of Cancer
Energy Intake
Spain
Female
Risk Factors
Humans
Odds Ratio
Hyperphagia
Mammography
Breast Density
Middle Aged
description Objectives: Mammographic density (MD) is a strong risk factor for breast cancer. The present study evaluates the association between relative caloric intake and MD in Spanish women. Study design: We conducted a cross-sectional study in which 3517 women were recruited from seven breast cancer screening centers. MD was measured by an experienced radiologist using craniocaudal mammography and Boyd's semi-quantitative scale. Information was collected through an epidemiological survey. Predicted calories were calculated using linear regression models, including the basal metabolic rate and physical activity as explanatory variables. Overeating and caloric restriction were defined taking into account the 99% confidence interval of the predicted value. Odds ratios (OR) and 95% confidence intervals (95%CI) were estimated using center-specific mixed ordinal logistic regression models, adjusted for age, menopausal status, body mass index, parity, tobacco use, family history of breast cancer, previous biopsies, age at menarche and adherence to a Western diet. Main outcome measure: Mammographic density. Results: Those women with an excessive caloric intake ( > 40% above predicted) presented higher MD (OR = 1.41, 95%CI = 0.97-2.03; p = 0.070). For every 20% increase in relative caloric consumption the probability of having higher MD increased by 5% (OR = 1.05, 95%CI = 0.98-1.14; p = 0.178), not observing differences between the categories of explanatory variables. Caloric restriction was not associated with MD in our study. Conclusions: This is the first study exploring the association between MD and the effect of caloric deficit or excessive caloric consumption according to the energy requirements of each woman. Although caloric restriction does not seem to affect breast density, a caloric intake above predicted levels seems to increase this phenotype.
publishDate 2018
dc.date.none.fl_str_mv 2018
2018-11-01
2018
2018-11-01
2024
2024-09-06
dc.type.none.fl_str_mv research article
http://purl.org/coar/resource_type/c_2df8fbb1
SMUR
http://purl.org/coar/version/c_71e4c1898caa6e32
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://hdl.handle.net/20.500.12105/22639
url https://hdl.handle.net/20.500.12105/22639
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repisalud
instname:Instituto de Salud Carlos III (ISCIII)
instname_str Instituto de Salud Carlos III (ISCIII)
reponame_str Repisalud
collection Repisalud
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869418203022622720
score 15.811543

Similares en LA Referencia