A new technique for feeding dogs with a congenital cleft palate for surgical research

In humans, cleft palate (CP) is one of the most common malformations. Although surgeons use palatoplasty to close CP defects in children, its consequences for subsequent facial growth have prompted investigations into other novel surgical alternatives. The animal models of CP used to evaluate new su...

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Autores: López-Gordillo, Yamila et al., González-Meli, B, Martínez Sanz, Elena, Casado Gómez, Inmaculada, Martín Álvaro, María Concepción, González Aranda, Pablo, Paradas Lara, Irene, Maldonado Bautista, Estela, Maestro De Las Casas, María Del Carmen, Prados Frutos, Juan Carlos, Martínez Álvarez, María Concepción
Tipo de recurso: artículo
Fecha de publicación:2011
País:España
Institución:Universidad Complutense de Madrid (UCM)
Repositorio:Docta Complutense
Idioma:inglés
OAI Identifier:oai:docta.ucm.es:20.500.14352/101441
Acceso en línea:https://hdl.handle.net/20.500.14352/101441
Access Level:acceso abierto
Palabra clave:61
Cleft palate
Dog
Refinement
Feeding technique
Ciencias Biomédicas
24 Ciencias de la Vida
32 Ciencias Médicas
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repository_id_str
spelling A new technique for feeding dogs with a congenital cleft palate for surgical researchLópez-Gordillo, Yamila et al.González-Meli, BMartínez Sanz, ElenaCasado Gómez, InmaculadaMartín Álvaro, María ConcepciónGonzález Aranda, PabloParadas Lara, IreneMaldonado Bautista, EstelaMaestro De Las Casas, María Del CarmenPrados Frutos, Juan CarlosMartínez Álvarez, María Concepción61Cleft palateDogRefinementFeeding techniqueCiencias Biomédicas24 Ciencias de la Vida32 Ciencias MédicasIn humans, cleft palate (CP) is one of the most common malformations. Although surgeons use palatoplasty to close CP defects in children, its consequences for subsequent facial growth have prompted investigations into other novel surgical alternatives. The animal models of CP used to evaluate new surgical treatments are frequently obtained by creating surgically induced clefts in adult dogs. This procedure has been ethically criticized due to its severity and questionable value as an animal model for human CP. Dogs born with a congenital CP would be much better for this purpose, provided they developed CP at a sufficient rate and could be fed. Up until now, feeding these pups carried the risk of aspiration pneumonia, while impeding normal suckling and chewing, and thus compromising orofacial growth. We developed a technique for feeding dog pups with CP from birth to the time of surgery using two old Spanish pointer dog pups bearing a complete CP. This dog strain develops CP in 15-20% of the offspring spontaneously. Custom-made feeding teats and palatal prostheses adapted to the pups' palates were made from thermoplastic plates. This feeding technique allowed lactation, eating and drinking in the pups with CP, with only sporadic rhinitis. To determine whether the use of this palatal prosthesis interferes with palatal growth, the palates of three littermate German shorthaired pointer pups without CP, either wearing or not wearing (controls) the prosthesis, were measured. The results showed that the permanent use of this prosthesis does not impede palatal growth in the pups.SAGE PublicationsUniversidad Complutense de Madrid20112011-01-0120112011-01-01journal articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/20.500.14352/101441reponame:Docta Complutenseinstname:Universidad Complutense de Madrid (UCM)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2Attribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:docta.ucm.es:20.500.14352/1014412026-06-02T12:44:21Z
dc.title.none.fl_str_mv A new technique for feeding dogs with a congenital cleft palate for surgical research
title A new technique for feeding dogs with a congenital cleft palate for surgical research
spellingShingle A new technique for feeding dogs with a congenital cleft palate for surgical research
López-Gordillo, Yamila et al.
61
Cleft palate
Dog
Refinement
Feeding technique
Ciencias Biomédicas
24 Ciencias de la Vida
32 Ciencias Médicas
title_short A new technique for feeding dogs with a congenital cleft palate for surgical research
title_full A new technique for feeding dogs with a congenital cleft palate for surgical research
title_fullStr A new technique for feeding dogs with a congenital cleft palate for surgical research
title_full_unstemmed A new technique for feeding dogs with a congenital cleft palate for surgical research
title_sort A new technique for feeding dogs with a congenital cleft palate for surgical research
dc.creator.none.fl_str_mv López-Gordillo, Yamila et al.
González-Meli, B
Martínez Sanz, Elena
Casado Gómez, Inmaculada
Martín Álvaro, María Concepción
González Aranda, Pablo
Paradas Lara, Irene
Maldonado Bautista, Estela
Maestro De Las Casas, María Del Carmen
Prados Frutos, Juan Carlos
Martínez Álvarez, María Concepción
author López-Gordillo, Yamila et al.
author_facet López-Gordillo, Yamila et al.
González-Meli, B
Martínez Sanz, Elena
Casado Gómez, Inmaculada
Martín Álvaro, María Concepción
González Aranda, Pablo
Paradas Lara, Irene
Maldonado Bautista, Estela
Maestro De Las Casas, María Del Carmen
Prados Frutos, Juan Carlos
Martínez Álvarez, María Concepción
author_role author
author2 González-Meli, B
Martínez Sanz, Elena
Casado Gómez, Inmaculada
Martín Álvaro, María Concepción
González Aranda, Pablo
Paradas Lara, Irene
Maldonado Bautista, Estela
Maestro De Las Casas, María Del Carmen
Prados Frutos, Juan Carlos
Martínez Álvarez, María Concepción
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidad Complutense de Madrid
dc.subject.none.fl_str_mv 61
Cleft palate
Dog
Refinement
Feeding technique
Ciencias Biomédicas
24 Ciencias de la Vida
32 Ciencias Médicas
topic 61
Cleft palate
Dog
Refinement
Feeding technique
Ciencias Biomédicas
24 Ciencias de la Vida
32 Ciencias Médicas
description In humans, cleft palate (CP) is one of the most common malformations. Although surgeons use palatoplasty to close CP defects in children, its consequences for subsequent facial growth have prompted investigations into other novel surgical alternatives. The animal models of CP used to evaluate new surgical treatments are frequently obtained by creating surgically induced clefts in adult dogs. This procedure has been ethically criticized due to its severity and questionable value as an animal model for human CP. Dogs born with a congenital CP would be much better for this purpose, provided they developed CP at a sufficient rate and could be fed. Up until now, feeding these pups carried the risk of aspiration pneumonia, while impeding normal suckling and chewing, and thus compromising orofacial growth. We developed a technique for feeding dog pups with CP from birth to the time of surgery using two old Spanish pointer dog pups bearing a complete CP. This dog strain develops CP in 15-20% of the offspring spontaneously. Custom-made feeding teats and palatal prostheses adapted to the pups' palates were made from thermoplastic plates. This feeding technique allowed lactation, eating and drinking in the pups with CP, with only sporadic rhinitis. To determine whether the use of this palatal prosthesis interferes with palatal growth, the palates of three littermate German shorthaired pointer pups without CP, either wearing or not wearing (controls) the prosthesis, were measured. The results showed that the permanent use of this prosthesis does not impede palatal growth in the pups.
publishDate 2011
dc.date.none.fl_str_mv 2011
2011-01-01
2011
2011-01-01
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://hdl.handle.net/20.500.14352/101441
url https://hdl.handle.net/20.500.14352/101441
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv SAGE Publications
publisher.none.fl_str_mv SAGE Publications
dc.source.none.fl_str_mv reponame:Docta Complutense
instname:Universidad Complutense de Madrid (UCM)
instname_str Universidad Complutense de Madrid (UCM)
reponame_str Docta Complutense
collection Docta Complutense
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15.301603

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