Verbal emotional memory laterality effect on amygdalohippocampectomy for refractory epilepsy

Objectives: To study the brain lateralization of the verbal emotional memory and the influence of the emotional valence, we investigated a sample composed of patients with medial temporal lobe refractory epilepsy (MTLE) treated with unilateral amyg -dalohippocampectomy compared to a control group.Ma...

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Detalles Bibliográficos
Autores: Carvajal Molina, Fernando, Rubio Fernández, Sandra María, Martín Plasencia, Pilar, Calahorra-Romillo, Ainara
Tipo de recurso: artículo
Fecha de publicación:2020
País:España
Institución:Universidad Autónoma de Madrid
Repositorio:Biblos-e Archivo. Repositorio Institucional de la UAM
Idioma:inglés
OAI Identifier:oai:repositorio.uam.es:10486/709832
Acceso en línea:http://hdl.handle.net/10486/709832
https://dx.doi.org/10.1002/brb3.1872
Access Level:acceso abierto
Palabra clave:amygdalohippocampectomy
emotion
epilepsy
episodic memory
memory
neurosurgery
verbal emotional memory
Psicología
Descripción
Sumario:Objectives: To study the brain lateralization of the verbal emotional memory and the influence of the emotional valence, we investigated a sample composed of patients with medial temporal lobe refractory epilepsy (MTLE) treated with unilateral amyg -dalohippocampectomy compared to a control group.Materials & Methods: A new task (Verbal Association) was designed and imple -mented to assess emotional memory performance. It was applied to 62 patients with MTLE of whom 31 have been subjected to right amygdalohippocampectomy and 31 to left amygdalohippocampectomy. These patients were compared with 31 partici-pants with no cerebral pathology, as a control group.Results: (a) The control group obtained a higher number of recalled words than the rest of the groups, while the MTLE-right group obtained better results than the MTLE-left group. (b) In the case of positive emotional valence words, the MTLE-left group performed significantly worse than the rest of the groups; whereas for nega-tive emotional words, the MTLE-left group presented the lowest average perfor -mance and the control group obtained a higher number of recalled words compared to MTLE-right group. In the case of neutral emotional words, no significant differ -ences were found among the groups. (c) The MTLE-left group showed poorer perfor -mance on positive and negative words than neutral; the control group demonstrated lower average performance on positive and neutral words compared to negative; the MTLE-right group did not show any significant differences on the recall of different emotional valences.Conclusions: Patients with MTLE show a deficit in the verbal recall which is exacer -bated for information with an affective component. This deficit is more prominent in the case of patients with left unilateral resection (MTLE-left group) since they lose the benefits of the emotional information for the recall