Classifying and communicating risks in prediabetes according to fasting glucose and/or glycated hemoglobin

Information about prognostic outcomes can be of great help for people with prediabetes and for physicians in the face of scientific controversy about the cutoff point for defining prediabetes. We aimed to estimate different prognostic outcomes in people with prediabetes. Prospective cohort of subjec...

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Autores: Regidor, Enrique, Cea-Soriano, Lucía|||0000-0002-7051-0730, Ruiz, Antonio, Goday Arnó, Albert|||0000-0001-7356-1595, Carabantes, David, Díez-Espino, Javier, Artola, Sara|||0000-0002-6713-7197, Franch-Nadal, Josep|||0000-0002-5175-1555
Tipo de recurso: artículo
Fecha de publicación:2021
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:249785
Acceso en línea:https://ddd.uab.cat/record/249785
https://dx.doi.org/urn:doi:10.1080/02813432.2021.1958497
Access Level:acceso abierto
Palabra clave:Prediabetes
Absolute risk
Odds
Progression
Cohort study
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spelling Classifying and communicating risks in prediabetes according to fasting glucose and/or glycated hemoglobinPREDAPS cohort studyRegidor, EnriqueCea-Soriano, Lucía|||0000-0002-7051-0730Ruiz, AntonioGoday Arnó, Albert|||0000-0001-7356-1595Carabantes, DavidDíez-Espino, JavierArtola, Sara|||0000-0002-6713-7197Franch-Nadal, Josep|||0000-0002-5175-1555PrediabetesAbsolute riskOddsProgressionCohort studyInformation about prognostic outcomes can be of great help for people with prediabetes and for physicians in the face of scientific controversy about the cutoff point for defining prediabetes. We aimed to estimate different prognostic outcomes in people with prediabetes. Prospective cohort of subjects with prediabetes according to American Diabetes Association guidelines. The probabilities of diabetes onset versus non-onset, the odds against diabetes onset, and the probability of reverting to normoglycemia according to different prediabetes categories were calculated. The odds against diabetes onset ranged from 29:1 in individuals with isolated FPG of 100-109 mg/dL to 1:1 in individuals with FPG 110-125 mg/dL plus HbA1c 6.0-6.4%. The probability of reversion to normoglycemia was 31.2% (95% CI 24.0-39.6) in those with isolated FPG 100-109 mg/dL and 6.2% (95% CI 1.4-10.0) in those with FPG 110-125 mg/dL plus HbA1c 6.0-6.4%. Of every 100 participants in the first group, 97 did not develop diabetes and 31 reverted to normoglycemia, while in the second group those figures were 52 and 6. Using odds of probabilities and absolute numbers might be useful for people with prediabetes and physicians to share decisions on potential interventions. 22021-01-0120212021-01-01Articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttps://ddd.uab.cat/record/249785https://dx.doi.org/urn:doi:10.1080/02813432.2021.1958497reponame:Dipòsit Digital de Documents de la UABinstname:Universitat Autònoma de BarcelonaInglésengopen accesshttp://purl.org/coar/access_right/c_abf2Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.https://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:ddd.uab.cat:2497852026-06-06T12:50:31Z
dc.title.none.fl_str_mv Classifying and communicating risks in prediabetes according to fasting glucose and/or glycated hemoglobin
PREDAPS cohort study
title Classifying and communicating risks in prediabetes according to fasting glucose and/or glycated hemoglobin
spellingShingle Classifying and communicating risks in prediabetes according to fasting glucose and/or glycated hemoglobin
Regidor, Enrique
Prediabetes
Absolute risk
Odds
Progression
Cohort study
title_short Classifying and communicating risks in prediabetes according to fasting glucose and/or glycated hemoglobin
title_full Classifying and communicating risks in prediabetes according to fasting glucose and/or glycated hemoglobin
title_fullStr Classifying and communicating risks in prediabetes according to fasting glucose and/or glycated hemoglobin
title_full_unstemmed Classifying and communicating risks in prediabetes according to fasting glucose and/or glycated hemoglobin
title_sort Classifying and communicating risks in prediabetes according to fasting glucose and/or glycated hemoglobin
dc.creator.none.fl_str_mv Regidor, Enrique
Cea-Soriano, Lucía|||0000-0002-7051-0730
Ruiz, Antonio
Goday Arnó, Albert|||0000-0001-7356-1595
Carabantes, David
Díez-Espino, Javier
Artola, Sara|||0000-0002-6713-7197
Franch-Nadal, Josep|||0000-0002-5175-1555
author Regidor, Enrique
author_facet Regidor, Enrique
Cea-Soriano, Lucía|||0000-0002-7051-0730
Ruiz, Antonio
Goday Arnó, Albert|||0000-0001-7356-1595
Carabantes, David
Díez-Espino, Javier
Artola, Sara|||0000-0002-6713-7197
Franch-Nadal, Josep|||0000-0002-5175-1555
author_role author
author2 Cea-Soriano, Lucía|||0000-0002-7051-0730
Ruiz, Antonio
Goday Arnó, Albert|||0000-0001-7356-1595
Carabantes, David
Díez-Espino, Javier
Artola, Sara|||0000-0002-6713-7197
Franch-Nadal, Josep|||0000-0002-5175-1555
author2_role author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Prediabetes
Absolute risk
Odds
Progression
Cohort study
topic Prediabetes
Absolute risk
Odds
Progression
Cohort study
description Information about prognostic outcomes can be of great help for people with prediabetes and for physicians in the face of scientific controversy about the cutoff point for defining prediabetes. We aimed to estimate different prognostic outcomes in people with prediabetes. Prospective cohort of subjects with prediabetes according to American Diabetes Association guidelines. The probabilities of diabetes onset versus non-onset, the odds against diabetes onset, and the probability of reverting to normoglycemia according to different prediabetes categories were calculated. The odds against diabetes onset ranged from 29:1 in individuals with isolated FPG of 100-109 mg/dL to 1:1 in individuals with FPG 110-125 mg/dL plus HbA1c 6.0-6.4%. The probability of reversion to normoglycemia was 31.2% (95% CI 24.0-39.6) in those with isolated FPG 100-109 mg/dL and 6.2% (95% CI 1.4-10.0) in those with FPG 110-125 mg/dL plus HbA1c 6.0-6.4%. Of every 100 participants in the first group, 97 did not develop diabetes and 31 reverted to normoglycemia, while in the second group those figures were 52 and 6. Using odds of probabilities and absolute numbers might be useful for people with prediabetes and physicians to share decisions on potential interventions.
publishDate 2021
dc.date.none.fl_str_mv 2
2021-01-01
2021
2021-01-01
dc.type.none.fl_str_mv Article
http://purl.org/coar/resource_type/c_6501
VoR
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dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.none.fl_str_mv https://ddd.uab.cat/record/249785
https://dx.doi.org/urn:doi:10.1080/02813432.2021.1958497
url https://ddd.uab.cat/record/249785
https://dx.doi.org/urn:doi:10.1080/02813432.2021.1958497
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
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dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
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eu_rights_str_mv openAccess
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dc.source.none.fl_str_mv reponame:Dipòsit Digital de Documents de la UAB
instname:Universitat Autònoma de Barcelona
instname_str Universitat Autònoma de Barcelona
reponame_str Dipòsit Digital de Documents de la UAB
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