Bronchiectasis in India: results from the European Multicentre Bronchiectasis Audit and Research Collaboration (EMBARC) and Respiratory Research Network of India Registry

Bronchiectasis; EMBARC; Respiratory Research Network

Detalles Bibliográficos
Autores: Dhar, Raja, Singh, Sheetu, Talwar, Deepak, Mohan, Murali, Tripathi, Surya K., Swarnakar, Rajesh, Polverino, Eva
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2019
País:España
Institución:Departament de Salut de la Generalitat de Catalunya (DS)
Repositorio:Scientia. Dipòsit d'Informació Digital del Departament de Salut
OAI Identifier:oai:scientiasalut.gencat.cat:11351/4678
Acceso en línea:https://hdl.handle.net/11351/4678
Access Level:acceso abierto
Palabra clave:Epidemiologia clínica
Bronquièctasi - Índia
Indicadors de salut - Índia
DISEASES::Respiratory Tract Diseases::Bronchial Diseases::Bronchiectasis
ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics::Epidemiologic Studies
HEALTH CARE::Health Care Quality, Access, and Evaluation::Quality Assurance, Health Care::Health Care Quality, Access, and Evaluation::Benchmarking
GEOGRAPHICALS::Geographic Locations::Asia::Asia, Western::India
ENFERMEDADES::enfermedades respiratorias::enfermedades bronquiales::bronquiectasia
TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::técnicas de investigación::métodos epidemiológicos::características de los estudios epidemiológicos::estudios epidemiológicos
ATENCIÓN DE SALUD::calidad, acceso y evaluación de la atención sanitaria::garantía de calidad de la atención sanitaria::calidad, acceso y evaluación de la atención sanitaria::Benchmarking
DENOMINACIONES GEOGRÁFICAS::localizaciones geográficas::Asia::Asia occidental::India
id ES_bc48a8fc8d4ea43e7c002371393c2bcb
oai_identifier_str oai:scientiasalut.gencat.cat:11351/4678
network_acronym_str ES
network_name_str España
repository_id_str
dc.title.none.fl_str_mv Bronchiectasis in India: results from the European Multicentre Bronchiectasis Audit and Research Collaboration (EMBARC) and Respiratory Research Network of India Registry
title Bronchiectasis in India: results from the European Multicentre Bronchiectasis Audit and Research Collaboration (EMBARC) and Respiratory Research Network of India Registry
spellingShingle Bronchiectasis in India: results from the European Multicentre Bronchiectasis Audit and Research Collaboration (EMBARC) and Respiratory Research Network of India Registry
Dhar, Raja
Epidemiologia clínica
Bronquièctasi - Índia
Indicadors de salut - Índia
DISEASES::Respiratory Tract Diseases::Bronchial Diseases::Bronchiectasis
ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics::Epidemiologic Studies
HEALTH CARE::Health Care Quality, Access, and Evaluation::Quality Assurance, Health Care::Health Care Quality, Access, and Evaluation::Benchmarking
GEOGRAPHICALS::Geographic Locations::Asia::Asia, Western::India
ENFERMEDADES::enfermedades respiratorias::enfermedades bronquiales::bronquiectasia
TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::técnicas de investigación::métodos epidemiológicos::características de los estudios epidemiológicos::estudios epidemiológicos
ATENCIÓN DE SALUD::calidad, acceso y evaluación de la atención sanitaria::garantía de calidad de la atención sanitaria::calidad, acceso y evaluación de la atención sanitaria::Benchmarking
DENOMINACIONES GEOGRÁFICAS::localizaciones geográficas::Asia::Asia occidental::India
title_short Bronchiectasis in India: results from the European Multicentre Bronchiectasis Audit and Research Collaboration (EMBARC) and Respiratory Research Network of India Registry
title_full Bronchiectasis in India: results from the European Multicentre Bronchiectasis Audit and Research Collaboration (EMBARC) and Respiratory Research Network of India Registry
title_fullStr Bronchiectasis in India: results from the European Multicentre Bronchiectasis Audit and Research Collaboration (EMBARC) and Respiratory Research Network of India Registry
title_full_unstemmed Bronchiectasis in India: results from the European Multicentre Bronchiectasis Audit and Research Collaboration (EMBARC) and Respiratory Research Network of India Registry
title_sort Bronchiectasis in India: results from the European Multicentre Bronchiectasis Audit and Research Collaboration (EMBARC) and Respiratory Research Network of India Registry
dc.creator.none.fl_str_mv Dhar, Raja
Singh, Sheetu
Talwar, Deepak
Mohan, Murali
Tripathi, Surya K.
Swarnakar, Rajesh
Polverino, Eva
author Dhar, Raja
author_facet Dhar, Raja
Singh, Sheetu
Talwar, Deepak
Mohan, Murali
Tripathi, Surya K.
Swarnakar, Rajesh
Polverino, Eva
author_role author
author2 Singh, Sheetu
Talwar, Deepak
Mohan, Murali
Tripathi, Surya K.
Swarnakar, Rajesh
Polverino, Eva
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv [Dhar R] Department of Chest and TB, Fortis Hospital, Kolkata, India. [Singh S] Institute of Respiratory Disease, SMS Medical College, Jaipur, India. [Talwar D] Department of Respiratory Medicine, Metro centre for Respiratory Diseases, India. [Mohan M] Mazumdar Shaw Medical Centre, Narayana Hrudayalaya, Bengaluru, India. [Tripathi SK] Department of Respiratory Medicine, King George's Medical University, Lucknow, India. [Swarnakar R] Department of Respiratory Medicine, Getwell Hospital and Research Centre, Nagpur, India. [Polverino E] Servei de Pneumologia, Hospital Universitari Vall d'Hebron, Barcelona, Spain. Thorax Institute, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain
Vall d'Hebron Barcelona Hospital Campus
dc.subject.none.fl_str_mv Epidemiologia clínica
Bronquièctasi - Índia
Indicadors de salut - Índia
DISEASES::Respiratory Tract Diseases::Bronchial Diseases::Bronchiectasis
ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics::Epidemiologic Studies
HEALTH CARE::Health Care Quality, Access, and Evaluation::Quality Assurance, Health Care::Health Care Quality, Access, and Evaluation::Benchmarking
GEOGRAPHICALS::Geographic Locations::Asia::Asia, Western::India
ENFERMEDADES::enfermedades respiratorias::enfermedades bronquiales::bronquiectasia
TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::técnicas de investigación::métodos epidemiológicos::características de los estudios epidemiológicos::estudios epidemiológicos
ATENCIÓN DE SALUD::calidad, acceso y evaluación de la atención sanitaria::garantía de calidad de la atención sanitaria::calidad, acceso y evaluación de la atención sanitaria::Benchmarking
DENOMINACIONES GEOGRÁFICAS::localizaciones geográficas::Asia::Asia occidental::India
topic Epidemiologia clínica
Bronquièctasi - Índia
Indicadors de salut - Índia
DISEASES::Respiratory Tract Diseases::Bronchial Diseases::Bronchiectasis
ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics::Epidemiologic Studies
HEALTH CARE::Health Care Quality, Access, and Evaluation::Quality Assurance, Health Care::Health Care Quality, Access, and Evaluation::Benchmarking
GEOGRAPHICALS::Geographic Locations::Asia::Asia, Western::India
ENFERMEDADES::enfermedades respiratorias::enfermedades bronquiales::bronquiectasia
TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::técnicas de investigación::métodos epidemiológicos::características de los estudios epidemiológicos::estudios epidemiológicos
ATENCIÓN DE SALUD::calidad, acceso y evaluación de la atención sanitaria::garantía de calidad de la atención sanitaria::calidad, acceso y evaluación de la atención sanitaria::Benchmarking
DENOMINACIONES GEOGRÁFICAS::localizaciones geográficas::Asia::Asia occidental::India
description Bronchiectasis; EMBARC; Respiratory Research Network
publishDate 2019
dc.date.none.fl_str_mv 2019
2020
2020
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/11351/4678
url https://hdl.handle.net/11351/4678
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv The Lancet Global Health;7(9)
https://www.sciencedirect.com/science/article/pii/S2214109X19303274?via%3Dihub#!
dc.rights.none.fl_str_mv Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv Scientia
reponame:Scientia. Dipòsit d'Informació Digital del Departament de Salut
instname:Departament de Salut de la Generalitat de Catalunya (DS)
instname_str Departament de Salut de la Generalitat de Catalunya (DS)
reponame_str Scientia. Dipòsit d'Informació Digital del Departament de Salut
collection Scientia. Dipòsit d'Informació Digital del Departament de Salut
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869418100021002240
spelling Bronchiectasis in India: results from the European Multicentre Bronchiectasis Audit and Research Collaboration (EMBARC) and Respiratory Research Network of India RegistryDhar, RajaSingh, SheetuTalwar, DeepakMohan, MuraliTripathi, Surya K.Swarnakar, RajeshPolverino, EvaEpidemiologia clínicaBronquièctasi - ÍndiaIndicadors de salut - ÍndiaDISEASES::Respiratory Tract Diseases::Bronchial Diseases::BronchiectasisANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics::Epidemiologic StudiesHEALTH CARE::Health Care Quality, Access, and Evaluation::Quality Assurance, Health Care::Health Care Quality, Access, and Evaluation::BenchmarkingGEOGRAPHICALS::Geographic Locations::Asia::Asia, Western::IndiaENFERMEDADES::enfermedades respiratorias::enfermedades bronquiales::bronquiectasiaTÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS::técnicas de investigación::métodos epidemiológicos::características de los estudios epidemiológicos::estudios epidemiológicosATENCIÓN DE SALUD::calidad, acceso y evaluación de la atención sanitaria::garantía de calidad de la atención sanitaria::calidad, acceso y evaluación de la atención sanitaria::BenchmarkingDENOMINACIONES GEOGRÁFICAS::localizaciones geográficas::Asia::Asia occidental::IndiaBronchiectasis; EMBARC; Respiratory Research NetworkBronquiectàsies; EMBARC; Registre d’Investigació RespiratòriaBronquiectasias; EMBARC; Registro de Investigación RespiratoriaBACKGROUND: Bronchiectasis is a common but neglected chronic lung disease. Most epidemiological data are limited to cohorts from Europe and the USA, with few data from low-income and middle-income countries. We therefore aimed to describe the characteristics, severity of disease, microbiology, and treatment of patients with bronchiectasis in India. METHODS: The Indian bronchiectasis registry is a multicentre, prospective, observational cohort study. Adult patients (≥18 years) with CT-confirmed bronchiectasis were enrolled from 31 centres across India. Patients with bronchiectasis due to cystic fibrosis or traction bronchiectasis associated with another respiratory disorder were excluded. Data were collected at baseline (recruitment) with follow-up visits taking place once per year. Comprehensive clinical data were collected through the European Multicentre Bronchiectasis Audit and Research Collaboration registry platform. Underlying aetiology of bronchiectasis, as well as treatment and risk factors for bronchiectasis were analysed in the Indian bronchiectasis registry. Comparisons of demographics were made with published European and US registries, and quality of care was benchmarked against the 2017 European Respiratory Society guidelines. FINDINGS: From June 1, 2015, to Sept 1, 2017, 2195 patients were enrolled. Marked differences were observed between India, Europe, and the USA. Patients in India were younger (median age 56 years [IQR 41-66] vs the European and US registries; p<0·0001]) and more likely to be men (1249 [56·9%] of 2195). Previous tuberculosis (780 [35·5%] of 2195) was the most frequent underlying cause of bronchiectasis and Pseudomonas aeruginosa was the most common organism in sputum culture (301 [13·7%]) in India. Risk factors for exacerbations included being of the male sex (adjusted incidence rate ratio 1·17, 95% CI 1·03-1·32; p=0·015), P aeruginosa infection (1·29, 1·10-1·50; p=0·001), a history of pulmonary tuberculosis (1·20, 1·07-1·34; p=0·002), modified Medical Research Council Dyspnoea score (1·32, 1·25-1·39; p<0·0001), daily sputum production (1·16, 1·03-1·30; p=0·013), and radiological severity of disease (1·03, 1·01-1·04; p<0·0001). Low adherence to guideline-recommended care was observed; only 388 patients were tested for allergic bronchopulmonary aspergillosis and 82 patients had been tested for immunoglobulins. INTERPRETATION: Patients with bronchiectasis in India have more severe disease and have distinct characteristics from those reported in other countries. This study provides a benchmark to improve quality of care for patients with bronchiectasis in India.EU/European Federation of Pharmaceutical Industries and Associations Innovative Medicines Initiative inhaled Antibiotics in Bronchiectasis and Cystic Fibrosis Consortium, European Respiratory Society, and the British Lung Foundation.Elsevier[Dhar R] Department of Chest and TB, Fortis Hospital, Kolkata, India. [Singh S] Institute of Respiratory Disease, SMS Medical College, Jaipur, India. [Talwar D] Department of Respiratory Medicine, Metro centre for Respiratory Diseases, India. [Mohan M] Mazumdar Shaw Medical Centre, Narayana Hrudayalaya, Bengaluru, India. [Tripathi SK] Department of Respiratory Medicine, King George's Medical University, Lucknow, India. [Swarnakar R] Department of Respiratory Medicine, Getwell Hospital and Research Centre, Nagpur, India. [Polverino E] Servei de Pneumologia, Hospital Universitari Vall d'Hebron, Barcelona, Spain. Thorax Institute, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, SpainVall d'Hebron Barcelona Hospital Campus202020202019info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttps://hdl.handle.net/11351/4678Scientiareponame:Scientia. Dipòsit d'Informació Digital del Departament de Salutinstname:Departament de Salut de la Generalitat de Catalunya (DS)InglésThe Lancet Global Health;7(9)https://www.sciencedirect.com/science/article/pii/S2214109X19303274?via%3Dihub#!Attribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:scientiasalut.gencat.cat:11351/46782026-06-12T09:38:37Z
score 15,81155

Similares en LA Referencia