Differences in Sex and the Incidence and In-Hospital Mortality among People Admitted for Infective Endocarditis in Spain, 2016–2020

Background: A description of the trends and outcomes during hospitalization for infective endocarditis (IE) according to sex. (2) Methods: Using Spanish national hospital discharge data (2016–2020), we built Poisson regression models to compare the age-adjusted time trends for the incidence rate. We...

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Detalles Bibliográficos
Autores: Miguel Yanes, José María De, Jiménez García, Rodrigo, Miguel Díez, Javier De, Hernández Barrera, Valentín, Carabantes Alarcón, David, Zamorano León, José Javier, Noriega, Concepción, López De Andrés, Ana Isabel
Tipo de recurso: artículo
Fecha de publicación:2022
País:España
Institución:Universidad Complutense de Madrid (UCM)
Repositorio:Docta Complutense
Idioma:inglés
OAI Identifier:oai:docta.ucm.es:20.500.14352/72301
Acceso en línea:https://hdl.handle.net/20.500.14352/72301
Access Level:acceso abierto
Palabra clave:616.126-002
Infective endocarditis
Sex
Heart valve surgery
Comorbidities
In-hospital mortality
Medicina
Cardiología
Enfermedades infecciosas
32 Ciencias Médicas
3205.01 Cardiología
3205.05 Enfermedades Infecciosas
Descripción
Sumario:Background: A description of the trends and outcomes during hospitalization for infective endocarditis (IE) according to sex. (2) Methods: Using Spanish national hospital discharge data (2016–2020), we built Poisson regression models to compare the age-adjusted time trends for the incidence rate. We used propensity score matching (PSM) to compare the clinical characteristics and the in-hospital mortality (IHM) between men and women hospitalized with IE. (3) Results: We identified 10,459 hospitalizations for IE (33.26% women). The incidence of IE remained stable during this five-year period. The age-adjusted incidence of IE was two-fold higher among men vs. women (IRR = 2.08; 95%CI 2.0–2.17). Before PSM, women with IE were significantly older than men (70.25 vs. 66.24 years; p < 0.001) and had lower comorbidity according to the Charlson comorbidity index (mean 1.38 vs. 1.43; p = 0.019). After PSM, the IHM among women admitted for IE remained >3 points higher than that among men (19.52% vs. 15.98%; p < 0.001). (4) Conclusions: The incidence of IE was two-fold higher among men than among women. IHM was significantly higher among women after accounting for the potential confounders.

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