Neurologists’ Openness to Evidence-Based Innovation in Multiple Sclerosis Care: Individual and Structural Determinants

Purpose: Integration of evidence-based innovations, such as serum neurofilament light chain (sNfL) measurement into routine practice represents a pivotal opportunity to advance personalized care in multiple sclerosis (MS) management. This study assessed neurologists' openness to adopting health...

Descripción completa

Detalles Bibliográficos
Autores: Monreal, Enric, Gómez Ballesteros, Rocío, Meca Lallana, Virginia, Caminero, Ana, Meca Lallana, José E., Martínez Yélamos, Sergio, Landete, Lamberto, García Domínguez, José M., Agüera, Eduardo, García Arcelay, Elena, Medrano, Nicolas, Villar, Luisa M., Maurino, Jorge
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2025
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/222834
Acceso en línea:https://hdl.handle.net/2445/222834
Access Level:acceso abierto
Palabra clave:Esclerosi múltiple
Medicina basada en l'evidència
Multiple sclerosis
Evidence-based medicine
id ES_bbdac5a2b20e5f05ef7a6e01780dfd79
oai_identifier_str oai:recercat.cat:2445/222834
network_acronym_str ES
network_name_str España
repository_id_str
spelling Neurologists’ Openness to Evidence-Based Innovation in Multiple Sclerosis Care: Individual and Structural DeterminantsMonreal, EnricGómez Ballesteros, RocíoMeca Lallana, VirginiaCaminero, AnaMeca Lallana, José E.Martínez Yélamos, SergioLandete, LambertoGarcía Domínguez, José M.Agüera, EduardoGarcía Arcelay, ElenaMedrano, NicolasVillar, Luisa M.Maurino, JorgeEsclerosi múltipleMedicina basada en l'evidènciaMultiple sclerosisEvidence-based medicinePurpose: Integration of evidence-based innovations, such as serum neurofilament light chain (sNfL) measurement into routine practice represents a pivotal opportunity to advance personalized care in multiple sclerosis (MS) management. This study assessed neurologists' openness to adopting healthcare innovations (sNfL testing), focusing on individual characteristics and structural factors like workplace environment and resources. Methods: An observational, cross-sectional study was conducted in partnership with the Spanish Society of Neurology. Neurologists caring for patients with MS completed an e-survey assessing openness to innovation using the Openness subscale of the EvidenceBased Practice Attitude Scale (EBPAS), alongside measures of empathy, healthcare-related regret, risk preferences, burnout, and workplace communication. Logistic and linear regression models were conducted to identify predictors of openness to innovation. Results: One hundred and sixteen neurologists were studied. Mean age (SD) was 41.9 (10.1) years, 53.4% were male. Mean experience as neurologists was 16.0 (9.2) years and 96.6% worked in an academic hospital. Median (IQR) EBPAS-Openness score was 3.0 (2.5-3.5), with 54.3% (n=63) of participants demonstrating openness to innovation. Participants fully dedicated to MS care, managing higher patient volumes, engaged in research publications, with access to serum neurofilament light chain testing, and a greater propensity for risk-taking, were more open to adopting innovations than their counterparts. Multivariate logistic regression analysis showed that access to sNfL testing and higher empathy levels were significant predictors of openness (OR=3.52, CI 95%: 1.3-10.3; p=0.016 and OR=1.09, CI 95%: 1.0-1.2; p=0.005, respectively). Complementary linear regression reinforced the significant positive association between higher EBPAS-Openness scores and empathy (estimate=0.024, p=0.001). Conclusion: Neurologists exhibited a varied openness to innovation. Implementing initial innovative strategies in clinical practice should prioritize neurologists with specific profiles to support the integration of emerging tools and personalized healthcare approaches in MS care.Informa UK Limited2025202520252025info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion9 p.application/pdfhttps://hdl.handle.net/2445/222834Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))reponame:Recercat. Dipósit de la Recerca de Catalunyainstname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)InglésReproducció del document publicat a: https://doi.org/10.2147/NDT.S524459Neuropsychiatric Disease and Treatment, 2025, vol. 21, p. 1523-1531https://doi.org/10.2147/NDT.S524459cc-by-nc (c) Monreal, Enric et al., 2025http://creativecommons.org/licenses/by-nc/3.0/es/info:eu-repo/semantics/openAccessoai:recercat.cat:2445/2228342026-05-29T05:05:01Z
dc.title.none.fl_str_mv Neurologists’ Openness to Evidence-Based Innovation in Multiple Sclerosis Care: Individual and Structural Determinants
title Neurologists’ Openness to Evidence-Based Innovation in Multiple Sclerosis Care: Individual and Structural Determinants
spellingShingle Neurologists’ Openness to Evidence-Based Innovation in Multiple Sclerosis Care: Individual and Structural Determinants
Monreal, Enric
Esclerosi múltiple
Medicina basada en l'evidència
Multiple sclerosis
Evidence-based medicine
title_short Neurologists’ Openness to Evidence-Based Innovation in Multiple Sclerosis Care: Individual and Structural Determinants
title_full Neurologists’ Openness to Evidence-Based Innovation in Multiple Sclerosis Care: Individual and Structural Determinants
title_fullStr Neurologists’ Openness to Evidence-Based Innovation in Multiple Sclerosis Care: Individual and Structural Determinants
title_full_unstemmed Neurologists’ Openness to Evidence-Based Innovation in Multiple Sclerosis Care: Individual and Structural Determinants
title_sort Neurologists’ Openness to Evidence-Based Innovation in Multiple Sclerosis Care: Individual and Structural Determinants
dc.creator.none.fl_str_mv Monreal, Enric
Gómez Ballesteros, Rocío
Meca Lallana, Virginia
Caminero, Ana
Meca Lallana, José E.
Martínez Yélamos, Sergio
Landete, Lamberto
García Domínguez, José M.
Agüera, Eduardo
García Arcelay, Elena
Medrano, Nicolas
Villar, Luisa M.
Maurino, Jorge
author Monreal, Enric
author_facet Monreal, Enric
Gómez Ballesteros, Rocío
Meca Lallana, Virginia
Caminero, Ana
Meca Lallana, José E.
Martínez Yélamos, Sergio
Landete, Lamberto
García Domínguez, José M.
Agüera, Eduardo
García Arcelay, Elena
Medrano, Nicolas
Villar, Luisa M.
Maurino, Jorge
author_role author
author2 Gómez Ballesteros, Rocío
Meca Lallana, Virginia
Caminero, Ana
Meca Lallana, José E.
Martínez Yélamos, Sergio
Landete, Lamberto
García Domínguez, José M.
Agüera, Eduardo
García Arcelay, Elena
Medrano, Nicolas
Villar, Luisa M.
Maurino, Jorge
author2_role author
author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Esclerosi múltiple
Medicina basada en l'evidència
Multiple sclerosis
Evidence-based medicine
topic Esclerosi múltiple
Medicina basada en l'evidència
Multiple sclerosis
Evidence-based medicine
description Purpose: Integration of evidence-based innovations, such as serum neurofilament light chain (sNfL) measurement into routine practice represents a pivotal opportunity to advance personalized care in multiple sclerosis (MS) management. This study assessed neurologists' openness to adopting healthcare innovations (sNfL testing), focusing on individual characteristics and structural factors like workplace environment and resources. Methods: An observational, cross-sectional study was conducted in partnership with the Spanish Society of Neurology. Neurologists caring for patients with MS completed an e-survey assessing openness to innovation using the Openness subscale of the EvidenceBased Practice Attitude Scale (EBPAS), alongside measures of empathy, healthcare-related regret, risk preferences, burnout, and workplace communication. Logistic and linear regression models were conducted to identify predictors of openness to innovation. Results: One hundred and sixteen neurologists were studied. Mean age (SD) was 41.9 (10.1) years, 53.4% were male. Mean experience as neurologists was 16.0 (9.2) years and 96.6% worked in an academic hospital. Median (IQR) EBPAS-Openness score was 3.0 (2.5-3.5), with 54.3% (n=63) of participants demonstrating openness to innovation. Participants fully dedicated to MS care, managing higher patient volumes, engaged in research publications, with access to serum neurofilament light chain testing, and a greater propensity for risk-taking, were more open to adopting innovations than their counterparts. Multivariate logistic regression analysis showed that access to sNfL testing and higher empathy levels were significant predictors of openness (OR=3.52, CI 95%: 1.3-10.3; p=0.016 and OR=1.09, CI 95%: 1.0-1.2; p=0.005, respectively). Complementary linear regression reinforced the significant positive association between higher EBPAS-Openness scores and empathy (estimate=0.024, p=0.001). Conclusion: Neurologists exhibited a varied openness to innovation. Implementing initial innovative strategies in clinical practice should prioritize neurologists with specific profiles to support the integration of emerging tools and personalized healthcare approaches in MS care.
publishDate 2025
dc.date.none.fl_str_mv 2025
2025
2025
2025
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/222834
url https://hdl.handle.net/2445/222834
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Reproducció del document publicat a: https://doi.org/10.2147/NDT.S524459
Neuropsychiatric Disease and Treatment, 2025, vol. 21, p. 1523-1531
https://doi.org/10.2147/NDT.S524459
dc.rights.none.fl_str_mv cc-by-nc (c) Monreal, Enric et al., 2025
http://creativecommons.org/licenses/by-nc/3.0/es/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv cc-by-nc (c) Monreal, Enric et al., 2025
http://creativecommons.org/licenses/by-nc/3.0/es/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 9 p.
application/pdf
dc.publisher.none.fl_str_mv Informa UK Limited
publisher.none.fl_str_mv Informa UK Limited
dc.source.none.fl_str_mv Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))
reponame:Recercat. Dipósit de la Recerca de Catalunya
instname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
instname_str Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
reponame_str Recercat. Dipósit de la Recerca de Catalunya
collection Recercat. Dipósit de la Recerca de Catalunya
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869418062105542656
score 15.811543

Similares en LA Referencia