Incidence of persistent postoperative pain after hepatectomies with 2 regimes of perioperative analgesia containing ketamine

Studies designed to assess persistent postoperative pain (PPP) incidence after hepatectomies are lacking. Our aim was to assess PPP incidence 6 months after hepatectomies with intravenous (IV) or epidural (EPI) analgesia containing ketamine. Prospective observational comparative study between 2 coho...

Descripción completa

Detalles Bibliográficos
Autores: Masgoret, Paula, Gomar Sancho, Carmen, Tena Blanco, Beatriz, Taurá, Pilar, Ríos, José, Coca Martínez, Miquel
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2017
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/120751
Acceso en línea:https://hdl.handle.net/2445/120751
Access Level:acceso abierto
Palabra clave:Dolor postoperatori
Hepatectomia
Postoperative pain
Hepatectomy
id ES_bbb53301dedc1e33cf31f881aa774a21
oai_identifier_str oai:recercat.cat:2445/120751
network_acronym_str ES
network_name_str España
repository_id_str
spelling Incidence of persistent postoperative pain after hepatectomies with 2 regimes of perioperative analgesia containing ketamineMasgoret, PaulaGomar Sancho, CarmenTena Blanco, BeatrizTaurá, PilarRíos, JoséCoca Martínez, MiquelDolor postoperatoriHepatectomiaPostoperative painHepatectomyStudies designed to assess persistent postoperative pain (PPP) incidence after hepatectomies are lacking. Our aim was to assess PPP incidence 6 months after hepatectomies with intravenous (IV) or epidural (EPI) analgesia containing ketamine. Prospective observational comparative study between 2 cohorts of patients submitted to hepatectomy. Patients received 1 of 2 analgesic regimes containing ketamine: EPI group or IV group. Visual analog scale (VAS), Neuropathic Pain Symptom Inventory (NPSI), Pain Catastrophizing Scale (PCS), and quantitative sensorial testing (QST: to determine area of hyperalgesia/allodynia) were assessed preoperatively and postoperatively at 2 h, 24 h, 7 days, 1 month, and 6 months. VAS ≥ 1 at 1 and 6 months was considered indicative of PPP and VAS > 3 was considered as not controlled pain. Side effects and complications were registered. Forty-four patients were included: 23 in EPI group and 21 in IV group. Patients in IV group were older and had more comorbidities. No patient presented VAS > 3 at 1 or 6 months. VAS ≥ 1 at 1 and 6 months was 36.4% and 22.7%, respectively. No differences in VAS, NPSI, or PCS were found between groups. Allodynia/hyperalgesia area did not differ between groups and was infrequent and slight. Pain pressure threshold in the wound vertical component was significantly higher in EPI group after 7 days. IV group showed more cognitive side effects. Incidence of PPP at 6 months after open hepatectomies with EPI or IV analgesia containing ketamine was lower than previously reported for other abdominal surgeries. Ketamine influence on low PPP incidence and hyperalgesia cannot be discarded.Lippincott, Williams & Wilkins. Wolters Kluwer Health2018201820172018info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://hdl.handle.net/2445/120751Articles publicats en revistes (Cirurgia i Especialitats Medicoquirúrgiques)reponame:Recercat. Dipósit de la Recerca de Catalunyainstname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)InglésReproducció del document publicat a: https://doi.org/10.1097/MD.0000000000006624Medicine, 2017, vol. 96, num. 15, p. e6624https://doi.org/10.1097/MD.0000000000006624cc-by (c) Masgoret, Paula et al., 2017http://creativecommons.org/licenses/by/3.0/esinfo:eu-repo/semantics/openAccessoai:recercat.cat:2445/1207512026-05-29T05:05:01Z
dc.title.none.fl_str_mv Incidence of persistent postoperative pain after hepatectomies with 2 regimes of perioperative analgesia containing ketamine
title Incidence of persistent postoperative pain after hepatectomies with 2 regimes of perioperative analgesia containing ketamine
spellingShingle Incidence of persistent postoperative pain after hepatectomies with 2 regimes of perioperative analgesia containing ketamine
Masgoret, Paula
Dolor postoperatori
Hepatectomia
Postoperative pain
Hepatectomy
title_short Incidence of persistent postoperative pain after hepatectomies with 2 regimes of perioperative analgesia containing ketamine
title_full Incidence of persistent postoperative pain after hepatectomies with 2 regimes of perioperative analgesia containing ketamine
title_fullStr Incidence of persistent postoperative pain after hepatectomies with 2 regimes of perioperative analgesia containing ketamine
title_full_unstemmed Incidence of persistent postoperative pain after hepatectomies with 2 regimes of perioperative analgesia containing ketamine
title_sort Incidence of persistent postoperative pain after hepatectomies with 2 regimes of perioperative analgesia containing ketamine
dc.creator.none.fl_str_mv Masgoret, Paula
Gomar Sancho, Carmen
Tena Blanco, Beatriz
Taurá, Pilar
Ríos, José
Coca Martínez, Miquel
author Masgoret, Paula
author_facet Masgoret, Paula
Gomar Sancho, Carmen
Tena Blanco, Beatriz
Taurá, Pilar
Ríos, José
Coca Martínez, Miquel
author_role author
author2 Gomar Sancho, Carmen
Tena Blanco, Beatriz
Taurá, Pilar
Ríos, José
Coca Martínez, Miquel
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv Dolor postoperatori
Hepatectomia
Postoperative pain
Hepatectomy
topic Dolor postoperatori
Hepatectomia
Postoperative pain
Hepatectomy
description Studies designed to assess persistent postoperative pain (PPP) incidence after hepatectomies are lacking. Our aim was to assess PPP incidence 6 months after hepatectomies with intravenous (IV) or epidural (EPI) analgesia containing ketamine. Prospective observational comparative study between 2 cohorts of patients submitted to hepatectomy. Patients received 1 of 2 analgesic regimes containing ketamine: EPI group or IV group. Visual analog scale (VAS), Neuropathic Pain Symptom Inventory (NPSI), Pain Catastrophizing Scale (PCS), and quantitative sensorial testing (QST: to determine area of hyperalgesia/allodynia) were assessed preoperatively and postoperatively at 2 h, 24 h, 7 days, 1 month, and 6 months. VAS ≥ 1 at 1 and 6 months was considered indicative of PPP and VAS > 3 was considered as not controlled pain. Side effects and complications were registered. Forty-four patients were included: 23 in EPI group and 21 in IV group. Patients in IV group were older and had more comorbidities. No patient presented VAS > 3 at 1 or 6 months. VAS ≥ 1 at 1 and 6 months was 36.4% and 22.7%, respectively. No differences in VAS, NPSI, or PCS were found between groups. Allodynia/hyperalgesia area did not differ between groups and was infrequent and slight. Pain pressure threshold in the wound vertical component was significantly higher in EPI group after 7 days. IV group showed more cognitive side effects. Incidence of PPP at 6 months after open hepatectomies with EPI or IV analgesia containing ketamine was lower than previously reported for other abdominal surgeries. Ketamine influence on low PPP incidence and hyperalgesia cannot be discarded.
publishDate 2017
dc.date.none.fl_str_mv 2017
2018
2018
2018
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/120751
url https://hdl.handle.net/2445/120751
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Reproducció del document publicat a: https://doi.org/10.1097/MD.0000000000006624
Medicine, 2017, vol. 96, num. 15, p. e6624
https://doi.org/10.1097/MD.0000000000006624
dc.rights.none.fl_str_mv cc-by (c) Masgoret, Paula et al., 2017
http://creativecommons.org/licenses/by/3.0/es
info:eu-repo/semantics/openAccess
rights_invalid_str_mv cc-by (c) Masgoret, Paula et al., 2017
http://creativecommons.org/licenses/by/3.0/es
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Lippincott, Williams & Wilkins. Wolters Kluwer Health
publisher.none.fl_str_mv Lippincott, Williams & Wilkins. Wolters Kluwer Health
dc.source.none.fl_str_mv Articles publicats en revistes (Cirurgia i Especialitats Medicoquirúrgiques)
reponame:Recercat. Dipósit de la Recerca de Catalunya
instname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
instname_str Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
reponame_str Recercat. Dipósit de la Recerca de Catalunya
collection Recercat. Dipósit de la Recerca de Catalunya
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869418049445036032
score 15,81155

Similares en LA Referencia