Impact of prefrontal theta burst stimulation on clinical neuropsychological tasks

Theta burst stimulation (TBS) protocols hold high promise in neuropsychological rehabilitation. Nevertheless, their ability to either decrease (continuous, cTBS) or increase (intermittent, iTBS) cortical excitability in areas other than the primary motor cortex, and their consistency modulating huma...

Descripción completa

Detalles Bibliográficos
Autores: Viejo-Sobera, Raquel, Redolar-Ripoll, Diego Emilia, Boixadós, Mercè, Palaus Gallego, Marc, Valero-Cabré, Antoni, Muñoz Marrón, Elena
Tipo de recurso: artículo
Fecha de publicación:2017
País:España
Institución:Universitat Oberta de Catalunya (UOC)
Repositorio:O2, repositorio institucional de la UOC
OAI Identifier:oai:openaccess.uoc.edu:10609/70626
Acceso en línea:http://hdl.handle.net/10609/70626
Access Level:acceso abierto
Palabra clave:dorsolateral prefrontal cortex
executive functions
n-back
non-invasive brain stimulation
corteza prefrontal dorsolateral
función ejecutiva
estimulación cerebral no invasiva
escorça prefrontal dorsolateral
funció executiva
estimulació cerebral no invasiva
Clinical neuropsychology
Neuropsicologia clínica
Neuropsicología clínica
Descripción
Sumario:Theta burst stimulation (TBS) protocols hold high promise in neuropsychological rehabilitation. Nevertheless, their ability to either decrease (continuous, cTBS) or increase (intermittent, iTBS) cortical excitability in areas other than the primary motor cortex, and their consistency modulating human behaviors with clinically relevant tasks remain to be fully established. The behavioral effects of TBS over the dorsolateral prefrontal cortex (dlPFC) are particularly interesting given its involvement in working memory (WM) and executive functions (EF), often impaired following frontal brain damage. We aimed to explore the ability of cTBS and iTBS to modulate WM and EF in healthy individuals, assessed with clinical neuropsychological tests (Digits Backward, 3-back task, Stroop Test, and Tower of Hanoi).