Characteristics and prognosis of patients with acute heart failure without troponin determination: The EAHFE-TROPICA3 study

Background. - The absence of cardiac troponin (cTn) determination in an episode of acute heart failure (AHF) is frequent. The characteristics of these patients are not well known; nor is it known whether they have a better prognosis than patients in whom cTn is determined. Aim. - The objective of th...

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Autores: Roset, A, Jacob, J, Herrero-Puente, P, Alquezar, A, Martin-Sanchez, FJ, Llorens, P, Llauger, L, Gil, V, Miro, O
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2019
País:España
Institución:Institut d’Investigació Biomèdica Sant Pau (IIB Sant Pau)
Repositorio:r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
OAI Identifier:oai:iibsantpau.fundanetsuite.com:p2637
Acceso en línea:https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=2637
Access Level:acceso abierto
Palabra clave:Acute heart failure
Troponin
Prognosis
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spelling Characteristics and prognosis of patients with acute heart failure without troponin determination: The EAHFE-TROPICA3 studyRoset, AJacob, JHerrero-Puente, PAlquezar, AMartin-Sanchez, FJLlorens, PLlauger, LGil, VMiro, OAcute heart failureTroponinPrognosisBackground. - The absence of cardiac troponin (cTn) determination in an episode of acute heart failure (AHF) is frequent. The characteristics of these patients are not well known; nor is it known whether they have a better prognosis than patients in whom cTn is determined. Aim. - The objective of the EAHFE-TROPICA3 study was to analyse the characteristics of patients consulting for AHF in whom cTn was not determined (nocTn), and to evaluate the relationship of cTn determination (wcTn) with patient outcomes. Methods. - This was an analysis of the multipurpose prospective EAHFE registry of patients with AHF consulting at the emergency departments of 34 Spanish hospitals. Results. - Data from 8850 patients with AHF were analysed; cTn was not determined in 4216 of these patients (47.6%), who had a lower prevalence of ischaemic heart disease, more frequent use of loop diuretics at baseline, a greater rate of oedema in the acute episode, more frequent history of heart failure, and less use of angiotensin-converting enzyme inhibitors or aldosterone receptor antagonists and beta-blockers at baseline. Compared with the wcTn group, the nocTn group had the same in-hospital mortality (adjusted odds ratio [OR] 1.21, 95% confidence interval [CI] 0.98-1.50), mortality at 30 days (adjusted OR 1.07, 95% CI 0.90-1.28) and reconsultation at 30 days (adjusted OR 0.90, 95% CI 0.80-1.02). Conclusions. - Patients presenting with AHF with and without cTn determination have different characteristics. These differences are not related to a better prognosis. (C) 2019 Elsevier Masson SAS. All rights reserved.ELSEVIER MASSON, CORPORATION OFFICE2019info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttps://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=2637Archives of Cardiovascular DiseasesISSN: 18752136ISSNe: 18752128reponame:r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pauinstname:Institut d’Investigació Biomèdica Sant Pau (IIB Sant Pau)Inglésinfo:eu-repo/semantics/openAccessoai:iibsantpau.fundanetsuite.com:p26372026-06-14T12:41:47Z
dc.title.none.fl_str_mv Characteristics and prognosis of patients with acute heart failure without troponin determination: The EAHFE-TROPICA3 study
title Characteristics and prognosis of patients with acute heart failure without troponin determination: The EAHFE-TROPICA3 study
spellingShingle Characteristics and prognosis of patients with acute heart failure without troponin determination: The EAHFE-TROPICA3 study
Roset, A
Acute heart failure
Troponin
Prognosis
title_short Characteristics and prognosis of patients with acute heart failure without troponin determination: The EAHFE-TROPICA3 study
title_full Characteristics and prognosis of patients with acute heart failure without troponin determination: The EAHFE-TROPICA3 study
title_fullStr Characteristics and prognosis of patients with acute heart failure without troponin determination: The EAHFE-TROPICA3 study
title_full_unstemmed Characteristics and prognosis of patients with acute heart failure without troponin determination: The EAHFE-TROPICA3 study
title_sort Characteristics and prognosis of patients with acute heart failure without troponin determination: The EAHFE-TROPICA3 study
dc.creator.none.fl_str_mv Roset, A
Jacob, J
Herrero-Puente, P
Alquezar, A
Martin-Sanchez, FJ
Llorens, P
Llauger, L
Gil, V
Miro, O
author Roset, A
author_facet Roset, A
Jacob, J
Herrero-Puente, P
Alquezar, A
Martin-Sanchez, FJ
Llorens, P
Llauger, L
Gil, V
Miro, O
author_role author
author2 Jacob, J
Herrero-Puente, P
Alquezar, A
Martin-Sanchez, FJ
Llorens, P
Llauger, L
Gil, V
Miro, O
author2_role author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Acute heart failure
Troponin
Prognosis
topic Acute heart failure
Troponin
Prognosis
description Background. - The absence of cardiac troponin (cTn) determination in an episode of acute heart failure (AHF) is frequent. The characteristics of these patients are not well known; nor is it known whether they have a better prognosis than patients in whom cTn is determined. Aim. - The objective of the EAHFE-TROPICA3 study was to analyse the characteristics of patients consulting for AHF in whom cTn was not determined (nocTn), and to evaluate the relationship of cTn determination (wcTn) with patient outcomes. Methods. - This was an analysis of the multipurpose prospective EAHFE registry of patients with AHF consulting at the emergency departments of 34 Spanish hospitals. Results. - Data from 8850 patients with AHF were analysed; cTn was not determined in 4216 of these patients (47.6%), who had a lower prevalence of ischaemic heart disease, more frequent use of loop diuretics at baseline, a greater rate of oedema in the acute episode, more frequent history of heart failure, and less use of angiotensin-converting enzyme inhibitors or aldosterone receptor antagonists and beta-blockers at baseline. Compared with the wcTn group, the nocTn group had the same in-hospital mortality (adjusted odds ratio [OR] 1.21, 95% confidence interval [CI] 0.98-1.50), mortality at 30 days (adjusted OR 1.07, 95% CI 0.90-1.28) and reconsultation at 30 days (adjusted OR 0.90, 95% CI 0.80-1.02). Conclusions. - Patients presenting with AHF with and without cTn determination have different characteristics. These differences are not related to a better prognosis. (C) 2019 Elsevier Masson SAS. All rights reserved.
publishDate 2019
dc.date.none.fl_str_mv 2019
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=2637
url https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=2637
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv ELSEVIER MASSON, CORPORATION OFFICE
publisher.none.fl_str_mv ELSEVIER MASSON, CORPORATION OFFICE
dc.source.none.fl_str_mv Archives of Cardiovascular Diseases
ISSN: 18752136
ISSNe: 18752128
reponame:r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname:Institut d’Investigació Biomèdica Sant Pau (IIB Sant Pau)
instname_str Institut d’Investigació Biomèdica Sant Pau (IIB Sant Pau)
reponame_str r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
collection r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
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