Language-specific regions in the supplementary motor area: evidence from verb generation during electrical stimulation mapping

Language representation has been attributed to the perisylvian areas of the left hemisphere, with a more widely distributed network in multilingual populations. However, multilingual evidence has long obviated the involvement of regions outside classical perisylvian areas, such as the supplementary...

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Detalles Bibliográficos
Autores: Hernández Pardo, Mireia, Gasa-Roqué, Anna, Gómez Andrés, Alba, Lau, Ruth, Rico, Imma, Juncadella i Puig, Montserrat, Camins, Àngels, Rodríguez Fornells, Antoni, Gabarrós, Andreu
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2025
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/223687
Acceso en línea:https://hdl.handle.net/2445/223687
Access Level:acceso abierto
Palabra clave:Neurolingüística
Mapatge del cervell
Estimulació del cervell
Neurolinguistics
Brain mapping
Brain stimulation
Descripción
Sumario:Language representation has been attributed to the perisylvian areas of the left hemisphere, with a more widely distributed network in multilingual populations. However, multilingual evidence has long obviated the involvement of regions outside classical perisylvian areas, such as the supplementary motor area (SMA). We aimed to provide novel evidence on the SMA's role in language localization using electrical stimulation mapping (ESM) during awake brain surgery. We conducted a case-series study of 4 bilingual or multilingual patients with an expansive brain lesion near the SMA who underwent an ESM. Our results evidenced that the stimulation of the left-SMA induced language difficulties during a verb generation task, with a higher proportion of languagespecific sites in the pre-SMA region. Moreover, we reported specific language sites for multiple acquired languages. Overall, our study highlighted the SMA as a language-eloquent area, likely linked to lexical decisions, while also being sensitive to different-but not necessarily all-languages of a patient.