Role of microbial communities in the pathogenesis of periodontal diseases and caries

: The microbiological characteristics of both caries and periodontal disease show significant change from those in health. In both instances, there is evidence of co-association of different organisms into consortia. Aim: We review and summarize a number of issues pertinent to the community organiza...

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Autores: Mira A, Simon-Soro A, Curtis MA
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2017
País:España
Institución:Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
Repositorio:r-FISABIO. Repositorio Institucional de Producción Científica
OAI Identifier:oai:fisabio.fundanetsuite.com:p1855
Acceso en línea:https://fisabio.portalinvestigacion.com/publicaciones/1855
Access Level:acceso abierto
Palabra clave:caries
microbial communities
oral microbiome
periodontal disease
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spelling Role of microbial communities in the pathogenesis of periodontal diseases and cariesMira ASimon-Soro ACurtis MAcariesmicrobial communitiesoral microbiomeperiodontal disease: The microbiological characteristics of both caries and periodontal disease show significant change from those in health. In both instances, there is evidence of co-association of different organisms into consortia. Aim: We review and summarize a number of issues pertinent to the community organization and functional activity of the bacterial populations resident on supra-and subgingival tooth surface and the influence of these populations on disease. Methods: A literature review was undertaken with a particular emphasis on recent publications involving high-throughput, deep sequencing approaches to the analysis of microbial populations and their functional activity. Results: There is increasing evidence to suggest that both caries and periodontal disease represent dysbiotic states of the oral microbiome. The mode of acquisition of the oral microbial communities may be less passive than previously recognized but once established remains relatively stable within an individual although there are very significant site variations. A repertoire of stable dysbiotic states may occur in both caries and periodontitis involving different microbial community structures with potentially similar functional properties. Conclusions: The processes which underlie the development and stability of microbial populations in the healthy mouth are fundamental to understanding how these populations are transformed into a dysbiotic state in disease.WILEY2017info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttps://fisabio.portalinvestigacion.com/publicaciones/1855JOURNAL OF CLINICAL PERIODONTOLOGYISSN: 03036979ISSNe: 1600051Xreponame:r-FISABIO. Repositorio Institucional de Producción Científicainstname:Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)Inglésinfo:eu-repo/semantics/openAccessoai:fisabio.fundanetsuite.com:p18552026-06-11T12:45:17Z
dc.title.none.fl_str_mv Role of microbial communities in the pathogenesis of periodontal diseases and caries
title Role of microbial communities in the pathogenesis of periodontal diseases and caries
spellingShingle Role of microbial communities in the pathogenesis of periodontal diseases and caries
Mira A
caries
microbial communities
oral microbiome
periodontal disease
title_short Role of microbial communities in the pathogenesis of periodontal diseases and caries
title_full Role of microbial communities in the pathogenesis of periodontal diseases and caries
title_fullStr Role of microbial communities in the pathogenesis of periodontal diseases and caries
title_full_unstemmed Role of microbial communities in the pathogenesis of periodontal diseases and caries
title_sort Role of microbial communities in the pathogenesis of periodontal diseases and caries
dc.creator.none.fl_str_mv Mira A
Simon-Soro A
Curtis MA
author Mira A
author_facet Mira A
Simon-Soro A
Curtis MA
author_role author
author2 Simon-Soro A
Curtis MA
author2_role author
author
dc.subject.none.fl_str_mv caries
microbial communities
oral microbiome
periodontal disease
topic caries
microbial communities
oral microbiome
periodontal disease
description : The microbiological characteristics of both caries and periodontal disease show significant change from those in health. In both instances, there is evidence of co-association of different organisms into consortia. Aim: We review and summarize a number of issues pertinent to the community organization and functional activity of the bacterial populations resident on supra-and subgingival tooth surface and the influence of these populations on disease. Methods: A literature review was undertaken with a particular emphasis on recent publications involving high-throughput, deep sequencing approaches to the analysis of microbial populations and their functional activity. Results: There is increasing evidence to suggest that both caries and periodontal disease represent dysbiotic states of the oral microbiome. The mode of acquisition of the oral microbial communities may be less passive than previously recognized but once established remains relatively stable within an individual although there are very significant site variations. A repertoire of stable dysbiotic states may occur in both caries and periodontitis involving different microbial community structures with potentially similar functional properties. Conclusions: The processes which underlie the development and stability of microbial populations in the healthy mouth are fundamental to understanding how these populations are transformed into a dysbiotic state in disease.
publishDate 2017
dc.date.none.fl_str_mv 2017
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://fisabio.portalinvestigacion.com/publicaciones/1855
url https://fisabio.portalinvestigacion.com/publicaciones/1855
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv WILEY
publisher.none.fl_str_mv WILEY
dc.source.none.fl_str_mv JOURNAL OF CLINICAL PERIODONTOLOGY
ISSN: 03036979
ISSNe: 1600051X
reponame:r-FISABIO. Repositorio Institucional de Producción Científica
instname:Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
instname_str Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
reponame_str r-FISABIO. Repositorio Institucional de Producción Científica
collection r-FISABIO. Repositorio Institucional de Producción Científica
repository.name.fl_str_mv
repository.mail.fl_str_mv
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