The trachylobane diterpenes

Tetracyclic diterpenes such as ent-kaur-16-ene (4), ent-beyer-15-ene (5) and ent-atis-16-ene (6) are an important group of natural diterpenes. The trachylobane family is related to these compounds and characterized by a pentacyclic carbon.skeleton (7) with a tricyclo 3,2,1,0 octane system for the ri...

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Bibliographic Details
Author: Fraga, Braulio M.
Format: article
Publication Date:1994
Country:España
Institution:Consejo Superior de Investigaciones Científicas (CSIC)
Repository:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/21573
Online Access:http://hdl.handle.net/10261/21573
Access Level:Open access
Keyword:Diterpenes
Trachylobane
Natural cyclopropane derivatives
Spectroscopic properties
Description
Summary:Tetracyclic diterpenes such as ent-kaur-16-ene (4), ent-beyer-15-ene (5) and ent-atis-16-ene (6) are an important group of natural diterpenes. The trachylobane family is related to these compounds and characterized by a pentacyclic carbon.skeleton (7) with a tricyclo 3,2,1,0 octane system for the rings C, D, and E. Some authors, using the nomenclature proposed by Rowe (1968), have named this series as ent-13,16- cycloatisane. In this paper we have reviewed the natural occurrence, isolation, biosynthesis, chemistry, spectroscopic properties and bioactivity of the trachylobane class of diterpenes.