Oikopleura dioica: An Emergent Chordate Model to Study the Impact of Gene Loss on the Evolution of the Mechanisms of Development.

The urochordate Oikopleura dioica is emerging as a nonclassical animal model in the field of evolutionary developmental biology (a.k.a. evo-devo) especially attractive for investigating the impact of gene loss on the evolution of mechanisms of development. This is because this organism fulfills the...

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Detalhes bibliográficos
Autores: Ferrández-Roldán, Alfonso, Martí-Solans, Josep, Cañestro García, Cristian, Albalat Rodríguez, Ricard
Formato: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2019
País:España
Recursos:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/194908
Acesso em linha:https://hdl.handle.net/2445/194908
Access Level:acceso abierto
Palavra-chave:Cordats
Biologia del desenvolupament
Filogènia
Chordata
Developmental biology
Phylogeny
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spelling Oikopleura dioica: An Emergent Chordate Model to Study the Impact of Gene Loss on the Evolution of the Mechanisms of Development.Ferrández-Roldán, AlfonsoMartí-Solans, JosepCañestro García, CristianAlbalat Rodríguez, RicardCordatsBiologia del desenvolupamentFilogèniaChordataDevelopmental biologyPhylogenyThe urochordate Oikopleura dioica is emerging as a nonclassical animal model in the field of evolutionary developmental biology (a.k.a. evo-devo) especially attractive for investigating the impact of gene loss on the evolution of mechanisms of development. This is because this organism fulfills the requirements of an animal model (i.e., has a simple and accessible morphology, a short generation time and life span, and affordable culture in the laboratory and amenable experimental manipulation), but also because O. dioica occupies a key phylogenetic position to understand the diversification and origin of our own phylum, the chordates. During its evolution, O. dioica genome has suffered a drastic process of compaction, becoming the smallest known chordate genome, a process that has been accompanied by exacerbating amount of gene losses. Interestingly, however, despite the extensive gene losses, including entire regulatory pathways essential for the embryonic development of other chordates, O. dioica retains the typical chordate body plan. This unexpected situation led to the formulation of the so-called inverse paradox of evo-devo, that is, when a genetic diversity is able to maintain a phenotypic unity. This chapter reviews the biological features of O. dioica as a model animal, along with the current data on the evolution of its genes and genome. We pay special attention to the numerous examples of gene losses that have taken place during the evolution of this unique animal model, which is helping us to understand to which the limits of evo-devo can be pushed off.Springer Nature2023202320192023info:eu-repo/semantics/articleinfo:eu-repo/semantics/acceptedVersion42 p.application/pdfhttps://hdl.handle.net/2445/194908Articles publicats en revistes (Genètica, Microbiologia i Estadística)reponame:Recercat. Dipósit de la Recerca de Catalunyainstname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)InglésVersió postprint del document publicat a: https://doi.org/10.1007/978-3-030-23459-1_4Results and Problems in Cell Differentiation, 2019, vol. 68, p. 63-105https://doi.org/10.1007/978-3-030-23459-1_4(c) Springer Nature, 2019info:eu-repo/semantics/openAccessoai:recercat.cat:2445/1949082026-05-29T05:05:01Z
dc.title.none.fl_str_mv Oikopleura dioica: An Emergent Chordate Model to Study the Impact of Gene Loss on the Evolution of the Mechanisms of Development.
title Oikopleura dioica: An Emergent Chordate Model to Study the Impact of Gene Loss on the Evolution of the Mechanisms of Development.
spellingShingle Oikopleura dioica: An Emergent Chordate Model to Study the Impact of Gene Loss on the Evolution of the Mechanisms of Development.
Ferrández-Roldán, Alfonso
Cordats
Biologia del desenvolupament
Filogènia
Chordata
Developmental biology
Phylogeny
title_short Oikopleura dioica: An Emergent Chordate Model to Study the Impact of Gene Loss on the Evolution of the Mechanisms of Development.
title_full Oikopleura dioica: An Emergent Chordate Model to Study the Impact of Gene Loss on the Evolution of the Mechanisms of Development.
title_fullStr Oikopleura dioica: An Emergent Chordate Model to Study the Impact of Gene Loss on the Evolution of the Mechanisms of Development.
title_full_unstemmed Oikopleura dioica: An Emergent Chordate Model to Study the Impact of Gene Loss on the Evolution of the Mechanisms of Development.
title_sort Oikopleura dioica: An Emergent Chordate Model to Study the Impact of Gene Loss on the Evolution of the Mechanisms of Development.
dc.creator.none.fl_str_mv Ferrández-Roldán, Alfonso
Martí-Solans, Josep
Cañestro García, Cristian
Albalat Rodríguez, Ricard
author Ferrández-Roldán, Alfonso
author_facet Ferrández-Roldán, Alfonso
Martí-Solans, Josep
Cañestro García, Cristian
Albalat Rodríguez, Ricard
author_role author
author2 Martí-Solans, Josep
Cañestro García, Cristian
Albalat Rodríguez, Ricard
author2_role author
author
author
dc.subject.none.fl_str_mv Cordats
Biologia del desenvolupament
Filogènia
Chordata
Developmental biology
Phylogeny
topic Cordats
Biologia del desenvolupament
Filogènia
Chordata
Developmental biology
Phylogeny
description The urochordate Oikopleura dioica is emerging as a nonclassical animal model in the field of evolutionary developmental biology (a.k.a. evo-devo) especially attractive for investigating the impact of gene loss on the evolution of mechanisms of development. This is because this organism fulfills the requirements of an animal model (i.e., has a simple and accessible morphology, a short generation time and life span, and affordable culture in the laboratory and amenable experimental manipulation), but also because O. dioica occupies a key phylogenetic position to understand the diversification and origin of our own phylum, the chordates. During its evolution, O. dioica genome has suffered a drastic process of compaction, becoming the smallest known chordate genome, a process that has been accompanied by exacerbating amount of gene losses. Interestingly, however, despite the extensive gene losses, including entire regulatory pathways essential for the embryonic development of other chordates, O. dioica retains the typical chordate body plan. This unexpected situation led to the formulation of the so-called inverse paradox of evo-devo, that is, when a genetic diversity is able to maintain a phenotypic unity. This chapter reviews the biological features of O. dioica as a model animal, along with the current data on the evolution of its genes and genome. We pay special attention to the numerous examples of gene losses that have taken place during the evolution of this unique animal model, which is helping us to understand to which the limits of evo-devo can be pushed off.
publishDate 2019
dc.date.none.fl_str_mv 2019
2023
2023
2023
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/acceptedVersion
format article
status_str acceptedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/194908
url https://hdl.handle.net/2445/194908
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Versió postprint del document publicat a: https://doi.org/10.1007/978-3-030-23459-1_4
Results and Problems in Cell Differentiation, 2019, vol. 68, p. 63-105
https://doi.org/10.1007/978-3-030-23459-1_4
dc.rights.none.fl_str_mv (c) Springer Nature, 2019
info:eu-repo/semantics/openAccess
rights_invalid_str_mv (c) Springer Nature, 2019
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 42 p.
application/pdf
dc.publisher.none.fl_str_mv Springer Nature
publisher.none.fl_str_mv Springer Nature
dc.source.none.fl_str_mv Articles publicats en revistes (Genètica, Microbiologia i Estadística)
reponame:Recercat. Dipósit de la Recerca de Catalunya
instname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
instname_str Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
reponame_str Recercat. Dipósit de la Recerca de Catalunya
collection Recercat. Dipósit de la Recerca de Catalunya
repository.name.fl_str_mv
repository.mail.fl_str_mv
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