15th Post-ECTRIMS Meeting: a review of the latest developments presented at the 2022 ECTRIMS Congress (Part I)

Introduction. On 4 and 5 November 2022, Madrid hosted the 15th edition of the Post-ECTRIMS Meeting, where neurologists specialised in multiple sclerosis (MS) outlined the most relevant novelties presented at the 2022 ECTRIMS Congress, held in Amsterdam from 26 to 28 October. Aim. To synthesise the c...

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Detalhes bibliográficos
Autores: Fernandez, O, Montalban, X, Aguera, E, Aladro, Y, Alonso, A, Arroyo, R, Brieva, L, Calles, C, Costa-Frossard, L, Eichau, S, Garcia-Dominguez, JM, Hernandez, MA, Landete, L, Llufriu, MLS, Meca-Lallana, JE, Meca-Lallana, V, Mongay-Ochoa, N, Moral, E, Oreja-Guevara, C, Ramio-Torrenta, L, Tellez, N, Romero-Pinel, L, Rodriguez-Antiguedad, A
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2023
País:España
Recursos:Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
Repositorio:r-FISABIO. Repositorio Institucional de Producción Científica
OAI Identifier:oai:fisabio.fundanetsuite.com:p15585
Acesso em linha:https://fisabio.portalinvestigacion.com/publicaciones/15585
Access Level:acceso abierto
Palavra-chave:ECTRIMS
Image
Multiple sclerosis
Pathogenesis
Post-ECTRIMS
Remyelination
Descrição
Resumo:Introduction. On 4 and 5 November 2022, Madrid hosted the 15th edition of the Post-ECTRIMS Meeting, where neurologists specialised in multiple sclerosis (MS) outlined the most relevant novelties presented at the 2022 ECTRIMS Congress, held in Amsterdam from 26 to 28 October. Aim. To synthesise the content presented at the 15th edition of the Post-ECTRIMS Meeting, in an article broken down into two parts. Development. In this first part, the initial events involved in the onset of MS, the role played by lymphocytes and the migration of immune system cells into the central nervous system are presented. It describes emerging biomarkers in body fluids and imaging findings that are predictive of disease progression and useful in the differential diagnosis of MS. It also discusses advances in imaging techniques which, together with a better understanding of the agents involved in demyelination and remyelination processes, provide a basis for dealing with remyelination in the clinical setting. Finally, the mechanisms triggering the inflammatory reaction and neurodegeneration involved in MS pathology are reviewed.

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