Stereotactic radiosurgery for the treatment of recurrent high-grade gliomas: long-term follow-up
High-grade gliomas (HGG) are the most frequent primary central nervous system tumors; treatment of HCGs includes surgery and post-operative conformal radiotherapy associated with temozolomide (TMZ or procarbazine/lomustine/vincristine [PCV], specifically in patients with anaplastic oligodendroglioma...
| Autores: | , , , , , |
|---|---|
| Tipo de recurso: | artículo |
| Fecha de publicación: | 2019 |
| País: | España |
| Institución: | Universidad de Navarra |
| Repositorio: | Dadun. Depósito Académico Digital de la Universidad de Navarra |
| Idioma: | inglés |
| OAI Identifier: | oai:dadun.unav.edu:10171/62285 |
| Acceso en línea: | https://hdl.handle.net/10171/62285 |
| Access Level: | acceso abierto |
| Palabra clave: | Radiosurgery Cyberknife® Recurrent gliomas Ck-cyberknife Glioblastoma multiforme (gbm) Recurrent gbm Srs |
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Stereotactic radiosurgery for the treatment of recurrent high-grade gliomas: long-term follow-upSallabanda, K. (Kita)|||/items/c2893faa-8f39-419c-8a28-8e93aba7e50eYañez, L. (Loreto)|||/items/87e1e005-2728-4e8b-bdfe-5408173d5dd8Sallabanda, M. (Morena)|||/items/3668a543-920c-4305-bcfd-13a342c5c06cSantos, M. (Marcos)|||/items/cdb6609e-53ec-491b-acb4-adf7d945a9ddCalvo-Manuel, F.A. (Felipe Ángel)|||/items/b5d6c8b0-2e24-4372-a422-00af59a4cd3eMarsiglia, H. (Hugo)|||/items/57a84eee-bbee-4721-b798-075edc590d0aRadiosurgeryCyberknife®Recurrent gliomasCk-cyberknifeGlioblastoma multiforme (gbm)Recurrent gbmSrsHigh-grade gliomas (HGG) are the most frequent primary central nervous system tumors; treatment of HCGs includes surgery and post-operative conformal radiotherapy associated with temozolomide (TMZ or procarbazine/lomustine/vincristine [PCV], specifically in patients with anaplastic oligodendrogliomas or anaplastic oligoastrocytomas). However, recurrence is common. Re-irradiation has been utilized in this setting for years and remains a feasible option, although there is always a concern regarding toxicity. Modern high-precision conformal techniques, including stereotactic radiosurgery (SRS), could improve the therapeutic ratio by delivering high biologically equivalent doses while reducing high-dose radiotherapy (RT) to normal brain tissue. In this paper, we present the results obtained after prolonged follow-up in patients who underwent SRS as a treatment for recurrent high-grade gliomas at San Francisco Hospital in Madrid, Spain.Cureus, Inc.Dadun. Depósito Académico Digital Universidad de Navarra20212021-10-2720192019-01-0120192019-01-01journal articlehttp://purl.org/coar/resource_type/c_6501info:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/10171/62285reponame:Dadun. Depósito Académico Digital de la Universidad de Navarrainstname:Universidad de NavarraInglésengopen accesshttp://purl.org/coar/access_right/c_abf2info:eu-repo/semantics/openAccessoai:dadun.unav.edu:10171/622852026-06-21T12:47:57Z |
| dc.title.none.fl_str_mv |
Stereotactic radiosurgery for the treatment of recurrent high-grade gliomas: long-term follow-up |
| title |
Stereotactic radiosurgery for the treatment of recurrent high-grade gliomas: long-term follow-up |
| spellingShingle |
Stereotactic radiosurgery for the treatment of recurrent high-grade gliomas: long-term follow-up Sallabanda, K. (Kita)|||/items/c2893faa-8f39-419c-8a28-8e93aba7e50e Radiosurgery Cyberknife® Recurrent gliomas Ck-cyberknife Glioblastoma multiforme (gbm) Recurrent gbm Srs |
| title_short |
Stereotactic radiosurgery for the treatment of recurrent high-grade gliomas: long-term follow-up |
| title_full |
Stereotactic radiosurgery for the treatment of recurrent high-grade gliomas: long-term follow-up |
| title_fullStr |
Stereotactic radiosurgery for the treatment of recurrent high-grade gliomas: long-term follow-up |
| title_full_unstemmed |
Stereotactic radiosurgery for the treatment of recurrent high-grade gliomas: long-term follow-up |
| title_sort |
Stereotactic radiosurgery for the treatment of recurrent high-grade gliomas: long-term follow-up |
| dc.creator.none.fl_str_mv |
Sallabanda, K. (Kita)|||/items/c2893faa-8f39-419c-8a28-8e93aba7e50e Yañez, L. (Loreto)|||/items/87e1e005-2728-4e8b-bdfe-5408173d5dd8 Sallabanda, M. (Morena)|||/items/3668a543-920c-4305-bcfd-13a342c5c06c Santos, M. (Marcos)|||/items/cdb6609e-53ec-491b-acb4-adf7d945a9dd Calvo-Manuel, F.A. (Felipe Ángel)|||/items/b5d6c8b0-2e24-4372-a422-00af59a4cd3e Marsiglia, H. (Hugo)|||/items/57a84eee-bbee-4721-b798-075edc590d0a |
| author |
Sallabanda, K. (Kita)|||/items/c2893faa-8f39-419c-8a28-8e93aba7e50e |
| author_facet |
Sallabanda, K. (Kita)|||/items/c2893faa-8f39-419c-8a28-8e93aba7e50e Yañez, L. (Loreto)|||/items/87e1e005-2728-4e8b-bdfe-5408173d5dd8 Sallabanda, M. (Morena)|||/items/3668a543-920c-4305-bcfd-13a342c5c06c Santos, M. (Marcos)|||/items/cdb6609e-53ec-491b-acb4-adf7d945a9dd Calvo-Manuel, F.A. (Felipe Ángel)|||/items/b5d6c8b0-2e24-4372-a422-00af59a4cd3e Marsiglia, H. (Hugo)|||/items/57a84eee-bbee-4721-b798-075edc590d0a |
| author_role |
author |
| author2 |
Yañez, L. (Loreto)|||/items/87e1e005-2728-4e8b-bdfe-5408173d5dd8 Sallabanda, M. (Morena)|||/items/3668a543-920c-4305-bcfd-13a342c5c06c Santos, M. (Marcos)|||/items/cdb6609e-53ec-491b-acb4-adf7d945a9dd Calvo-Manuel, F.A. (Felipe Ángel)|||/items/b5d6c8b0-2e24-4372-a422-00af59a4cd3e Marsiglia, H. (Hugo)|||/items/57a84eee-bbee-4721-b798-075edc590d0a |
| author2_role |
author author author author author |
| dc.contributor.none.fl_str_mv |
Dadun. Depósito Académico Digital Universidad de Navarra |
| dc.subject.none.fl_str_mv |
Radiosurgery Cyberknife® Recurrent gliomas Ck-cyberknife Glioblastoma multiforme (gbm) Recurrent gbm Srs |
| topic |
Radiosurgery Cyberknife® Recurrent gliomas Ck-cyberknife Glioblastoma multiforme (gbm) Recurrent gbm Srs |
| description |
High-grade gliomas (HGG) are the most frequent primary central nervous system tumors; treatment of HCGs includes surgery and post-operative conformal radiotherapy associated with temozolomide (TMZ or procarbazine/lomustine/vincristine [PCV], specifically in patients with anaplastic oligodendrogliomas or anaplastic oligoastrocytomas). However, recurrence is common. Re-irradiation has been utilized in this setting for years and remains a feasible option, although there is always a concern regarding toxicity. Modern high-precision conformal techniques, including stereotactic radiosurgery (SRS), could improve the therapeutic ratio by delivering high biologically equivalent doses while reducing high-dose radiotherapy (RT) to normal brain tissue. In this paper, we present the results obtained after prolonged follow-up in patients who underwent SRS as a treatment for recurrent high-grade gliomas at San Francisco Hospital in Madrid, Spain. |
| publishDate |
2019 |
| dc.date.none.fl_str_mv |
2019 2019-01-01 2019 2019-01-01 2021 2021-10-27 |
| dc.type.none.fl_str_mv |
journal article http://purl.org/coar/resource_type/c_6501 |
| dc.type.openaire.fl_str_mv |
info:eu-repo/semantics/article |
| format |
article |
| dc.identifier.none.fl_str_mv |
https://hdl.handle.net/10171/62285 |
| url |
https://hdl.handle.net/10171/62285 |
| dc.language.none.fl_str_mv |
Inglés eng |
| language_invalid_str_mv |
Inglés |
| language |
eng |
| dc.rights.none.fl_str_mv |
open access http://purl.org/coar/access_right/c_abf2 |
| dc.rights.openaire.fl_str_mv |
info:eu-repo/semantics/openAccess |
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open access http://purl.org/coar/access_right/c_abf2 |
| eu_rights_str_mv |
openAccess |
| dc.format.none.fl_str_mv |
application/pdf |
| dc.publisher.none.fl_str_mv |
Cureus, Inc. |
| publisher.none.fl_str_mv |
Cureus, Inc. |
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reponame:Dadun. Depósito Académico Digital de la Universidad de Navarra instname:Universidad de Navarra |
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Universidad de Navarra |
| reponame_str |
Dadun. Depósito Académico Digital de la Universidad de Navarra |
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Dadun. Depósito Académico Digital de la Universidad de Navarra |
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1869417793760264192 |
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15.301603 |