Super-resolution microscopy: going live and going fast

Super-resolution microscopy is increasingly becoming an important tool for biological research, providing valuable information at the nanometer length scales inside cells and tissues. In the past decade numerous technological advancements have transformed superresolution microscopes into powerful to...

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Detalles Bibliográficos
Autor: Lakadamyali, Melike
Tipo de recurso: artículo
Fecha de publicación:2014
País:España
Institución:Universitat Politècnica de Catalunya (UPC)
Repositorio:UPCommons. Portal del coneixement obert de la UPC
Idioma:inglés
OAI Identifier:oai:upcommons.upc.edu:2117/109676
Acceso en línea:https://hdl.handle.net/2117/109676
Access Level:acceso abierto
Palabra clave:microscopy
Microscòpia
Àrees temàtiques de la UPC::Física
Descripción
Sumario:Super-resolution microscopy is increasingly becoming an important tool for biological research, providing valuable information at the nanometer length scales inside cells and tissues. In the past decade numerous technological advancements have transformed superresolution microscopes into powerful tools of discovery. While the first super-resolution images took several hours to acquire, recent progress has led to tremendous improvement in acquisition speed, enabling researchers to probe dynamic processes in living cells with unprecedented spatiotemporal resolution. This mini-review focuses on the recent developments in live-cell super-resolution microscopy and its biological applications.