Factors associated with the development of septic shock in patients with candidemia

Almost one third of the patients with candidemia develop septic shock. The understanding why some patients do and others do not develop septic shock is very limited. The objective of this study was to identify variables associated with septic shock development in a large population of patients with...

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Detalles Bibliográficos
Autores: Bassetti, Matteo|||0000-0002-0145-9740, Vena, Antonio|||0000-0002-0697-3992, Meroi, Marco, Cardozo, Celia, Cuervo, Guillermo|||0000-0002-7075-943X, Giacobbe, Daniele Roberto, Salavert, Miguel|||0000-0002-8571-2124, Merino, Paloma, Gioia, Francesca, Fernández-Ruiz, Mario, López Cortés, Luis Eduardo|||0000-0002-9347-527X, Almirante Gragera, Benito|||0000-0002-1189-2361, Escolà-Vergé, Laura|||0000-0002-5608-3090, Montejo, Miguel, Aguilar-Guisado, Manuela|||0000-0001-5639-9434, Puerta-Alcalde, Pedro|||0000-0003-2490-0217, Tasias, Mariona, Ruiz-Gaitán, Alba, González Romo, Fernando, Puig-Asensio, Mireia|||0000-0002-0722-2218, Marco, Francesc|||0000-0002-1863-6379, Pemán, Javier, Fortún, Jesús|||0000-0002-6959-5263, Aguado, José María|||0000-0002-9520-8255, Soriano, Alejandro, Carratalà, Jordi|||0000-0003-3209-2563, Garcia-Vidal, Carolina|||0000-0002-8915-0683, Valerio, Maricela, Sartor, Assunta, Bouza, Emilio, Munoz, Patricia|||0000-0001-5706-5583
Tipo de recurso: artículo
Fecha de publicación:2020
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:227688
Acceso en línea:https://ddd.uab.cat/record/227688
https://dx.doi.org/urn:doi:10.1186/s13054-020-2793-y
Access Level:acceso abierto
Palabra clave:Candidemia
Septic shock
Intra-abdominal candidiasis
Risk factors
Descripción
Sumario:Almost one third of the patients with candidemia develop septic shock. The understanding why some patients do and others do not develop septic shock is very limited. The objective of this study was to identify variables associated with septic shock development in a large population of patients with candidemia. A post hoc analysis was performed on two prospective, multicenter cohort of patients with candidemia from 12 hospitals in Spain and Italy. All episodes occurring from September 2016 to February 2018 were analyzed to assess variables associated with septic shock development defined according to The Third International Consensus Definition for Sepsis and Septic Shock (Sepsis-3). Of 317 candidemic patients, 99 (31.2%) presented septic shock attributable to candidemia. Multivariate logistic regression analysis identifies the following factors associated with septic shock development: age.

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