Quantitative Analysis of Different Foveal Avascular Zone Metrics in Healthy and Diabetic Subjects

The primary aim of this study was to assess the size and shape of the Foveal Avascular Zone (FAZ) in patients with type 2 diabetes mellitus compared to healthy subjects. The study used 80 OCTA images from the FAZID dataset. The FAZ size was measured by its area, perimeter, and maximum/minimum Feret...

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Autor: Sijilmassi, Ouafa
Tipo de documento: artigo
Data de publicação:2024
País:España
Recursos:Universidad Complutense de Madrid (UCM)
Repositório:Docta Complutense
Idioma:inglês
OAI Identifier:oai:docta.ucm.es:20.500.14352/132404
Acesso em linha:https://hdl.handle.net/20.500.14352/132404
Access Level:Acceso aberto
Palavra-chave:617.735:616.379-008.64
616.379-008.64
611.843
type 2 diabetes mellitus
diabetic retinopathy
FAZ
Oftalmología
Diagnóstico por imagen y medicina nuclear
3201.09 Oftalmología
2209 Óptica
2411.15 Fisiología de la Visión
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oai_identifier_str oai:docta.ucm.es:20.500.14352/132404
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repository_id_str
spelling Quantitative Analysis of Different Foveal Avascular Zone Metrics in Healthy and Diabetic SubjectsSijilmassi, Ouafa617.735:616.379-008.64616.379-008.64611.843type 2 diabetes mellitusdiabetic retinopathyFAZOftalmologíaDiagnóstico por imagen y medicina nuclear3201.09 Oftalmología2209 Óptica2411.15 Fisiología de la VisiónThe primary aim of this study was to assess the size and shape of the Foveal Avascular Zone (FAZ) in patients with type 2 diabetes mellitus compared to healthy subjects. The study used 80 OCTA images from the FAZID dataset. The FAZ size was measured by its area, perimeter, and maximum/minimum Feret diameters. The shape was assessed using the axial ratio, circularity, roundness, and solidity. These metrics were calculated automatically using Matlab® R2020b. Statistical analysis was performed using SPSS statistical software version 28.0, with a p-value of less than 0.01 considered significant. The results showed that the FAZ area was significantly larger in diabetic eyes (mean = 0.50 mm2) compared to control eyes (mean = 0.37 mm2), with a p-value of less than 0.01. Both the maximum and minimum diameters of the FAZ were also significantly larger in diabetic groups compared to the control group. Parameters associated with FAZ’s shape were significantly smaller in the diabetic groups than in the control group, except for the axial ratio. The main finding of this study is that diabetic eyes without clinically detectable diabetic retinopathy exhibit morphological changes and irregularities at the FAZ border.MDPIUniversidad Complutense de Madrid20242024-06-3020242024-06-30journal articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/20.500.14352/132404reponame:Docta Complutenseinstname:Universidad Complutense de Madrid (UCM)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2Attribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:docta.ucm.es:20.500.14352/1324042026-06-02T12:44:21Z
dc.title.none.fl_str_mv Quantitative Analysis of Different Foveal Avascular Zone Metrics in Healthy and Diabetic Subjects
title Quantitative Analysis of Different Foveal Avascular Zone Metrics in Healthy and Diabetic Subjects
spellingShingle Quantitative Analysis of Different Foveal Avascular Zone Metrics in Healthy and Diabetic Subjects
Sijilmassi, Ouafa
617.735:616.379-008.64
616.379-008.64
611.843
type 2 diabetes mellitus
diabetic retinopathy
FAZ
Oftalmología
Diagnóstico por imagen y medicina nuclear
3201.09 Oftalmología
2209 Óptica
2411.15 Fisiología de la Visión
title_short Quantitative Analysis of Different Foveal Avascular Zone Metrics in Healthy and Diabetic Subjects
title_full Quantitative Analysis of Different Foveal Avascular Zone Metrics in Healthy and Diabetic Subjects
title_fullStr Quantitative Analysis of Different Foveal Avascular Zone Metrics in Healthy and Diabetic Subjects
title_full_unstemmed Quantitative Analysis of Different Foveal Avascular Zone Metrics in Healthy and Diabetic Subjects
title_sort Quantitative Analysis of Different Foveal Avascular Zone Metrics in Healthy and Diabetic Subjects
dc.creator.none.fl_str_mv Sijilmassi, Ouafa
author Sijilmassi, Ouafa
author_facet Sijilmassi, Ouafa
author_role author
dc.contributor.none.fl_str_mv Universidad Complutense de Madrid
dc.subject.none.fl_str_mv 617.735:616.379-008.64
616.379-008.64
611.843
type 2 diabetes mellitus
diabetic retinopathy
FAZ
Oftalmología
Diagnóstico por imagen y medicina nuclear
3201.09 Oftalmología
2209 Óptica
2411.15 Fisiología de la Visión
topic 617.735:616.379-008.64
616.379-008.64
611.843
type 2 diabetes mellitus
diabetic retinopathy
FAZ
Oftalmología
Diagnóstico por imagen y medicina nuclear
3201.09 Oftalmología
2209 Óptica
2411.15 Fisiología de la Visión
description The primary aim of this study was to assess the size and shape of the Foveal Avascular Zone (FAZ) in patients with type 2 diabetes mellitus compared to healthy subjects. The study used 80 OCTA images from the FAZID dataset. The FAZ size was measured by its area, perimeter, and maximum/minimum Feret diameters. The shape was assessed using the axial ratio, circularity, roundness, and solidity. These metrics were calculated automatically using Matlab® R2020b. Statistical analysis was performed using SPSS statistical software version 28.0, with a p-value of less than 0.01 considered significant. The results showed that the FAZ area was significantly larger in diabetic eyes (mean = 0.50 mm2) compared to control eyes (mean = 0.37 mm2), with a p-value of less than 0.01. Both the maximum and minimum diameters of the FAZ were also significantly larger in diabetic groups compared to the control group. Parameters associated with FAZ’s shape were significantly smaller in the diabetic groups than in the control group, except for the axial ratio. The main finding of this study is that diabetic eyes without clinically detectable diabetic retinopathy exhibit morphological changes and irregularities at the FAZ border.
publishDate 2024
dc.date.none.fl_str_mv 2024
2024-06-30
2024
2024-06-30
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://hdl.handle.net/20.500.14352/132404
url https://hdl.handle.net/20.500.14352/132404
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution 4.0 International
http://creativecommons.org/licenses/by/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution 4.0 International
http://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:Docta Complutense
instname:Universidad Complutense de Madrid (UCM)
instname_str Universidad Complutense de Madrid (UCM)
reponame_str Docta Complutense
collection Docta Complutense
repository.name.fl_str_mv
repository.mail.fl_str_mv
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