Microscale thermophoresis experiments on Rap-pheromone interactions

Dose-response slopes for the interaction between Rap3T and pheromone variants (RRGHTA, SRGHTS, RRGHTAS, RGHTS, and Imat13T) and Rap105 with pheromone ERPVGT. Notice the sigmoidal and non-hyperbolic curve, indicating a cooperative effect on peptide binding

Bibliographic Details
Authors: Felipe-Ruiz, Alonso, Zamora-Caballero, Sara, Bendori, Shira Omer, Penadés, José R., Eldar, Avigdor, Marina, Alberto
Format: conjunto de datos
Status:Published version
Publication Date:2024
Country:España
Institution:Consejo Superior de Investigaciones Científicas (CSIC)
Repository:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/371644
Online Access:http://hdl.handle.net/10261/371644
Access Level:Open access
Keyword:Small signaling molecules
Produce identical structural
Opening new possibilities
Exhibit different types
Microbial social behaviors
Bacillus subtilis
Prevalent qs systems
Systems playing
Coordinating behaviors
Bacillota
Varying affinities
Several cases
Secreted oligopeptides
RRNPPA family
Results reveal
Receptor specificity
Quorum sensing
qs communication
Produced pheromones
Processes governing
Pheromone duplication
Mediating communication
Intricate nature
Functional significance
Functional activities
Extracellular proteolysis
Extracellular proteases
Diversify peptide
Changing environments
Central role
Biological responses
Bacteriophages infecting
Bacterial interactions
Active pheromones
Quorum Sensing
https://www.ncbi.nlm.nih.gov/mesh/68053038
https://www.ncbi.nlm.nih.gov/mesh/68001412
Description
Summary:Dose-response slopes for the interaction between Rap3T and pheromone variants (RRGHTA, SRGHTS, RRGHTAS, RGHTS, and Imat13T) and Rap105 with pheromone ERPVGT. Notice the sigmoidal and non-hyperbolic curve, indicating a cooperative effect on peptide binding

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