Multiscale modeling of bone tissue Mechanobiology

Mechanical environment has a crucial role in our organism at the different levels, ranging from cells to tissues and our own organs. This regulatory role is especially relevant for bones, given their importance as load-transmitting elements that allow the movement of our body as well as the protecti...

ver descrição completa

Detalhes bibliográficos
Autores: García-Aznar, José Manuel, Nasello, Gabriele, Hervas-Raluy, Silvia, Pérez Ansón, María de los Ángeles, Gómez-Benito, María José
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2021
País:España
Recursos:Universidad de Zaragoza
Repositorio:Zaguán. Repositorio Digital de la Universidad de Zaragoza
OAI Identifier:oai:zaguan.unizar.es:106162
Acesso em linha:http://zaguan.unizar.es/record/106162
Access Level:acceso abierto
id ES_b80dadb9c6ee3e9b460d38ffb080f628
oai_identifier_str oai:zaguan.unizar.es:106162
network_acronym_str ES
network_name_str España
repository_id_str
spelling Multiscale modeling of bone tissue MechanobiologyGarcía-Aznar, José ManuelNasello, GabrieleHervas-Raluy, SilviaPérez Ansón, María de los ÁngelesGómez-Benito, María JoséMechanical environment has a crucial role in our organism at the different levels, ranging from cells to tissues and our own organs. This regulatory role is especially relevant for bones, given their importance as load-transmitting elements that allow the movement of our body as well as the protection of vital organs from load impacts. Therefore bone, as living tissue, is continuously adapting its properties, shape and repairing itself, being the mechanical loads one of the main regulatory stimuli that modulate this adaptive behavior. Here we review some key results of bone mechanobiology from computational models, describing the effect that changes associated to the mechanical environment induce in bone response, implant design and scaffold-driven bone regeneration.2021info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://zaguan.unizar.es/record/106162reponame:Zaguán. Repositorio Digital de la Universidad de Zaragozainstname:Universidad de ZaragozaInglésinfo:eu-repo/grantAgreement/EC/H2020/722535This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement No H2020 722535-CuraBoneinfo:eu-repo/grantAgreement/ES/MICINN/RTI2018-094494-B-C21info:eu-repo/grantAgreement/ES/MINECO/DPI2017-84780-C2-1-Rinfo:eu-repo/semantics/openAccessoai:zaguan.unizar.es:1061622026-05-29T13:59:51Z
dc.title.none.fl_str_mv Multiscale modeling of bone tissue Mechanobiology
title Multiscale modeling of bone tissue Mechanobiology
spellingShingle Multiscale modeling of bone tissue Mechanobiology
García-Aznar, José Manuel
title_short Multiscale modeling of bone tissue Mechanobiology
title_full Multiscale modeling of bone tissue Mechanobiology
title_fullStr Multiscale modeling of bone tissue Mechanobiology
title_full_unstemmed Multiscale modeling of bone tissue Mechanobiology
title_sort Multiscale modeling of bone tissue Mechanobiology
dc.creator.none.fl_str_mv García-Aznar, José Manuel
Nasello, Gabriele
Hervas-Raluy, Silvia
Pérez Ansón, María de los Ángeles
Gómez-Benito, María José
author García-Aznar, José Manuel
author_facet García-Aznar, José Manuel
Nasello, Gabriele
Hervas-Raluy, Silvia
Pérez Ansón, María de los Ángeles
Gómez-Benito, María José
author_role author
author2 Nasello, Gabriele
Hervas-Raluy, Silvia
Pérez Ansón, María de los Ángeles
Gómez-Benito, María José
author2_role author
author
author
author
description Mechanical environment has a crucial role in our organism at the different levels, ranging from cells to tissues and our own organs. This regulatory role is especially relevant for bones, given their importance as load-transmitting elements that allow the movement of our body as well as the protection of vital organs from load impacts. Therefore bone, as living tissue, is continuously adapting its properties, shape and repairing itself, being the mechanical loads one of the main regulatory stimuli that modulate this adaptive behavior. Here we review some key results of bone mechanobiology from computational models, describing the effect that changes associated to the mechanical environment induce in bone response, implant design and scaffold-driven bone regeneration.
publishDate 2021
dc.date.none.fl_str_mv 2021
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://zaguan.unizar.es/record/106162
url http://zaguan.unizar.es/record/106162
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv info:eu-repo/grantAgreement/EC/H2020/722535
This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement No H2020 722535-CuraBone
info:eu-repo/grantAgreement/ES/MICINN/RTI2018-094494-B-C21
info:eu-repo/grantAgreement/ES/MINECO/DPI2017-84780-C2-1-R
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv
publisher.none.fl_str_mv
dc.source.none.fl_str_mv reponame:Zaguán. Repositorio Digital de la Universidad de Zaragoza
instname:Universidad de Zaragoza
instname_str Universidad de Zaragoza
reponame_str Zaguán. Repositorio Digital de la Universidad de Zaragoza
collection Zaguán. Repositorio Digital de la Universidad de Zaragoza
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869417598762876928
score 15,300719

Registos relacionados