Effects of a tailored exercise intervention in acutely hospitalized diabetic oldest old adults: An ancillary analysis

Objective: To analyze the effects of a tailored exercise intervention in acutely hospitalized oldest old diabetic patients. Research design and methods: This is an ancillary analysis of a randomized controlled trial. 103 acutely hospitalized older adults (mean age ~87 years) with type II diabetes we...

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Autores: Martínez Velilla, Nicolás, Valenzuela Ruiz, Pedro Luis, Sáez de Asteasu, Mikel L., Zambom Ferraresi, Fabricio, Ramírez Vélez, Robinson, García Hermoso, Antonio, Librero López, Julián, Gorricho, Javier, Lucía Mulas, Alejandro, Izquierdo Gabarren, Mikel, Et al.
Tipo de recurso: artículo
Fecha de publicación:2021
País:España
Institución:Universidad Europea (UEM)
Repositorio:ABACUS. Repositorio de Producción Científica
Idioma:inglés
OAI Identifier:oai:abacus.universidadeuropea.com:11268/9676
Acceso en línea:http://hdl.handle.net/11268/9676
Access Level:acceso abierto
Palabra clave:Diabetes
Ejercicio físico
Ancianos
Metabolismo
Enfermedad
Deporte
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spelling Effects of a tailored exercise intervention in acutely hospitalized diabetic oldest old adults: An ancillary analysisMartínez Velilla, NicolásValenzuela Ruiz, Pedro LuisSáez de Asteasu, Mikel L.Zambom Ferraresi, FabricioRamírez Vélez, RobinsonGarcía Hermoso, AntonioLibrero López, JuliánGorricho, JavierLucía Mulas, AlejandroIzquierdo Gabarren, MikelEt al.DiabetesEjercicio físicoAncianosMetabolismoEnfermedadDeporteObjective: To analyze the effects of a tailored exercise intervention in acutely hospitalized oldest old diabetic patients. Research design and methods: This is an ancillary analysis of a randomized controlled trial. 103 acutely hospitalized older adults (mean age ~87 years) with type II diabetes were randomized to an intervention (exercise, n=54) or control group (usual care, n=49). The primary endpoint was change in functional status from baseline to hospital discharge as assessed with the Barthel index and the Short Physical Performance Battery [SSPB]. Secondary endpoints comprised cognitive function and mood status, quality of life (QoL), incidence of delirium, and handgrip strength. Exercise-related side effects, length of hospital stay and incidence of falls during hospitalization we also assessed, as well as transfer to nursing homes, hospital readmission and mortality during a 3-month follow-up. Results: The median length of stay was 8 days (interquartile range, 4) for both groups. The intervention was safe and provided significant benefits over usual care on SPPB (2.7 [95% confidence interval 1.8, 3.5]) and Barthel Index (8.5 [95% CI: 3.9, 13.1]), as well as on other secondary endpoints such as cognitive status, depression, QoL and handgrip strength (all p<0.05). No significant between-group differences were found for the remainder of secondary endpoints. Conclusions: An inhospital individualized multicomponent exercise intervention was safe and effective for the prevention of functional and cognitive decline in acutely hospitalized diabetic oldest old patients, although it had no influence on other endpoints assessed in during hospitalization of at 3-month follow-up after discharge.ClinicalTrials.gov identifier: NCT02300896.20212021-01-1420212021-01-0120212021-01-01journal articlehttp://purl.org/coar/resource_type/c_6501info:eu-repo/semantics/articlehttp://hdl.handle.net/11268/9676reponame:ABACUS. Repositorio de Producción Científicainstname:Universidad Europea (UEM)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2Attribution-NonCommercial-NoDerivatives 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:abacus.universidadeuropea.com:11268/96762026-06-11T12:41:27Z
dc.title.none.fl_str_mv Effects of a tailored exercise intervention in acutely hospitalized diabetic oldest old adults: An ancillary analysis
title Effects of a tailored exercise intervention in acutely hospitalized diabetic oldest old adults: An ancillary analysis
spellingShingle Effects of a tailored exercise intervention in acutely hospitalized diabetic oldest old adults: An ancillary analysis
Martínez Velilla, Nicolás
Diabetes
Ejercicio físico
Ancianos
Metabolismo
Enfermedad
Deporte
title_short Effects of a tailored exercise intervention in acutely hospitalized diabetic oldest old adults: An ancillary analysis
title_full Effects of a tailored exercise intervention in acutely hospitalized diabetic oldest old adults: An ancillary analysis
title_fullStr Effects of a tailored exercise intervention in acutely hospitalized diabetic oldest old adults: An ancillary analysis
title_full_unstemmed Effects of a tailored exercise intervention in acutely hospitalized diabetic oldest old adults: An ancillary analysis
title_sort Effects of a tailored exercise intervention in acutely hospitalized diabetic oldest old adults: An ancillary analysis
dc.creator.none.fl_str_mv Martínez Velilla, Nicolás
Valenzuela Ruiz, Pedro Luis
Sáez de Asteasu, Mikel L.
Zambom Ferraresi, Fabricio
Ramírez Vélez, Robinson
García Hermoso, Antonio
Librero López, Julián
Gorricho, Javier
Lucía Mulas, Alejandro
Izquierdo Gabarren, Mikel
Et al.
author Martínez Velilla, Nicolás
author_facet Martínez Velilla, Nicolás
Valenzuela Ruiz, Pedro Luis
Sáez de Asteasu, Mikel L.
Zambom Ferraresi, Fabricio
Ramírez Vélez, Robinson
García Hermoso, Antonio
Librero López, Julián
Gorricho, Javier
Lucía Mulas, Alejandro
Izquierdo Gabarren, Mikel
Et al.
author_role author
author2 Valenzuela Ruiz, Pedro Luis
Sáez de Asteasu, Mikel L.
Zambom Ferraresi, Fabricio
Ramírez Vélez, Robinson
García Hermoso, Antonio
Librero López, Julián
Gorricho, Javier
Lucía Mulas, Alejandro
Izquierdo Gabarren, Mikel
Et al.
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv
dc.subject.none.fl_str_mv Diabetes
Ejercicio físico
Ancianos
Metabolismo
Enfermedad
Deporte
topic Diabetes
Ejercicio físico
Ancianos
Metabolismo
Enfermedad
Deporte
description Objective: To analyze the effects of a tailored exercise intervention in acutely hospitalized oldest old diabetic patients. Research design and methods: This is an ancillary analysis of a randomized controlled trial. 103 acutely hospitalized older adults (mean age ~87 years) with type II diabetes were randomized to an intervention (exercise, n=54) or control group (usual care, n=49). The primary endpoint was change in functional status from baseline to hospital discharge as assessed with the Barthel index and the Short Physical Performance Battery [SSPB]. Secondary endpoints comprised cognitive function and mood status, quality of life (QoL), incidence of delirium, and handgrip strength. Exercise-related side effects, length of hospital stay and incidence of falls during hospitalization we also assessed, as well as transfer to nursing homes, hospital readmission and mortality during a 3-month follow-up. Results: The median length of stay was 8 days (interquartile range, 4) for both groups. The intervention was safe and provided significant benefits over usual care on SPPB (2.7 [95% confidence interval 1.8, 3.5]) and Barthel Index (8.5 [95% CI: 3.9, 13.1]), as well as on other secondary endpoints such as cognitive status, depression, QoL and handgrip strength (all p<0.05). No significant between-group differences were found for the remainder of secondary endpoints. Conclusions: An inhospital individualized multicomponent exercise intervention was safe and effective for the prevention of functional and cognitive decline in acutely hospitalized diabetic oldest old patients, although it had no influence on other endpoints assessed in during hospitalization of at 3-month follow-up after discharge.ClinicalTrials.gov identifier: NCT02300896.
publishDate 2021
dc.date.none.fl_str_mv 2021
2021-01-14
2021
2021-01-01
2021
2021-01-01
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv http://hdl.handle.net/11268/9676
url http://hdl.handle.net/11268/9676
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial-NoDerivatives 4.0 Internacional
http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial-NoDerivatives 4.0 Internacional
http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv reponame:ABACUS. Repositorio de Producción Científica
instname:Universidad Europea (UEM)
instname_str Universidad Europea (UEM)
reponame_str ABACUS. Repositorio de Producción Científica
collection ABACUS. Repositorio de Producción Científica
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,300719

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