Association between myocarditis and antipsychotics other than clozapine: A systematic literature review and a pharmacovigilance study using VigiBase
Pharmacovigilance studies have definitely established that clozapine can cause myocarditis. Two published reviews suggested that on rare occasions other antipsychotics may induce myocarditis. This review explored myocarditis associated with antipsychotics other than clozapine by conducting a systema...
| Authors: | , , , |
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| Format: | article |
| Publication Date: | 2022 |
| Country: | España |
| Institution: | Universidad de La Laguna (ULL) |
| Repository: | RIULL. Repositorio Institucional de la Universidad de La Laguna |
| OAI Identifier: | oai:riull.ull.es:915/39574 |
| Online Access: | http://riull.ull.es/xmlui/handle/915/39574 |
| Access Level: | Open access |
| Keyword: | Antipsychotic agents Administration and dosage Adverse effects Poisoning Toxicity Drug effects Myocarditis Chemically induced Olanzapine Quetiapine |
| Summary: | Pharmacovigilance studies have definitely established that clozapine can cause myocarditis. Two published reviews suggested that on rare occasions other antipsychotics may induce myocarditis. This review explored myocarditis associated with antipsychotics other than clozapine by conducting a systematic search of the literature and critically analyzing the current data in VigiBase compared to the data on clozapine-associated myocarditis. VigiBase is the World Health Organization’s global pharmacovigilance database which uses as a statistical signal for associations a logarithmic measure of disproportionality called the information component (IC) |
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