Association between myocarditis and antipsychotics other than clozapine: A systematic literature review and a pharmacovigilance study using VigiBase

Pharmacovigilance studies have definitely established that clozapine can cause myocarditis. Two published reviews suggested that on rare occasions other antipsychotics may induce myocarditis. This review explored myocarditis associated with antipsychotics other than clozapine by conducting a systema...

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Detalles Bibliográficos
Autores: Cuevas Castresana, Carlos de las, Rohde, Christopher, León, José de, Sanz Álvarez, Emilio José
Tipo de recurso: artículo
Fecha de publicación:2022
País:España
Institución:Universidad de La Laguna (ULL)
Repositorio:RIULL. Repositorio Institucional de la Universidad de La Laguna
OAI Identifier:oai:riull.ull.es:915/39574
Acceso en línea:http://riull.ull.es/xmlui/handle/915/39574
Access Level:acceso abierto
Palabra clave:Antipsychotic agents
Administration and dosage
Adverse effects
Poisoning
Toxicity
Drug effects
Myocarditis
Chemically induced
Olanzapine
Quetiapine
Descripción
Sumario:Pharmacovigilance studies have definitely established that clozapine can cause myocarditis. Two published reviews suggested that on rare occasions other antipsychotics may induce myocarditis. This review explored myocarditis associated with antipsychotics other than clozapine by conducting a systematic search of the literature and critically analyzing the current data in VigiBase compared to the data on clozapine-associated myocarditis. VigiBase is the World Health Organization’s global pharmacovigilance database which uses as a statistical signal for associations a logarithmic measure of disproportionality called the information component (IC)