Oligonucleotide therapeutics. A long and windy road towards future medicines

Oligonucleotide-based therapeutics is considered a major drug development area for the upcoming years. Research in this field has led to the discovery of new mechanisms for the regulation of genes expression. In addition, it has allowed the development of new strategies for the preparation of drugs...

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Detalles Bibliográficos
Autores: Eritja Casadellà, Ramón, Fàbrega, Carme
Tipo de recurso: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2023
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/335958
Acceso en línea:http://hdl.handle.net/10261/335958
Access Level:acceso abierto
Palabra clave:Oligonucleotide-based therapeutics
http://metadata.un.org/sdg/3
Ensure healthy lives and promote well-being for all at all ages
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spelling Oligonucleotide therapeutics. A long and windy road towards future medicinesEritja Casadellà, RamónFàbrega, CarmeOligonucleotide-based therapeuticshttp://metadata.un.org/sdg/3Ensure healthy lives and promote well-being for all at all agesOligonucleotide-based therapeutics is considered a major drug development area for the upcoming years. Research in this field has led to the discovery of new mechanisms for the regulation of genes expression. In addition, it has allowed the development of new strategies for the preparation of drugs that act at the level of gene expression, modulating the production of proteins responsible for causing diseases. However, it took huge effort that last around 30-40 years to demonstrate the validity of this approach. In this manuscript, we will go over the main developments of the area.Peer reviewedConsejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]202320232023info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501Postprintinfo:eu-repo/semantics/acceptedVersionhttp://hdl.handle.net/10261/335958reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Ingléshttps://www.teknoscienze.com/tks_article/oligonucleotide-therapeutics-a-long-and-windy-road-towards-future-medicines/Síinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/3359582026-05-22T06:33:51Z
dc.title.none.fl_str_mv Oligonucleotide therapeutics. A long and windy road towards future medicines
title Oligonucleotide therapeutics. A long and windy road towards future medicines
spellingShingle Oligonucleotide therapeutics. A long and windy road towards future medicines
Eritja Casadellà, Ramón
Oligonucleotide-based therapeutics
http://metadata.un.org/sdg/3
Ensure healthy lives and promote well-being for all at all ages
title_short Oligonucleotide therapeutics. A long and windy road towards future medicines
title_full Oligonucleotide therapeutics. A long and windy road towards future medicines
title_fullStr Oligonucleotide therapeutics. A long and windy road towards future medicines
title_full_unstemmed Oligonucleotide therapeutics. A long and windy road towards future medicines
title_sort Oligonucleotide therapeutics. A long and windy road towards future medicines
dc.creator.none.fl_str_mv Eritja Casadellà, Ramón
Fàbrega, Carme
author Eritja Casadellà, Ramón
author_facet Eritja Casadellà, Ramón
Fàbrega, Carme
author_role author
author2 Fàbrega, Carme
author2_role author
dc.contributor.none.fl_str_mv Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]
dc.subject.none.fl_str_mv Oligonucleotide-based therapeutics
http://metadata.un.org/sdg/3
Ensure healthy lives and promote well-being for all at all ages
topic Oligonucleotide-based therapeutics
http://metadata.un.org/sdg/3
Ensure healthy lives and promote well-being for all at all ages
description Oligonucleotide-based therapeutics is considered a major drug development area for the upcoming years. Research in this field has led to the discovery of new mechanisms for the regulation of genes expression. In addition, it has allowed the development of new strategies for the preparation of drugs that act at the level of gene expression, modulating the production of proteins responsible for causing diseases. However, it took huge effort that last around 30-40 years to demonstrate the validity of this approach. In this manuscript, we will go over the main developments of the area.
publishDate 2023
dc.date.none.fl_str_mv 2023
2023
2023
dc.type.none.fl_str_mv info:eu-repo/semantics/article
http://purl.org/coar/resource_type/c_6501
Postprint
info:eu-repo/semantics/acceptedVersion
format article
status_str acceptedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/335958
url http://hdl.handle.net/10261/335958
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv https://www.teknoscienze.com/tks_article/oligonucleotide-therapeutics-a-long-and-windy-road-towards-future-medicines/
Sí
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
repository.name.fl_str_mv
repository.mail.fl_str_mv
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