Exposure to heavy metal-contaminated sediments disrupts gene expression, lipid profile, and life history traits in the midge Chironomus riparius

Despite the concern about anthropogenic heavy metal accumulation, there remain few multi-level ecotoxicological studies to evaluate their effects in fluvial ecosystems. The toxicity of field-collected sediments exhibiting a gradient of heavy metal contamination (Cd, Pb, and Zn) was assessed in Chiro...

ver descrição completa

Detalhes bibliográficos
Autores: Arambourou, Hélène, Llorente, Lola, Moreno-Ocio, Iñigo, Herrero, Oscar, Barata Martí, Carlos, Fuertes, Inmaculada
Formato: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2020
País:España
Recursos:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/202692
Acesso em linha:http://hdl.handle.net/10261/202692
Access Level:acceso abierto
Palavra-chave:Lipidomic
Endocrine disruption
Integrative approach
Larval development
Shape markers
Transcriptional alterations
id ES_b6f78751ab249cfccfdb795d7e59cdd2
oai_identifier_str oai:digital.csic.es:10261/202692
network_acronym_str ES
network_name_str España
repository_id_str
spelling Exposure to heavy metal-contaminated sediments disrupts gene expression, lipid profile, and life history traits in the midge Chironomus ripariusArambourou, HélèneLlorente, LolaMoreno-Ocio, IñigoHerrero, OscarBarata Martí, CarlosFuertes, InmaculadaLipidomicEndocrine disruptionIntegrative approachLarval developmentShape markersTranscriptional alterationsDespite the concern about anthropogenic heavy metal accumulation, there remain few multi-level ecotoxicological studies to evaluate their effects in fluvial ecosystems. The toxicity of field-collected sediments exhibiting a gradient of heavy metal contamination (Cd, Pb, and Zn) was assessed in Chironomus riparius. For this purpose, larvae were exposed throughout their entire life cycle to these sediments, and toxic effects were measured at different levels of biological organization, from the molecular (lipidomic analysis and transcriptional profile) to the whole organism response (respiration rate, shape markers, and emergence rate). Alterations in the activity of relevant genes, as well as an increase of storage lipids and decrease in membrane fluidity, were detected in larvae exposed to the most contaminated sediments. Moreover, reduced larval and adult mass, decrease of larval respiration rate, and delayed emergence were observed, along with increased mentum and mandible size in larvae and decreased wing loading in adults. This study points out the deleterious effects of heavy metal exposure at various levels of biological organization and provides some clues regarding the mode of toxic action. This integrative approach provides new insights into the multi-level effects on aquatic insects exposed to heavy metal mixtures in field sediments, providing useful tools for ecological risk assessment in freshwater ecosystems. © 2019 Elsevier LtdThe professional editing service NB Revisions was used for technical preparation of the text prior to submission.Peer reviewedElsevierBarata Martí, Carlos [0000-0002-3360-0729]Fuertes, Inmaculada [0000-0001-8415-7993]Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]202020202020info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501Postprintinfo:eu-repo/semantics/acceptedVersionhttp://hdl.handle.net/10261/202692reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Ingléshttps://doi.org/10.1016/j.watres.2019.115165Síinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/2026922026-05-22T06:33:51Z
dc.title.none.fl_str_mv Exposure to heavy metal-contaminated sediments disrupts gene expression, lipid profile, and life history traits in the midge Chironomus riparius
title Exposure to heavy metal-contaminated sediments disrupts gene expression, lipid profile, and life history traits in the midge Chironomus riparius
spellingShingle Exposure to heavy metal-contaminated sediments disrupts gene expression, lipid profile, and life history traits in the midge Chironomus riparius
Arambourou, Hélène
Lipidomic
Endocrine disruption
Integrative approach
Larval development
Shape markers
Transcriptional alterations
title_short Exposure to heavy metal-contaminated sediments disrupts gene expression, lipid profile, and life history traits in the midge Chironomus riparius
title_full Exposure to heavy metal-contaminated sediments disrupts gene expression, lipid profile, and life history traits in the midge Chironomus riparius
title_fullStr Exposure to heavy metal-contaminated sediments disrupts gene expression, lipid profile, and life history traits in the midge Chironomus riparius
title_full_unstemmed Exposure to heavy metal-contaminated sediments disrupts gene expression, lipid profile, and life history traits in the midge Chironomus riparius
title_sort Exposure to heavy metal-contaminated sediments disrupts gene expression, lipid profile, and life history traits in the midge Chironomus riparius
dc.creator.none.fl_str_mv Arambourou, Hélène
Llorente, Lola
Moreno-Ocio, Iñigo
Herrero, Oscar
Barata Martí, Carlos
Fuertes, Inmaculada
author Arambourou, Hélène
author_facet Arambourou, Hélène
Llorente, Lola
Moreno-Ocio, Iñigo
Herrero, Oscar
Barata Martí, Carlos
Fuertes, Inmaculada
author_role author
author2 Llorente, Lola
Moreno-Ocio, Iñigo
Herrero, Oscar
Barata Martí, Carlos
Fuertes, Inmaculada
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Barata Martí, Carlos [0000-0002-3360-0729]
Fuertes, Inmaculada [0000-0001-8415-7993]
Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]
dc.subject.none.fl_str_mv Lipidomic
Endocrine disruption
Integrative approach
Larval development
Shape markers
Transcriptional alterations
topic Lipidomic
Endocrine disruption
Integrative approach
Larval development
Shape markers
Transcriptional alterations
description Despite the concern about anthropogenic heavy metal accumulation, there remain few multi-level ecotoxicological studies to evaluate their effects in fluvial ecosystems. The toxicity of field-collected sediments exhibiting a gradient of heavy metal contamination (Cd, Pb, and Zn) was assessed in Chironomus riparius. For this purpose, larvae were exposed throughout their entire life cycle to these sediments, and toxic effects were measured at different levels of biological organization, from the molecular (lipidomic analysis and transcriptional profile) to the whole organism response (respiration rate, shape markers, and emergence rate). Alterations in the activity of relevant genes, as well as an increase of storage lipids and decrease in membrane fluidity, were detected in larvae exposed to the most contaminated sediments. Moreover, reduced larval and adult mass, decrease of larval respiration rate, and delayed emergence were observed, along with increased mentum and mandible size in larvae and decreased wing loading in adults. This study points out the deleterious effects of heavy metal exposure at various levels of biological organization and provides some clues regarding the mode of toxic action. This integrative approach provides new insights into the multi-level effects on aquatic insects exposed to heavy metal mixtures in field sediments, providing useful tools for ecological risk assessment in freshwater ecosystems. © 2019 Elsevier Ltd
publishDate 2020
dc.date.none.fl_str_mv 2020
2020
2020
dc.type.none.fl_str_mv info:eu-repo/semantics/article
http://purl.org/coar/resource_type/c_6501
Postprint
info:eu-repo/semantics/acceptedVersion
format article
status_str acceptedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/202692
url http://hdl.handle.net/10261/202692
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv https://doi.org/10.1016/j.watres.2019.115165
Sí
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869417490110480384
score 15,811543

Registos relacionados