Screening of modular sugar derived phosphite-based ligand libraries for m-catalyzed reactions. A green approach to catalysts discovery
The growing demand for enantiomerically pure compounds has led to important advances in asymmetric catalysis, especially using chiral organometallic compounds. In this context the search of new catalysts is very important, mainly focusing on the properties of the chiral ligands. This has led to the...
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| Tipo de documento: | tese |
| Estado: | Versão publicada |
| Data de publicação: | 2013 |
| País: | España |
| Recursos: | Universitat Rovira i virgili (URV) |
| Repositório: | Repositori Institucional de la Universitat Rovira i Virgili |
| OAI Identifier: | oai:urv.cat:TDX:1319 |
| Acesso em linha: | https://hdl.handle.net/20.500.11797/TDX1319 http://hdl.handle.net/10803/129285 |
| Access Level: | Acceso aberto |
| Palavra-chave: | 546 - Química inorgànica 542 - Química pràctica de laboratori. Química preparativa i experimental 54 - Química |
| Resumo: | The growing demand for enantiomerically pure compounds has led to important advances in asymmetric catalysis, especially using chiral organometallic compounds. In this context the search of new catalysts is very important, mainly focusing on the properties of the chiral ligands. This has led to the development of new chiral ligands. An important source of chiral ligands is derivatives carbohydrate derivatives because of their high availability, their low cost and their high functionality. The objectives of this thesis are to develop two new chiral ligands carbohydrate derivatives. Specifically thioether-phosphite and furanoside monophosphite, for application in several important asymmetric catalytic reactions as Rh- and Ir-catalyzed hydrogenation of functionalized and unfunctionalized olefins, respectively; Pd-catalyzed allylic substitution; and Ni-catalyzed 1,2-addition of trialkylaluminum reagents to aldehydes. |
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