Clinical Usefulness of Anthropometric Indices to Predict the Presence of Prediabetes. Data from the ILERVAS Cohort

Prediabetes is closely related to excess body weight and adipose distribution. For this reason, we aimed to assess and compare the diagnostic usefulness of ten anthropometric adiposity indices to predict prediabetes. Cross-sectional study with 8188 overweight subjects free of type 2 diabetes from th...

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Authors: Sanchez, M, Sanchez, E, Bermudez-Lopez, M, Torres, G, Farras-Salles, C, Pamplona, R, Castro-Boque, E, Valdivielso, JM, Purroy, F, Martinez-Alonso, M, Godoy, P, Mauricio, D, Fernandez, E, Hernandez, M, Rius, F, Lecube, A
Format: article
Status:Published version
Publication Date:2021
Country:España
Institution:Institut d’Investigació Biomèdica Sant Pau (IIB Sant Pau)
Repository:r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
OAI Identifier:oai:iibsantpau.fundanetsuite.com:p4954
Online Access:https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=4954
https://ddd.uab.cat/record/272081
Access Level:Open access
Keyword:adiposity
body composition
prediabetes
glycated hemoglobin
obesity
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spelling Clinical Usefulness of Anthropometric Indices to Predict the Presence of Prediabetes. Data from the ILERVAS CohortSanchez, MSanchez, EBermudez-Lopez, MTorres, GFarras-Salles, CPamplona, RCastro-Boque, EValdivielso, JMPurroy, FMartinez-Alonso, MGodoy, PMauricio, DFernandez, EHernandez, MRius, FLecube, Aadipositybody compositionprediabetesglycated hemoglobinobesityPrediabetes is closely related to excess body weight and adipose distribution. For this reason, we aimed to assess and compare the diagnostic usefulness of ten anthropometric adiposity indices to predict prediabetes. Cross-sectional study with 8188 overweight subjects free of type 2 diabetes from the ILERVAS project (NCT03228459). Prediabetes was diagnosed by levels of glycated hemoglobin (HbA1c). Total body adiposity indices [BMI, Clinica Universidad de Navarra-Body Adiposity Estimator (CUN-BAE) and Deurenberg's formula] and abdominal adiposity (waist and neck circumferences, conicity index, waist to height ratio, Bonora's equation, A body shape index, and body roundness index) were calculated. The area under the receiver-operating characteristic (ROC) curve, the best cutoff and the prevalence of prediabetes around this value were calculated for every anthropometric index. All anthropometric indices other than the A body adiposity were higher in men and women with prediabetes compared with controls (p < 0.001 for all). In addition, a slightly positive correlation was found between indices and HbA1c in both sexes (r <= 0.182 and p <= 0.026 for all). None of the measures achieved acceptable levels of discrimination in ROC analysis (area under the ROC <= 0.63 for all). Assessing BMI, the prevalence of prediabetes among men increased from 20.4% to 36.2% around the cutoff of 28.2 kg/m(2), with similar data among women (from 29.3 to 44.8% with a cutoff of 28.6 kg/m(2)). No lonely obesity index appears to be the perfect biomarker to use in clinical practice to detect individuals with prediabetes.MDPI2021info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttps://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=4954https://ddd.uab.cat/record/272081NutrientsISSN: 20726643reponame:r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pauinstname:Institut d’Investigació Biomèdica Sant Pau (IIB Sant Pau)Inglésinfo:eu-repo/semantics/openAccessoai:iibsantpau.fundanetsuite.com:p49542026-06-14T12:41:47Z
dc.title.none.fl_str_mv Clinical Usefulness of Anthropometric Indices to Predict the Presence of Prediabetes. Data from the ILERVAS Cohort
title Clinical Usefulness of Anthropometric Indices to Predict the Presence of Prediabetes. Data from the ILERVAS Cohort
spellingShingle Clinical Usefulness of Anthropometric Indices to Predict the Presence of Prediabetes. Data from the ILERVAS Cohort
Sanchez, M
adiposity
body composition
prediabetes
glycated hemoglobin
obesity
title_short Clinical Usefulness of Anthropometric Indices to Predict the Presence of Prediabetes. Data from the ILERVAS Cohort
title_full Clinical Usefulness of Anthropometric Indices to Predict the Presence of Prediabetes. Data from the ILERVAS Cohort
title_fullStr Clinical Usefulness of Anthropometric Indices to Predict the Presence of Prediabetes. Data from the ILERVAS Cohort
title_full_unstemmed Clinical Usefulness of Anthropometric Indices to Predict the Presence of Prediabetes. Data from the ILERVAS Cohort
title_sort Clinical Usefulness of Anthropometric Indices to Predict the Presence of Prediabetes. Data from the ILERVAS Cohort
dc.creator.none.fl_str_mv Sanchez, M
Sanchez, E
Bermudez-Lopez, M
Torres, G
Farras-Salles, C
Pamplona, R
Castro-Boque, E
Valdivielso, JM
Purroy, F
Martinez-Alonso, M
Godoy, P
Mauricio, D
Fernandez, E
Hernandez, M
Rius, F
Lecube, A
author Sanchez, M
author_facet Sanchez, M
Sanchez, E
Bermudez-Lopez, M
Torres, G
Farras-Salles, C
Pamplona, R
Castro-Boque, E
Valdivielso, JM
Purroy, F
Martinez-Alonso, M
Godoy, P
Mauricio, D
Fernandez, E
Hernandez, M
Rius, F
Lecube, A
author_role author
author2 Sanchez, E
Bermudez-Lopez, M
Torres, G
Farras-Salles, C
Pamplona, R
Castro-Boque, E
Valdivielso, JM
Purroy, F
Martinez-Alonso, M
Godoy, P
Mauricio, D
Fernandez, E
Hernandez, M
Rius, F
Lecube, A
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv adiposity
body composition
prediabetes
glycated hemoglobin
obesity
topic adiposity
body composition
prediabetes
glycated hemoglobin
obesity
description Prediabetes is closely related to excess body weight and adipose distribution. For this reason, we aimed to assess and compare the diagnostic usefulness of ten anthropometric adiposity indices to predict prediabetes. Cross-sectional study with 8188 overweight subjects free of type 2 diabetes from the ILERVAS project (NCT03228459). Prediabetes was diagnosed by levels of glycated hemoglobin (HbA1c). Total body adiposity indices [BMI, Clinica Universidad de Navarra-Body Adiposity Estimator (CUN-BAE) and Deurenberg's formula] and abdominal adiposity (waist and neck circumferences, conicity index, waist to height ratio, Bonora's equation, A body shape index, and body roundness index) were calculated. The area under the receiver-operating characteristic (ROC) curve, the best cutoff and the prevalence of prediabetes around this value were calculated for every anthropometric index. All anthropometric indices other than the A body adiposity were higher in men and women with prediabetes compared with controls (p < 0.001 for all). In addition, a slightly positive correlation was found between indices and HbA1c in both sexes (r <= 0.182 and p <= 0.026 for all). None of the measures achieved acceptable levels of discrimination in ROC analysis (area under the ROC <= 0.63 for all). Assessing BMI, the prevalence of prediabetes among men increased from 20.4% to 36.2% around the cutoff of 28.2 kg/m(2), with similar data among women (from 29.3 to 44.8% with a cutoff of 28.6 kg/m(2)). No lonely obesity index appears to be the perfect biomarker to use in clinical practice to detect individuals with prediabetes.
publishDate 2021
dc.date.none.fl_str_mv 2021
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=4954
https://ddd.uab.cat/record/272081
url https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=4954
https://ddd.uab.cat/record/272081
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv Nutrients
ISSN: 20726643
reponame:r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname:Institut d’Investigació Biomèdica Sant Pau (IIB Sant Pau)
instname_str Institut d’Investigació Biomèdica Sant Pau (IIB Sant Pau)
reponame_str r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
collection r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,811543

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