Strontium Ions Substitution in Brushite Crystals: The Role of Strontium Chloride

The incorporation of strontium chloride to brushite cement was successful to introduce strontium ions within the lattice of brushite crystals. The effect of strontium ions on brushite cement properties was concentration dependent; such that, the addition of 5% and 10% (w/w) SrCl2 significantly incre...

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Detalles Bibliográficos
Autores: Alkhraisat, Mohammad H., Rueda, Carmen, López Cabarcos, Enrique
Tipo de recurso: artículo
Fecha de publicación:2011
País:España
Institución:Universidad Complutense de Madrid (UCM)
Repositorio:Docta Complutense
Idioma:inglés
OAI Identifier:oai:docta.ucm.es:20.500.14352/43282
Acceso en línea:https://hdl.handle.net/20.500.14352/43282
Access Level:acceso abierto
Palabra clave:Brushite
calcium phosphate cement
strontium
glycolic acid
Química farmaceútica
Química física (Farmacia)
2390 Química Farmacéutica
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spelling Strontium Ions Substitution in Brushite Crystals: The Role of Strontium ChlorideAlkhraisat, Mohammad H.Rueda, CarmenLópez Cabarcos, EnriqueBrushitecalcium phosphate cementstrontiumglycolic acidQuímica farmaceúticaQuímica física (Farmacia)2390 Química FarmacéuticaThe incorporation of strontium chloride to brushite cement was successful to introduce strontium ions within the lattice of brushite crystals. The effect of strontium ions on brushite cement properties was concentration dependent; such that, the addition of 5% and 10% (w/w) SrCl2 significantly increased the cement FST and the addition of 10% SrCl2 decreased the cement tensile strength. Further, cement weight loss was shown to be increased by cement modification with SrCl2. The combination of ionic substitution and the degradability of brushite cements would constitute a system for the local delivery of strontium ions in the treatment of osteoporosis.MDPIUniversidad Complutense de Madrid20112011-05-3120112011-05-31journal articlehttp://purl.org/coar/resource_type/c_6501info:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/20.500.14352/43282reponame:Docta Complutenseinstname:Universidad Complutense de Madrid (UCM)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2Atribución 3.0 Españahttps://creativecommons.org/licenses/by/3.0/es/info:eu-repo/semantics/openAccessoai:docta.ucm.es:20.500.14352/432822026-06-02T12:44:21Z
dc.title.none.fl_str_mv Strontium Ions Substitution in Brushite Crystals: The Role of Strontium Chloride
title Strontium Ions Substitution in Brushite Crystals: The Role of Strontium Chloride
spellingShingle Strontium Ions Substitution in Brushite Crystals: The Role of Strontium Chloride
Alkhraisat, Mohammad H.
Brushite
calcium phosphate cement
strontium
glycolic acid
Química farmaceútica
Química física (Farmacia)
2390 Química Farmacéutica
title_short Strontium Ions Substitution in Brushite Crystals: The Role of Strontium Chloride
title_full Strontium Ions Substitution in Brushite Crystals: The Role of Strontium Chloride
title_fullStr Strontium Ions Substitution in Brushite Crystals: The Role of Strontium Chloride
title_full_unstemmed Strontium Ions Substitution in Brushite Crystals: The Role of Strontium Chloride
title_sort Strontium Ions Substitution in Brushite Crystals: The Role of Strontium Chloride
dc.creator.none.fl_str_mv Alkhraisat, Mohammad H.
Rueda, Carmen
López Cabarcos, Enrique
author Alkhraisat, Mohammad H.
author_facet Alkhraisat, Mohammad H.
Rueda, Carmen
López Cabarcos, Enrique
author_role author
author2 Rueda, Carmen
López Cabarcos, Enrique
author2_role author
author
dc.contributor.none.fl_str_mv Universidad Complutense de Madrid
dc.subject.none.fl_str_mv Brushite
calcium phosphate cement
strontium
glycolic acid
Química farmaceútica
Química física (Farmacia)
2390 Química Farmacéutica
topic Brushite
calcium phosphate cement
strontium
glycolic acid
Química farmaceútica
Química física (Farmacia)
2390 Química Farmacéutica
description The incorporation of strontium chloride to brushite cement was successful to introduce strontium ions within the lattice of brushite crystals. The effect of strontium ions on brushite cement properties was concentration dependent; such that, the addition of 5% and 10% (w/w) SrCl2 significantly increased the cement FST and the addition of 10% SrCl2 decreased the cement tensile strength. Further, cement weight loss was shown to be increased by cement modification with SrCl2. The combination of ionic substitution and the degradability of brushite cements would constitute a system for the local delivery of strontium ions in the treatment of osteoporosis.
publishDate 2011
dc.date.none.fl_str_mv 2011
2011-05-31
2011
2011-05-31
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://hdl.handle.net/20.500.14352/43282
url https://hdl.handle.net/20.500.14352/43282
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Atribución 3.0 España
https://creativecommons.org/licenses/by/3.0/es/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Atribución 3.0 España
https://creativecommons.org/licenses/by/3.0/es/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:Docta Complutense
instname:Universidad Complutense de Madrid (UCM)
instname_str Universidad Complutense de Madrid (UCM)
reponame_str Docta Complutense
collection Docta Complutense
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869417464591286272
score 15,300719

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