A progesterone derivative linked to a stable phospholipid activates breast cancer cell response without leaving the cell membrane

Open Access funding provided thanks to the CRUE-CSIC agreement with Springer Nature. This work was supported in part by the Spanish Ministerio de Ciencia e Innovación (MCI), Agencia Estatal de Investigación (AEI) and Fondo Europeo de Desarrollo Regional (FEDER) (grant No. PGC2018-099857-B-I00), by t...

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Detalles Bibliográficos
Autores: Font-Mateu, Jofre, Sanllehí, Pol, Sot, Jesus, Abad, Beatriz, Mateos, Nicolas, Torreno-Pina, Juan Andres, Ferrari, Roberto, Wright, Roni, Garcia-Parajo, Maria F., Joglar, Jesús, Goñi, Félix M., Beato, Miguel
Tipo de recurso: artículo
Fecha de publicación:2024
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:20.500.12328/4179
Acceso en línea:http://hdl.handle.net/20.500.12328/4179
https://dx.doi.org/10.1007/s00018-024-05116-3
Access Level:acceso abierto
Palabra clave:Receptor de progesterona
Cèl·lules de càncer de mama
Senyalització de progesterona
Receptors d'hormones nuclears
Cèl·lula fosfolípids de membrana
Células de cáncer de mama
Señalización de progesterona
Receptores hormonales nucleares
Célula fosfolípidos de membrana
Progesterone receptor
Breast cancer cells
Progesterone signaling
Nuclear hormone receptors
Cell membrane phospholipids
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Sumario:Open Access funding provided thanks to the CRUE-CSIC agreement with Springer Nature. This work was supported in part by the Spanish Ministerio de Ciencia e Innovación (MCI), Agencia Estatal de Investigación (AEI) and Fondo Europeo de Desarrollo Regional (FEDER) (grant No. PGC2018-099857-B-I00), by the Basque Government (grants No. IT1625-22 and IT1270-19), by Fundación Ramón Areces (CIVP20A6619), by Fundación Biofísica Bizkaia, and by the Basque Excellence Research Centre (BERC) program of the Basque Government. This research was also supported by European Research Council (Project "4D Genome" 609989), the Ministerio de Economía y Competitividad (Project G62426937) and the Generalitat de Catalunya (Project AGAUR SGR 575 and AGAUR 2019PROD00115/IU68-016733), European Research Council -Proof Of Concept (Project “Impacct” 825176). This work has benefted from the equipment and framework of the COMP-HUB and COMP-R Initiatives, funded by the 'Departments of Excellence' Program of the Italian Ministry for University and Research (MIUR, 2018–2022 and MUR, 2022–2027).