Genomics-led approach to drug testing in models of undifferentiated pleomorphic sarcoma

[Data accessibility] The genomic data generated for patient tumours, cell lines and PDX models presented in this manuscript are currently under upload to the European Genome-Phenome Archive (EGA: https://ega-archive.org/) and will be available upon reasonable request. The WGS reads from UPS samples...

Descripción completa

Detalles Bibliográficos
Autores: Manasterski, Piotr, Danks, Molly R., Thomson, John P., Muir, Morwenna, Lee, Martin, Dawson, John C., Amaral, Ana Teresa, Diaz-Martin, Juan, Moura, David S., Martín-Broto, Javier, Alsaadi, Ali, Salter, Donald M., Oswald, Ailsa J., Grimes, Graeme R., Hayward, Larry, Hupp, Ted, Sisley, Karen, Huang, Paul H., Carragher, Neil O., Brunton, Valerie G.
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2025
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/412141
Acceso en línea:http://hdl.handle.net/10261/412141
https://api.elsevier.com/content/abstract/scopus_id/105006831780
Access Level:acceso abierto
Palabra clave:Drug screening
Patient‐derived xenograft
Tumour slices
Undifferentiated pleomorphic sarcoma
Whole exome sequencing
Descripción
Sumario:[Data accessibility] The genomic data generated for patient tumours, cell lines and PDX models presented in this manuscript are currently under upload to the European Genome-Phenome Archive (EGA: https://ega-archive.org/) and will be available upon reasonable request. The WGS reads from UPS samples sequenced in the TCGA Sarcoma project were downloaded in aligned BAM format from the National Cancer Institute Protected Data Cloud Portal (https://portal.gdc.cancer.gov/).

Similares en LA Referencia