DBP rs7041 and DHCR7 rs3829251 are Linked to CD4+ Recovery in HIV Patients on Antiretroviral Therapy

[Background] The lack of the recovery of CD4+ T-cells (CD4+ recovery) among immunodeficiency virus (HIV)-infected patients on antiretroviral therapy (ART) is not well known. We aimed to analyze the association between single nucleotide polymorphisms (SNPs) underlying vitamin D metabolism and the CD4...

ver descrição completa

Detalhes bibliográficos
Autores: Resino, Salvador, Jiménez-Sousa, María A., Blanco, Julià, Pacheco, Yolanda M., Romero, Jorge del, Peraire, Joaquim, Virseda-Berdices, Ana, Muñoz-Gómez, María José, Galera-Peñaranda, Carlos, García-Fraile, Lucio Jesús, Benito, José Miguel, Rallón, Norma
Tipo de documento: artigo
Estado:Versão publicada
Data de publicação:2021
País:España
Recursos:Consejo Superior de Investigaciones Científicas (CSIC)
Repositório:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/269455
Acesso em linha:http://hdl.handle.net/10261/269455
Access Level:Acceso aberto
Palavra-chave:HIV
Antiretroviral therapy
DHCR7
DBP
SNP
Immune reconstitution
CD4+ T cells
Descrição
Resumo:[Background] The lack of the recovery of CD4+ T-cells (CD4+ recovery) among immunodeficiency virus (HIV)-infected patients on antiretroviral therapy (ART) is not well known. We aimed to analyze the association between single nucleotide polymorphisms (SNPs) underlying vitamin D metabolism and the CD4+ recovery in naïve HIV-infected patients who started ART with low baseline CD4+.

Registros relacionados