Pancreatic Organoids for Regenerative Medicine and Cancer Research

In recent years, the development of ex vivo organoid cultures has gained substantial attention as a model to study regenerative medicine and diseases in several tissues. Diabetes and pancreatic ductal adenocarcinoma (PDAC) are the two major devastating diseases affecting the pancreas. Suitable model...

Descripción completa

Detalles Bibliográficos
Autores: Casamitjana, Joan, Espinet, Elisa, Rovira, Meritxell
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2022
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/186150
Acceso en línea:https://hdl.handle.net/2445/186150
Access Level:acceso abierto
Palabra clave:Malalties del pàncrees
Medicina regenerativa
Pancréas diseases
Regenerative medicine
id ES_b647849ced6da613452ec059be21f57a
oai_identifier_str oai:recercat.cat:2445/186150
network_acronym_str ES
network_name_str España
repository_id_str
spelling Pancreatic Organoids for Regenerative Medicine and Cancer ResearchCasamitjana, JoanEspinet, ElisaRovira, MeritxellMalalties del pàncreesMedicina regenerativaPancréas diseasesRegenerative medicineIn recent years, the development of ex vivo organoid cultures has gained substantial attention as a model to study regenerative medicine and diseases in several tissues. Diabetes and pancreatic ductal adenocarcinoma (PDAC) are the two major devastating diseases affecting the pancreas. Suitable models for regenerative medicine in diabetes and to accurately study PDAC biology and treatment response are essential in the pancreatic field. Pancreatic organoids can be generated from healthy pancreas or pancreatic tumors and constitute an important translational bridge between in vitro and in vivo models. Here, we review the rapidly emerging field of pancreatic organoids and summarize the current applications of the technology to tissue regeneration, disease modelling, and drug screening.Frontiers Media2022202220222022info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion13 p.application/pdfapplication/pdfhttps://hdl.handle.net/2445/186150Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))reponame:Recercat. Dipósit de la Recerca de Catalunyainstname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)InglésReproducció del document publicat a: https://doi.org/10.3389/fcell.2022.886153Frontiers in Cell and Developmental Biology, 2022, vol. 10https://doi.org/10.3389/fcell.2022.886153cc by (c) Casamitjana, Joan et al, 2022http://creativecommons.org/licenses/by/3.0/es/info:eu-repo/semantics/openAccessoai:recercat.cat:2445/1861502026-05-29T05:05:01Z
dc.title.none.fl_str_mv Pancreatic Organoids for Regenerative Medicine and Cancer Research
title Pancreatic Organoids for Regenerative Medicine and Cancer Research
spellingShingle Pancreatic Organoids for Regenerative Medicine and Cancer Research
Casamitjana, Joan
Malalties del pàncrees
Medicina regenerativa
Pancréas diseases
Regenerative medicine
title_short Pancreatic Organoids for Regenerative Medicine and Cancer Research
title_full Pancreatic Organoids for Regenerative Medicine and Cancer Research
title_fullStr Pancreatic Organoids for Regenerative Medicine and Cancer Research
title_full_unstemmed Pancreatic Organoids for Regenerative Medicine and Cancer Research
title_sort Pancreatic Organoids for Regenerative Medicine and Cancer Research
dc.creator.none.fl_str_mv Casamitjana, Joan
Espinet, Elisa
Rovira, Meritxell
author Casamitjana, Joan
author_facet Casamitjana, Joan
Espinet, Elisa
Rovira, Meritxell
author_role author
author2 Espinet, Elisa
Rovira, Meritxell
author2_role author
author
dc.subject.none.fl_str_mv Malalties del pàncrees
Medicina regenerativa
Pancréas diseases
Regenerative medicine
topic Malalties del pàncrees
Medicina regenerativa
Pancréas diseases
Regenerative medicine
description In recent years, the development of ex vivo organoid cultures has gained substantial attention as a model to study regenerative medicine and diseases in several tissues. Diabetes and pancreatic ductal adenocarcinoma (PDAC) are the two major devastating diseases affecting the pancreas. Suitable models for regenerative medicine in diabetes and to accurately study PDAC biology and treatment response are essential in the pancreatic field. Pancreatic organoids can be generated from healthy pancreas or pancreatic tumors and constitute an important translational bridge between in vitro and in vivo models. Here, we review the rapidly emerging field of pancreatic organoids and summarize the current applications of the technology to tissue regeneration, disease modelling, and drug screening.
publishDate 2022
dc.date.none.fl_str_mv 2022
2022
2022
2022
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/186150
url https://hdl.handle.net/2445/186150
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Reproducció del document publicat a: https://doi.org/10.3389/fcell.2022.886153
Frontiers in Cell and Developmental Biology, 2022, vol. 10
https://doi.org/10.3389/fcell.2022.886153
dc.rights.none.fl_str_mv cc by (c) Casamitjana, Joan et al, 2022
http://creativecommons.org/licenses/by/3.0/es/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv cc by (c) Casamitjana, Joan et al, 2022
http://creativecommons.org/licenses/by/3.0/es/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 13 p.
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Frontiers Media
publisher.none.fl_str_mv Frontiers Media
dc.source.none.fl_str_mv Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))
reponame:Recercat. Dipósit de la Recerca de Catalunya
instname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
instname_str Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
reponame_str Recercat. Dipósit de la Recerca de Catalunya
collection Recercat. Dipósit de la Recerca de Catalunya
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869417433647808512
score 15,81155

Similares en LA Referencia