Theoretical Aspects of Thioamides

Quantum chemical calculations can afford valuable information to understand the chemical processes and the structural features of chemical species. This tool has become very informative, and several aspects can be discussed on the thioamides under a theoretical point of view such as the effects of s...

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Detalles Bibliográficos
Autores: Cuevas Vicario, José Vicente, García Calvo, José, García Calvo, Víctor, García Herbosa, Gabriel, Torroba Pérez, Tomás
Tipo de recurso: capítulo de libro
Estado:Versión aceptada para publicación
Fecha de publicación:2019
País:España
Institución:Universidad de Burgos (UBU)
Repositorio:Repositorio Institucional de la Universidad de Burgos (RIUBU)
OAI Identifier:oai:riubu.ubu.es:10259/8381
Acceso en línea:http://hdl.handle.net/10259/8381
Access Level:acceso abierto
Palabra clave:Thioamides
Quantum chemistry
DFT
HF
Química inorgánica
Chemistry, Inorganic
Descripción
Sumario:Quantum chemical calculations can afford valuable information to understand the chemical processes and the structural features of chemical species. This tool has become very informative, and several aspects can be discussed on the thioamides under a theoretical point of view such as the effects of structure in their planarity and some cases with derivations of that planarity, C–N bond rotation in comparison to the related amides and selenoamides and implications in the transition state, and the influence of the solvent or the influence of remote substituents. This review will deal as well with isomerization processes such as tautomerization or rotation of N-bonded methyl groups. Some aspects of reactivity of thioamides such as the bonddissociation enthalpy (BDE) or their behavior as radical scavengers are discussed as well. Some comments on the theoretical aspects of thiopeptides are briefly analyzed.