Recommendations of the Spanish Working Group on Crohn's Disease and Ulcerative Colitis (GETECCU) on topical therapy in ulcerative colitis

Although most patients with ulcerative colitis should be given topical treatment, different studies have shown that they are underused in clinical practice. The purpose of this article is to answer 10 specific questions about which drugs are available for topical use in the treatment of ulcerative c...

ver descrição completa

Detalhes bibliográficos
Autores: Ginard, D, Marin-Jimenez, I, Barreiro-de Acosta, M, Ricart, E, Domenech, E, Gisbert, JP, Esteve, M, Representacion GETECCU, Minguez, M
Tipo de documento: artigo
Estado:Versão publicada
Data de publicação:2020
País:España
Recursos:INCLIVA
Repositório:r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
OAI Identifier:oai:incliva.fundanetsuite.com:p4410
Acesso em linha:https://incliva.portalinvestigacion.com/publicaciones/4410
Access Level:Acceso aberto
Palavra-chave:Topical treatment
Ulcerative colitis
Mesalazine
Corticosteroids
Descrição
Resumo:Although most patients with ulcerative colitis should be given topical treatment, different studies have shown that they are underused in clinical practice. The purpose of this article is to answer 10 specific questions about which drugs are available for topical use in the treatment of ulcerative colitis, and their characteristics in terms of formulation, dosage, presentation, application and proximal distribution of rectal-administered drugs. The efficacy of available topical drugs and the benefits of combining different formulations and routes of administration, and their usefulness during disease remission are evaluated. Finally, a series of recommendations addressed to patients are given on the correct application of topical treatment. (C) 2019 The Authors. Published by Elsevier Espana, S.L.U.