Magnetic reduced graphene oxide/nickel/platinum nanoparticles micromotors for mycotoxin analysis

Magnetic reduced graphene oxide/nickel/platinum nanoparticles (rGO/Ni/PtNPs) micromotors for mycotoxin analysis in food samples were developed for food-safety diagnosis. While the utilization of self-propelled micromotors in bioassays has led to a fundamentally new approach, mainly due to the greatl...

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Detalles Bibliográficos
Autores: Escarpa Miguel, Jesús Alberto|||0000-0002-7302-0948, López Gil, Miguel Ángel|||0000-0003-3711-010X, Molinero Fernández, Águeda, Moreno Guzmán, María
Tipo de recurso: artículo
Fecha de publicación:2018
País:España
Institución:Universidad de Alcalá (UAH)
Repositorio:e_Buah Biblioteca Digital Universidad de Alcalá
Idioma:inglés
OAI Identifier:oai:ebuah.uah.es:10017/60471
Acceso en línea:http://hdl.handle.net/10017/60471
https://dx.doi.org/10.1002/ chem.201706095
Access Level:acceso abierto
Palabra clave:adsorption
analytical methods
electrochemistry
micromotors
mycotoxins
Química
Chemistry
Descripción
Sumario:Magnetic reduced graphene oxide/nickel/platinum nanoparticles (rGO/Ni/PtNPs) micromotors for mycotoxin analysis in food samples were developed for food-safety diagnosis. While the utilization of self-propelled micromotors in bioassays has led to a fundamentally new approach, mainly due to the greatly enhanced target?receptor contacts owing to their continuous movement around the sample and the associated mixing effect, herein the magnetic properties of rGO/Ni/PtNPs micromotors for mycotoxin analysis are additionally explored. The micromotor-based strategy for targeted mycotoxin biosensing focused on the accurate control of micromotor-based operations: 1) on-the-move capture of free aptamers by exploiting the adsorption (outer rGO layer) and catalytic (inner PtNPs layer) properties and 2) micromotor stopped flow in just 2 min by exploiting the magnetic properties (intermediate Ni layer). This strategy allowed fumonisin B1 determination with high sensitivity (limit of detection: 0.70 ngmL@1) and excellent accuracy (error: 0.05% in certified reference material and quantitative recoveries of 104:4% in beer) even in the presence of concurrent ochratoxin A (105?108:8% in wines). These results confirm the developed approach as an innovative and reliable analytical tool for food-safety monitoring, and confirm the role of micromotors as a new paradigm in analytical chemistry.