Physical analysis of a processive molecular motor: the conventional kinesin

We present a model that allows for the derivation of the experimentally accesible observables: spatial steps, mean velocity, stall force, useful power, efficiency and randomness, etc. as a function of the adenosine triphosphate concentration and an external load F. The model presents a minimum of ad...

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Detalles Bibliográficos
Autores: Alva, Aleix|||0000-0001-7966-371X, Lacasta Palacio, Ana María|||0000-0002-9060-6043, Sancho, Jose Maria
Tipo de recurso: artículo
Fecha de publicación:2005
País:España
Institución:Universitat Politècnica de Catalunya (UPC)
Repositorio:UPCommons. Portal del coneixement obert de la UPC
Idioma:inglés
OAI Identifier:oai:upcommons.upc.edu:2117/2503
Acceso en línea:https://hdl.handle.net/2117/2503
https://dx.doi.org/10.1103/PhysRevE.72.031918
Access Level:acceso abierto
Palabra clave:Biophysics
Molecular biology
Molecular motors
Kinesin
Biofísica
Descripción
Sumario:We present a model that allows for the derivation of the experimentally accesible observables: spatial steps, mean velocity, stall force, useful power, efficiency and randomness, etc. as a function of the adenosine triphosphate concentration and an external load F. The model presents a minimum of adjustable parameters and the theoretical predictions compare well with the available experimental results.