Plasmin Generation Potential and Recanalization in Acute Ischaemic Stroke; an Observational Cohort Study of Stroke Biobank Samples

[Rationale] More than half of patients who receive thrombolysis for acute ischaemic stroke fail to recanalize. Elucidating biological factors which predict recanalization could identify therapeutic targets for increasing thrombolysis success.

Detalles Bibliográficos
Autores: Lillicrap, Thomas, Keragala, Charithani B., Draxler, Dominik F., Chan, Jilly, Ho, Heidi, Harman, Stevi, Niego, Be'eri, Holliday, Elizabeth, Levi, Christopher R., García-Esperon, Carlos, Spratt, Neil, Gyawali, Prajwal, Bivard, Andrew, Parsons, Michael W., Montaner, Joan, Bustamante, Alejandro, Fernández-Cadenas, Israel, Cloud, Geoffrey, Maguire, Jane, Lincz, Lisa, Kleinig, Timothy, Attia, John, Koblar, Simon, Hamilton-Bruce, Monica Anne, Choi, Philip, Worrall, Bradford B., Medcalf, Robert L.
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2020
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/236523
Acceso en línea:http://hdl.handle.net/10261/236523
Access Level:acceso abierto
Palabra clave:Acute stroke therapy
Fibrinolysis
rtPA
Thrombolysis
Plasmin
Stroke
Recanalization
Descripción
Sumario:[Rationale] More than half of patients who receive thrombolysis for acute ischaemic stroke fail to recanalize. Elucidating biological factors which predict recanalization could identify therapeutic targets for increasing thrombolysis success.

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