Evaluation of the validated intraoperative bleeding scale in liver surgery: study protocol for a multicenter prospective study

Background: Surgical hemostasis has become one of the key principles in the advancement of surgery. Hemostatic agents are commonly administered in many surgical specialties, although the lack of consensus on the definition of intraoperative bleeding or of a standardized system for its classification...

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Autores: Aparicio-López, D, Asencio-Pascual, JM, Blanco-Fernández, G, Cugat-Andorrá, E, Gómez-Bravo, MA, López-Ben, S, Martín-Pérez, E, Sabater, L, Ramia, JM, Serradilla-Martín, M
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2023
País:España
Institución:INCLIVA
Repositorio:r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
OAI Identifier:oai:incliva.fundanetsuite.com:p17925
Acceso en línea:https://incliva.portalinvestigacion.com/publicaciones/17925
Access Level:acceso abierto
Palabra clave:liver surgery
predictive score
intraoperative bleeding
surgical hemostasis
hemostatic agent
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spelling Evaluation of the validated intraoperative bleeding scale in liver surgery: study protocol for a multicenter prospective studyAparicio-López, DAsencio-Pascual, JMBlanco-Fernández, GCugat-Andorrá, EGómez-Bravo, MALópez-Ben, SMartín-Pérez, ESabater, LRamia, JMSerradilla-Martín, Mliver surgerypredictive scoreintraoperative bleedingsurgical hemostasishemostatic agentBackground: Surgical hemostasis has become one of the key principles in the advancement of surgery. Hemostatic agents are commonly administered in many surgical specialties, although the lack of consensus on the definition of intraoperative bleeding or of a standardized system for its classification means that often the most suitable agent is not selected. The recommendations of international organizations highlight the need for a bleeding severity scale, validated in clinical studies, that would allow the selection of the best hemostatic agent in each case. The primary objective of this study is to evaluate the VIBe scale (Validated Intraoperative Bleeding Scale) in humans. Secondary objectives are to evaluate the scale's usefulness in liver surgery; to determine the relationship between the extent of bleeding and the hemostatic agent used; and to assess the relationship between the grade of bleeding and postoperative complications.Methods: Prospective multicenter observational study including 259 liver resections that meet the inclusion criteria: patients scheduled for liver surgery at one of 10 medium-high volume Spanish HPB centers using an open or minimally invasive approach (robotic/laparoscopic/hybrid), regardless of diagnosis, ASA score <4, age >= 18, and who provide signed informed consent during the study period (September 2023 until the required sample size has been recruited). The participating researchers will be responsible for collecting the data and for reporting them to the study coordinators.Discussion: This study will allow us to evaluate the VIBe scale for intraoperative bleeding in humans, with a view to its subsequent incorporation in daily clinical practice.FRONTIERS MEDIA SA2023info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttps://incliva.portalinvestigacion.com/publicaciones/17925Frontiers in SurgeryISSN: 2296875Xreponame:r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVAinstname:INCLIVAInglésinfo:eu-repo/semantics/openAccessoai:incliva.fundanetsuite.com:p179252026-06-07T16:35:31Z
dc.title.none.fl_str_mv Evaluation of the validated intraoperative bleeding scale in liver surgery: study protocol for a multicenter prospective study
title Evaluation of the validated intraoperative bleeding scale in liver surgery: study protocol for a multicenter prospective study
spellingShingle Evaluation of the validated intraoperative bleeding scale in liver surgery: study protocol for a multicenter prospective study
Aparicio-López, D
liver surgery
predictive score
intraoperative bleeding
surgical hemostasis
hemostatic agent
title_short Evaluation of the validated intraoperative bleeding scale in liver surgery: study protocol for a multicenter prospective study
title_full Evaluation of the validated intraoperative bleeding scale in liver surgery: study protocol for a multicenter prospective study
title_fullStr Evaluation of the validated intraoperative bleeding scale in liver surgery: study protocol for a multicenter prospective study
title_full_unstemmed Evaluation of the validated intraoperative bleeding scale in liver surgery: study protocol for a multicenter prospective study
title_sort Evaluation of the validated intraoperative bleeding scale in liver surgery: study protocol for a multicenter prospective study
dc.creator.none.fl_str_mv Aparicio-López, D
Asencio-Pascual, JM
Blanco-Fernández, G
Cugat-Andorrá, E
Gómez-Bravo, MA
López-Ben, S
Martín-Pérez, E
Sabater, L
Ramia, JM
Serradilla-Martín, M
author Aparicio-López, D
author_facet Aparicio-López, D
Asencio-Pascual, JM
Blanco-Fernández, G
Cugat-Andorrá, E
Gómez-Bravo, MA
López-Ben, S
Martín-Pérez, E
Sabater, L
Ramia, JM
Serradilla-Martín, M
author_role author
author2 Asencio-Pascual, JM
Blanco-Fernández, G
Cugat-Andorrá, E
Gómez-Bravo, MA
López-Ben, S
Martín-Pérez, E
Sabater, L
Ramia, JM
Serradilla-Martín, M
author2_role author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv liver surgery
predictive score
intraoperative bleeding
surgical hemostasis
hemostatic agent
topic liver surgery
predictive score
intraoperative bleeding
surgical hemostasis
hemostatic agent
description Background: Surgical hemostasis has become one of the key principles in the advancement of surgery. Hemostatic agents are commonly administered in many surgical specialties, although the lack of consensus on the definition of intraoperative bleeding or of a standardized system for its classification means that often the most suitable agent is not selected. The recommendations of international organizations highlight the need for a bleeding severity scale, validated in clinical studies, that would allow the selection of the best hemostatic agent in each case. The primary objective of this study is to evaluate the VIBe scale (Validated Intraoperative Bleeding Scale) in humans. Secondary objectives are to evaluate the scale's usefulness in liver surgery; to determine the relationship between the extent of bleeding and the hemostatic agent used; and to assess the relationship between the grade of bleeding and postoperative complications.Methods: Prospective multicenter observational study including 259 liver resections that meet the inclusion criteria: patients scheduled for liver surgery at one of 10 medium-high volume Spanish HPB centers using an open or minimally invasive approach (robotic/laparoscopic/hybrid), regardless of diagnosis, ASA score <4, age >= 18, and who provide signed informed consent during the study period (September 2023 until the required sample size has been recruited). The participating researchers will be responsible for collecting the data and for reporting them to the study coordinators.Discussion: This study will allow us to evaluate the VIBe scale for intraoperative bleeding in humans, with a view to its subsequent incorporation in daily clinical practice.
publishDate 2023
dc.date.none.fl_str_mv 2023
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://incliva.portalinvestigacion.com/publicaciones/17925
url https://incliva.portalinvestigacion.com/publicaciones/17925
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv FRONTIERS MEDIA SA
publisher.none.fl_str_mv FRONTIERS MEDIA SA
dc.source.none.fl_str_mv Frontiers in Surgery
ISSN: 2296875X
reponame:r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
instname:INCLIVA
instname_str INCLIVA
reponame_str r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
collection r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
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