Data for Disposable electrochemical aptasensor for rapid and selective vancomycin detection in clinical samples: Bridging affinity selection, computational modeling and clinical validation

Complete description of the obtention of new aptamers against the antibiotic Vancomycin by using Magnetic-bead SELEX, their characterization by SPR, generation of the tridimensional structure for molecular docking and the development of adisposable electrochemical aptasensor for cost-effective and r...

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Detalles Bibliográficos
Autores: Casian, Magdolna, Hosu-Stancioiu, Oana, Manea, Ioana, Suárez Rodríguez, Dimas|||0000-0001-8003-2309, Díaz Fernández, Natalia|||0000-0002-9641-7630, Lobo Castañón, María Jesús|||0000-0002-2964-9490, Santos Álvarez, Noemí de los|||0000-0002-5216-6825, Cristea, Cecilia
Tipo de recurso: conjunto de datos
Fecha de publicación:2025
País:España
Institución:Universidad Pontificia de Salamanca
Repositorio:RUO. Repositorio Institucional de la Universidad de Oviedo
Idioma:inglés
OAI Identifier:oai:digibuo.uniovi.es:10651/80707
Acceso en línea:https://hdl.handle.net/10651/80707
https://dx.doi.org/10.17811/ruo_datasets.80707
Access Level:acceso abierto
Palabra clave:aptamer
Magnetic-bead SELEX
vancomycin
APTAMD software
molecular docking
electrochemical aptasensor
clinical serum monitoring
Descripción
Sumario:Complete description of the obtention of new aptamers against the antibiotic Vancomycin by using Magnetic-bead SELEX, their characterization by SPR, generation of the tridimensional structure for molecular docking and the development of adisposable electrochemical aptasensor for cost-effective and rapid monitoring of Vancomycin in serum. Validation with clinical samples from hospitalized patient under antibiotic treatment and comparsion with results obtained in the clinical laboratory.

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