Type 1 diabetic subjects with diabetic retinopathy show an unfavorable pattern of fat intake

Medical nutrition therapy is an important part of the management of type 1 diabetes mellitus (T1DM). Proper adherence to a healthy diet may have a favorable impact on diabetes management and its diabetic complications. Our aim was to assess differences in food and nutrient intake of type 1 diabetic...

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Detalles Bibliográficos
Autores: Granado Casas, Minerva, Ramírez-Morros, Anna, Martín, Mariona, Real, Jordi, Alonso, Núria, Valldeperas, Xavier, Traveset Maeso, Alicia, Rubinat, Esther, Alcubierre Calvo, Núria, Hernández García, Marta, Puig-Domingo, Manuel, Lecube Torelló, Albert, Castelblanco Echavarría, Esmeralda, Mauricio Puente, Dídac
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2018
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:10459.1/64754
Acceso en línea:https://doi.org/10.3390/nu10091184
http://hdl.handle.net/10459.1/64754
Access Level:acceso abierto
Palabra clave:Diabetis
Retinopatia diabètica
Àcids grassos
Àcid oleic
Diabetes
Diabetic retinopathy
Fatty acids
Oleic acid
Descripción
Sumario:Medical nutrition therapy is an important part of the management of type 1 diabetes mellitus (T1DM). Proper adherence to a healthy diet may have a favorable impact on diabetes management and its diabetic complications. Our aim was to assess differences in food and nutrient intake of type 1 diabetic patients with and without diabetic retinopathy (DR). This was a two-center, cross-sectional study in patients with T1DM, with and without DR. Subjects were recruited from the outpatient clinic of the two participating centers. A validated food frequency questionnaire was administered. A total of 103 T1DM patients with DR and 140 T1DM patient without DR were recruited. Subjects with DR showed a lower intake of total fat (p = 0.036) than that of their non-DR counterparts. DR was associated with increasing age (p = 0.004), hypertension (p < 0.001), and diabetes duration (p < 0.001), however there was a negative association with high educational level (p = 0.018). The multivariate-adjusted analysis showed that the intake of complex carbohydrates was positively related to the presence of DR (p = 0.031). In contrast, the intakes of total fat (p = 0.009), monounsaturated fatty acids (MUFAs) (p = 0.012), oleic acid (p = 0.012), and vitamin E (p = 0.006) were associated with the absence of DR. As conclusions, the intake of total MUFAs, oleic acid, and vitamin E is associated with a lower frequency of DR in patients with T1DM. These results suggest a potential protective effect of these lipid components for DR.