Maternal occupation during pregnancy, birth weight, and length of gestation: combined analysis of 13 European birth cohorts

Objectives. We assessed whether maternal employment during pregnancy – overall and in selected occupational sectors – is associated with birth weight, small for gestational age (SGA), term low birth weight (LBW), length of gestation, and preterm delivery in a population-based birth cohort design. Me...

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Autores: Casas Sanahuja, Maribel, Martínez, David, Kogevinas, Manolis, García, Ana María, Nieuwenhuijsen, Mark J., Vrijheid, Martine
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2015
País:España
Institución:Universitat Pompeu Fabra
Repositorio:Repositorio Digital de la UPF
OAI Identifier:oai:repositori.upf.edu:10230/58349
Acceso en línea:http://hdl.handle.net/10230/58349
http://dx.doi.org/10.5271/sjweh.3500
Access Level:acceso abierto
Palabra clave:Birth cohort
Birth weight
Cohort study
Europe
European birth cohort
Length of gestation
Low birth weight
Maternal occupation
Meta-analysis
Pregnancy
Preterm delivery
Small for gestational age
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spelling Maternal occupation during pregnancy, birth weight, and length of gestation: combined analysis of 13 European birth cohortsCasas Sanahuja, MaribelMartínez, DavidKogevinas, ManolisGarcía, Ana MaríaNieuwenhuijsen, Mark J.Vrijheid, MartineBirth cohortBirth weightCohort studyEuropeEuropean birth cohortLength of gestationLow birth weightMaternal occupationMeta-analysisPregnancyPreterm deliverySmall for gestational ageObjectives. We assessed whether maternal employment during pregnancy – overall and in selected occupational sectors – is associated with birth weight, small for gestational age (SGA), term low birth weight (LBW), length of gestation, and preterm delivery in a population-based birth cohort design. Methods. We used data from >200 000 mother-child pairs enrolled in 13 European birth cohorts and compared employed versus non-employed women. Among employees, we defined groups of occupations representing the main sectors of employment for women where potential reproductive hazards are considered to be present. The comparison group comprised all other employed women not included in the occupational sector being assessed. We performed meta-analyses of cohort-specific estimates and explored heterogeneity. Results. Employees had a lower risk of preterm delivery than non-employees [adjusted odds ratio (ORadj) 0.86, 95% confidence interval (95% CI) 0.81–0.91]. Working in most of the occupational sectors studied was not associated with adverse birth outcomes. Being employed as a nurse was associated with lower risk SGA infants (ORadj 0.91, 95% CI 0.84–0.99) whereas food industry workers had an increased risk of preterm delivery (ORadj 1.50, 95% CI 1.12–2.02). There was little evidence for heterogeneity between cohorts. Conclusions. This study suggests that, overall, employment during pregnancy is associated with a reduction in the risk of preterm birth and that work in certain occupations may affect pregnancy outcomes. This exploratory study provides an important platform on which to base further prospective studies focused on the potential consequences of maternal occupational exposures during pregnancy on child development.The authors would particularly like to thank all the cohort participants for their collaboration. The authors declare no conflicts of interest. This work has received funding from the European Union’s Seventh Framework Programme under grant agreement CHICOS nº 241604 and ENRIECO nº226285.NOROSH202320232015info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttp://hdl.handle.net/10230/58349http://dx.doi.org/10.5271/sjweh.3500reponame:Repositorio Digital de la UPFinstname:Universitat Pompeu FabraInglésScandinavian Journal of Work, Environment & Health. 2015 Jul;41(4):384-96info:eu-repo/grantAgreement/EC/FP7/241604info:eu-repo/grantAgreement/EC/FP7/226285This work is licensed under a Creative Commons Attribution 4.0 International License.http://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:repositori.upf.edu:10230/583492026-06-12T07:21:37Z
dc.title.none.fl_str_mv Maternal occupation during pregnancy, birth weight, and length of gestation: combined analysis of 13 European birth cohorts
title Maternal occupation during pregnancy, birth weight, and length of gestation: combined analysis of 13 European birth cohorts
spellingShingle Maternal occupation during pregnancy, birth weight, and length of gestation: combined analysis of 13 European birth cohorts
Casas Sanahuja, Maribel
Birth cohort
Birth weight
Cohort study
Europe
European birth cohort
Length of gestation
Low birth weight
Maternal occupation
Meta-analysis
Pregnancy
Preterm delivery
Small for gestational age
title_short Maternal occupation during pregnancy, birth weight, and length of gestation: combined analysis of 13 European birth cohorts
title_full Maternal occupation during pregnancy, birth weight, and length of gestation: combined analysis of 13 European birth cohorts
title_fullStr Maternal occupation during pregnancy, birth weight, and length of gestation: combined analysis of 13 European birth cohorts
title_full_unstemmed Maternal occupation during pregnancy, birth weight, and length of gestation: combined analysis of 13 European birth cohorts
title_sort Maternal occupation during pregnancy, birth weight, and length of gestation: combined analysis of 13 European birth cohorts
dc.creator.none.fl_str_mv Casas Sanahuja, Maribel
Martínez, David
Kogevinas, Manolis
García, Ana María
Nieuwenhuijsen, Mark J.
Vrijheid, Martine
author Casas Sanahuja, Maribel
author_facet Casas Sanahuja, Maribel
Martínez, David
Kogevinas, Manolis
García, Ana María
Nieuwenhuijsen, Mark J.
Vrijheid, Martine
author_role author
author2 Martínez, David
Kogevinas, Manolis
García, Ana María
Nieuwenhuijsen, Mark J.
Vrijheid, Martine
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv Birth cohort
Birth weight
Cohort study
Europe
European birth cohort
Length of gestation
Low birth weight
Maternal occupation
Meta-analysis
Pregnancy
Preterm delivery
Small for gestational age
topic Birth cohort
Birth weight
Cohort study
Europe
European birth cohort
Length of gestation
Low birth weight
Maternal occupation
Meta-analysis
Pregnancy
Preterm delivery
Small for gestational age
description Objectives. We assessed whether maternal employment during pregnancy – overall and in selected occupational sectors – is associated with birth weight, small for gestational age (SGA), term low birth weight (LBW), length of gestation, and preterm delivery in a population-based birth cohort design. Methods. We used data from >200 000 mother-child pairs enrolled in 13 European birth cohorts and compared employed versus non-employed women. Among employees, we defined groups of occupations representing the main sectors of employment for women where potential reproductive hazards are considered to be present. The comparison group comprised all other employed women not included in the occupational sector being assessed. We performed meta-analyses of cohort-specific estimates and explored heterogeneity. Results. Employees had a lower risk of preterm delivery than non-employees [adjusted odds ratio (ORadj) 0.86, 95% confidence interval (95% CI) 0.81–0.91]. Working in most of the occupational sectors studied was not associated with adverse birth outcomes. Being employed as a nurse was associated with lower risk SGA infants (ORadj 0.91, 95% CI 0.84–0.99) whereas food industry workers had an increased risk of preterm delivery (ORadj 1.50, 95% CI 1.12–2.02). There was little evidence for heterogeneity between cohorts. Conclusions. This study suggests that, overall, employment during pregnancy is associated with a reduction in the risk of preterm birth and that work in certain occupations may affect pregnancy outcomes. This exploratory study provides an important platform on which to base further prospective studies focused on the potential consequences of maternal occupational exposures during pregnancy on child development.
publishDate 2015
dc.date.none.fl_str_mv 2015
2023
2023
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10230/58349
http://dx.doi.org/10.5271/sjweh.3500
url http://hdl.handle.net/10230/58349
http://dx.doi.org/10.5271/sjweh.3500
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Scandinavian Journal of Work, Environment & Health. 2015 Jul;41(4):384-96
info:eu-repo/grantAgreement/EC/FP7/241604
info:eu-repo/grantAgreement/EC/FP7/226285
dc.rights.none.fl_str_mv This work is licensed under a Creative Commons Attribution 4.0 International License.
http://creativecommons.org/licenses/by/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv This work is licensed under a Creative Commons Attribution 4.0 International License.
http://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv NOROSH
publisher.none.fl_str_mv NOROSH
dc.source.none.fl_str_mv reponame:Repositorio Digital de la UPF
instname:Universitat Pompeu Fabra
instname_str Universitat Pompeu Fabra
reponame_str Repositorio Digital de la UPF
collection Repositorio Digital de la UPF
repository.name.fl_str_mv
repository.mail.fl_str_mv
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