Degradable Poly(ester amide)s for biomedical aplications

Poly(ester amide)s are an emerging group of biodegradable polymers that may cover both commodity and speciality applications. These polymers have ester and amide groups on their chemical structure which are of a degradable character and provide good thermal and mechanical properties. In this sense,...

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Autores: Rodríguez Galán, Rafael Alfonso, Franco García, María Lourdes|||0000-0001-5968-285X, Puiggalí Bellalta, Jordi|||0000-0002-0640-4474
Tipo de recurso: artículo
Fecha de publicación:2010
País:España
Institución:Universitat Politècnica de Catalunya (UPC)
Repositorio:UPCommons. Portal del coneixement obert de la UPC
Idioma:inglés
OAI Identifier:oai:upcommons.upc.edu:2117/11653
Acceso en línea:https://hdl.handle.net/2117/11653
https://dx.doi.org/10.3390/polym3010065
Access Level:acceso abierto
Palabra clave:Polymers
Biodegradation
Polyesters.
Poliester
Biodegradació
Àrees temàtiques de la UPC::Enginyeria química
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spelling Degradable Poly(ester amide)s for biomedical aplicationsRodríguez Galán, Rafael AlfonsoFranco García, María Lourdes|||0000-0001-5968-285XPuiggalí Bellalta, Jordi|||0000-0002-0640-4474PolymersBiodegradationPolyesters.PoliesterBiodegradacióÀrees temàtiques de la UPC::Enginyeria químicaPoly(ester amide)s are an emerging group of biodegradable polymers that may cover both commodity and speciality applications. These polymers have ester and amide groups on their chemical structure which are of a degradable character and provide good thermal and mechanical properties. In this sense, the strong hydrogen‑bonding interactions between amide groups may counter some typical weaknesses of aliphatic polyesters like for example poly(e-caprolactone). Poly(ester amide)s can be prepared from different monomers and following different synthetic methodologies which lead to polymers with random, blocky and ordered microstructures. Properties like hydrophilic/hydrophobic ratio and biodegradability can easily be tuned. During the last decade a great effort has been made to get functionalized poly(ester amide)s by incorporation of a-amino acids with hydroxyl, carboxyl and amine pendant groups and also by incorporation of carbon-carbon double bonds in both the polymer main chain and the side groups. Specific applications of these materials in the biomedical field are just being developed and are reviewed in this work (e.g., controlled drug delivery systems, hydrogels, tissue engineering and other uses like adhesives and smart materials) together with the main families of functionalized poly(ester amide)s that have been developed to date.Peer Reviewed20102010-12-2720112011-03-04journal articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/2117/11653https://dx.doi.org/10.3390/polym3010065reponame:UPCommons. Portal del coneixement obert de la UPCinstname:Universitat Politècnica de Catalunya (UPC)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2Attribution-NonCommercial-NoDerivs 3.0 Spainhttp://creativecommons.org/licenses/by-nc-nd/3.0/es/info:eu-repo/semantics/openAccessoai:upcommons.upc.edu:2117/116532026-05-27T15:37:01Z
dc.title.none.fl_str_mv Degradable Poly(ester amide)s for biomedical aplications
title Degradable Poly(ester amide)s for biomedical aplications
spellingShingle Degradable Poly(ester amide)s for biomedical aplications
Rodríguez Galán, Rafael Alfonso
Polymers
Biodegradation
Polyesters.
Poliester
Biodegradació
Àrees temàtiques de la UPC::Enginyeria química
title_short Degradable Poly(ester amide)s for biomedical aplications
title_full Degradable Poly(ester amide)s for biomedical aplications
title_fullStr Degradable Poly(ester amide)s for biomedical aplications
title_full_unstemmed Degradable Poly(ester amide)s for biomedical aplications
title_sort Degradable Poly(ester amide)s for biomedical aplications
dc.creator.none.fl_str_mv Rodríguez Galán, Rafael Alfonso
Franco García, María Lourdes|||0000-0001-5968-285X
Puiggalí Bellalta, Jordi|||0000-0002-0640-4474
author Rodríguez Galán, Rafael Alfonso
author_facet Rodríguez Galán, Rafael Alfonso
Franco García, María Lourdes|||0000-0001-5968-285X
Puiggalí Bellalta, Jordi|||0000-0002-0640-4474
author_role author
author2 Franco García, María Lourdes|||0000-0001-5968-285X
Puiggalí Bellalta, Jordi|||0000-0002-0640-4474
author2_role author
author
dc.subject.none.fl_str_mv Polymers
Biodegradation
Polyesters.
Poliester
Biodegradació
Àrees temàtiques de la UPC::Enginyeria química
topic Polymers
Biodegradation
Polyesters.
Poliester
Biodegradació
Àrees temàtiques de la UPC::Enginyeria química
description Poly(ester amide)s are an emerging group of biodegradable polymers that may cover both commodity and speciality applications. These polymers have ester and amide groups on their chemical structure which are of a degradable character and provide good thermal and mechanical properties. In this sense, the strong hydrogen‑bonding interactions between amide groups may counter some typical weaknesses of aliphatic polyesters like for example poly(e-caprolactone). Poly(ester amide)s can be prepared from different monomers and following different synthetic methodologies which lead to polymers with random, blocky and ordered microstructures. Properties like hydrophilic/hydrophobic ratio and biodegradability can easily be tuned. During the last decade a great effort has been made to get functionalized poly(ester amide)s by incorporation of a-amino acids with hydroxyl, carboxyl and amine pendant groups and also by incorporation of carbon-carbon double bonds in both the polymer main chain and the side groups. Specific applications of these materials in the biomedical field are just being developed and are reviewed in this work (e.g., controlled drug delivery systems, hydrogels, tissue engineering and other uses like adhesives and smart materials) together with the main families of functionalized poly(ester amide)s that have been developed to date.
publishDate 2010
dc.date.none.fl_str_mv 2010
2010-12-27
2011
2011-03-04
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://hdl.handle.net/2117/11653
https://dx.doi.org/10.3390/polym3010065
url https://hdl.handle.net/2117/11653
https://dx.doi.org/10.3390/polym3010065
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial-NoDerivs 3.0 Spain
http://creativecommons.org/licenses/by-nc-nd/3.0/es/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial-NoDerivs 3.0 Spain
http://creativecommons.org/licenses/by-nc-nd/3.0/es/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:UPCommons. Portal del coneixement obert de la UPC
instname:Universitat Politècnica de Catalunya (UPC)
instname_str Universitat Politècnica de Catalunya (UPC)
reponame_str UPCommons. Portal del coneixement obert de la UPC
collection UPCommons. Portal del coneixement obert de la UPC
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