SEOM-GEMCAD-TTD clinical guidelines for localized rectal cancer (2021)

The management of localized rectal cancer requires a multidisciplinary approach to optimize outcomes, reduce morbidity and prevent under or overtreatments. While early stages may obtain benefit of local resections without any additional therapies, locally advanced rectal cancer becomes a challenge d...

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Bibliographic Details
Authors: Capdevila, Jaume, Gómez, Ma Auxiliadora, Guillot, Mónica, Paéz, David, Pericay, Carles, Safont, Maria José, Tarazona, Noelia, Vera, Ruth, Vidal Barrull, Joana, Sastre, Javier
Format: article
Status:Published version
Publication Date:2022
Country:España
Institution:Universitat Pompeu Fabra
Repository:Repositorio Digital de la UPF
OAI Identifier:oai:repositori.upf.edu:10230/53939
Online Access:http://hdl.handle.net/10230/53939
http://dx.doi.org/10.1007/s12094-022-02816-9
Access Level:Open access
Keyword:Guideline
Rectal cancer
Total neoadjuvant therapy
Description
Summary:The management of localized rectal cancer requires a multidisciplinary approach to optimize outcomes, reduce morbidity and prevent under or overtreatments. While early stages may obtain benefit of local resections without any additional therapies, locally advanced rectal cancer becomes a challenge defining the better sequential strategy of surgery, radiotherapy and chemotherapy. The latest results of international phase III studies have positioned the total neoadjuvant therapy as a potential new standard of care in high risk rectal cancers, however, the best schedule is still not well defined.