Tumor Functional Heterogeneity Unraveled by scRNA-seq Technologies

Effective cancer treatment has been precluded by the presence of various forms of intratumoral complexity that drive treatment resistance and metastasis. Recent single-cell sequencing technologies are significantly facilitating the characterization of tumor internal architecture during disease progr...

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Detalhes bibliográficos
Autores: González Silva, Laura, Quevedo Palacio, Laura, Varela Egocheaga, Ignacio|||0000-0002-0969-506X
Formato: artículo
Fecha de publicación:2020
País:España
Recursos:Universidad de Cantabria (UC)
Repositorio:UCrea Repositorio Abierto de la Universidad de Cantabria
Idioma:inglés
OAI Identifier:oai:repositorio.unican.es:10902/20553
Acesso em linha:http://hdl.handle.net/10902/20553
Access Level:acceso abierto
Palavra-chave:Cancer Functional Heterogeneity
Intratumor Heterogeneity
Single-Cell Sequencing
Tumor Microenvironment
Liquid Biopsy
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spelling Tumor Functional Heterogeneity Unraveled by scRNA-seq TechnologiesGonzález Silva, LauraQuevedo Palacio, LauraVarela Egocheaga, Ignacio|||0000-0002-0969-506XCancer Functional HeterogeneityIntratumor HeterogeneitySingle-Cell SequencingTumor MicroenvironmentLiquid BiopsyEffective cancer treatment has been precluded by the presence of various forms of intratumoral complexity that drive treatment resistance and metastasis. Recent single-cell sequencing technologies are significantly facilitating the characterization of tumor internal architecture during disease progression. New applications and advances occurring at a fast pace predict an imminent broad application of these technologies in many research areas. As occurred with next-generation sequencing (NGS) technologies, once applied to clinical samples across tumor types, single-cell sequencing technologies could trigger an exponential increase in knowledge of the molecular pathways involved in cancer progression and contribute to the improvement of cancer treatment.Cell PressUniversidad de Cantabria20202020-01-03journal articlehttp://purl.org/coar/resource_type/c_6501NAhttp://purl.org/coar/version/c_be7fb7dd8ff6fe43info:eu-repo/semantics/articlehttp://hdl.handle.net/10902/20553Trends Cancer . 2020 Jan;6(1):13-19reponame:UCrea Repositorio Abierto de la Universidad de Cantabriainstname:Universidad de Cantabria (UC)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2Attribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:repositorio.unican.es:10902/205532026-06-02T12:39:31Z
dc.title.none.fl_str_mv Tumor Functional Heterogeneity Unraveled by scRNA-seq Technologies
title Tumor Functional Heterogeneity Unraveled by scRNA-seq Technologies
spellingShingle Tumor Functional Heterogeneity Unraveled by scRNA-seq Technologies
González Silva, Laura
Cancer Functional Heterogeneity
Intratumor Heterogeneity
Single-Cell Sequencing
Tumor Microenvironment
Liquid Biopsy
title_short Tumor Functional Heterogeneity Unraveled by scRNA-seq Technologies
title_full Tumor Functional Heterogeneity Unraveled by scRNA-seq Technologies
title_fullStr Tumor Functional Heterogeneity Unraveled by scRNA-seq Technologies
title_full_unstemmed Tumor Functional Heterogeneity Unraveled by scRNA-seq Technologies
title_sort Tumor Functional Heterogeneity Unraveled by scRNA-seq Technologies
dc.creator.none.fl_str_mv González Silva, Laura
Quevedo Palacio, Laura
Varela Egocheaga, Ignacio|||0000-0002-0969-506X
author González Silva, Laura
author_facet González Silva, Laura
Quevedo Palacio, Laura
Varela Egocheaga, Ignacio|||0000-0002-0969-506X
author_role author
author2 Quevedo Palacio, Laura
Varela Egocheaga, Ignacio|||0000-0002-0969-506X
author2_role author
author
dc.contributor.none.fl_str_mv Universidad de Cantabria
dc.subject.none.fl_str_mv Cancer Functional Heterogeneity
Intratumor Heterogeneity
Single-Cell Sequencing
Tumor Microenvironment
Liquid Biopsy
topic Cancer Functional Heterogeneity
Intratumor Heterogeneity
Single-Cell Sequencing
Tumor Microenvironment
Liquid Biopsy
description Effective cancer treatment has been precluded by the presence of various forms of intratumoral complexity that drive treatment resistance and metastasis. Recent single-cell sequencing technologies are significantly facilitating the characterization of tumor internal architecture during disease progression. New applications and advances occurring at a fast pace predict an imminent broad application of these technologies in many research areas. As occurred with next-generation sequencing (NGS) technologies, once applied to clinical samples across tumor types, single-cell sequencing technologies could trigger an exponential increase in knowledge of the molecular pathways involved in cancer progression and contribute to the improvement of cancer treatment.
publishDate 2020
dc.date.none.fl_str_mv 2020
2020-01-03
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
NA
http://purl.org/coar/version/c_be7fb7dd8ff6fe43
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv http://hdl.handle.net/10902/20553
url http://hdl.handle.net/10902/20553
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Cell Press
publisher.none.fl_str_mv Cell Press
dc.source.none.fl_str_mv Trends Cancer . 2020 Jan;6(1):13-19
reponame:UCrea Repositorio Abierto de la Universidad de Cantabria
instname:Universidad de Cantabria (UC)
instname_str Universidad de Cantabria (UC)
reponame_str UCrea Repositorio Abierto de la Universidad de Cantabria
collection UCrea Repositorio Abierto de la Universidad de Cantabria
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15.300719

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