Effectiveness of the early intervention service for first-episode psychosis in Navarra (PEPsNa): broadening the scope of outcome measures

Background This study compares the effectiveness of a new early intervention service for firstepisode psychosis (FEP) in patients under conventional treatment. Six primary and 10 secondary outcome measures are used to better characterize the comparative effectiveness between two FEP groups. Methods...

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Autores: García de Jalón, Elena, Ariz, Mari Cruz, Aquerreta, Ainhoa, Aranguren Conde, Lidia, Gutiérrez, Gerardo, Corrales, Asier, Sánchez Torres, Ana María, Gil Berrozpe, Gustavo José, Peralta Martín, Víctor, Cuesta, Manuel J., PEPsNa Group
Formato: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2023
País:España
Recursos:Universidad Pública de Navarra
Repositorio:Academica-e. Repositorio Institucional de la Universidad Pública de Navarra
OAI Identifier:oai:academica-e.unavarra.es:2454/53694
Acesso em linha:https://hdl.handle.net/2454/53694
Access Level:acceso abierto
Palavra-chave:First-episode psychosis
Schizophrenia
Early intervention service
Recovery
Effectiveness
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spelling Effectiveness of the early intervention service for first-episode psychosis in Navarra (PEPsNa): broadening the scope of outcome measuresGarcía de Jalón, ElenaAriz, Mari CruzAquerreta, AinhoaAranguren Conde, LidiaGutiérrez, GerardoCorrales, AsierSánchez Torres, Ana MaríaGil Berrozpe, Gustavo JoséPeralta Martín, VíctorCuesta, Manuel J.PEPsNa GroupFirst-episode psychosisSchizophreniaEarly intervention serviceRecoveryEffectivenessBackground This study compares the effectiveness of a new early intervention service for firstepisode psychosis (FEP) in patients under conventional treatment. Six primary and 10 secondary outcome measures are used to better characterize the comparative effectiveness between two FEP groups. Methods This study plans to enroll 250 patients aged 15-55 years with FEP from all inpatient and outpatient mental health services and primary health care from January 2020 until December 2022. The control group will be composed of 130 FEP patients treated in mental health centers in the 2 years prior to the start of PEPsNa (Programa de Primeros Episodios de Psicosis de Navarra). The primary outcome measures are symptomatic remission, functional recovery, personal recovery, cognitive performance, functional capacity in real-world settings, and costs. The secondary outcome measures are duration of untreated psychosis, substance abuse rate, antipsychotic monotherapy, minimal effective dose of antipsychotic drugs, therapeutic alliance, drop-out rate, number of relapses, global mortality and suicidality, resource use, and general satisfaction in the program. Discussion This study arises from the growing need to broaden the scope of outcome measures in FEP patients and to account for unmet needs of recovery for FEPs. It aims to contribute in the dissemination of the NAVIGATE model in Europe and to provide new evidence of the effectiveness of early intervention services for stakeholders of the National Health Service.This study was funded by a grant from the Carlos III Health Institute of the Ministry of Science and Innovation of the Government of Spain (PI19/01698).ElsevierCiencias de la SaludOsasun Zientziak2023info:eu-repo/semantics/articleinfo:eu-repo/semantics/acceptedVersionapplication/pdfhttps://hdl.handle.net/2454/53694reponame:Academica-e. Repositorio Institucional de la Universidad Pública de Navarrainstname:Universidad Pública de NavarraInglésinfo:eu-repo/grantAgreement/ISCIII/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020 (ISCIII)/PI19%2F01698© 2022 Sociedad Espanola de Psiquiatría y Salud Mental (SEPSM). Published by Elsevier España, S.L.U. This manuscript version is made available under the CC-BY-NC-ND 4.0.https://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:academica-e.unavarra.es:2454/536942026-06-17T12:41:47Z
dc.title.none.fl_str_mv Effectiveness of the early intervention service for first-episode psychosis in Navarra (PEPsNa): broadening the scope of outcome measures
title Effectiveness of the early intervention service for first-episode psychosis in Navarra (PEPsNa): broadening the scope of outcome measures
spellingShingle Effectiveness of the early intervention service for first-episode psychosis in Navarra (PEPsNa): broadening the scope of outcome measures
García de Jalón, Elena
First-episode psychosis
Schizophrenia
Early intervention service
Recovery
Effectiveness
title_short Effectiveness of the early intervention service for first-episode psychosis in Navarra (PEPsNa): broadening the scope of outcome measures
title_full Effectiveness of the early intervention service for first-episode psychosis in Navarra (PEPsNa): broadening the scope of outcome measures
title_fullStr Effectiveness of the early intervention service for first-episode psychosis in Navarra (PEPsNa): broadening the scope of outcome measures
title_full_unstemmed Effectiveness of the early intervention service for first-episode psychosis in Navarra (PEPsNa): broadening the scope of outcome measures
title_sort Effectiveness of the early intervention service for first-episode psychosis in Navarra (PEPsNa): broadening the scope of outcome measures
dc.creator.none.fl_str_mv García de Jalón, Elena
Ariz, Mari Cruz
Aquerreta, Ainhoa
Aranguren Conde, Lidia
Gutiérrez, Gerardo
Corrales, Asier
Sánchez Torres, Ana María
Gil Berrozpe, Gustavo José
Peralta Martín, Víctor
Cuesta, Manuel J.
PEPsNa Group
author García de Jalón, Elena
author_facet García de Jalón, Elena
Ariz, Mari Cruz
Aquerreta, Ainhoa
Aranguren Conde, Lidia
Gutiérrez, Gerardo
Corrales, Asier
Sánchez Torres, Ana María
Gil Berrozpe, Gustavo José
Peralta Martín, Víctor
Cuesta, Manuel J.
PEPsNa Group
author_role author
author2 Ariz, Mari Cruz
Aquerreta, Ainhoa
Aranguren Conde, Lidia
Gutiérrez, Gerardo
Corrales, Asier
Sánchez Torres, Ana María
Gil Berrozpe, Gustavo José
Peralta Martín, Víctor
Cuesta, Manuel J.
PEPsNa Group
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Ciencias de la Salud
Osasun Zientziak
dc.subject.none.fl_str_mv First-episode psychosis
Schizophrenia
Early intervention service
Recovery
Effectiveness
topic First-episode psychosis
Schizophrenia
Early intervention service
Recovery
Effectiveness
description Background This study compares the effectiveness of a new early intervention service for firstepisode psychosis (FEP) in patients under conventional treatment. Six primary and 10 secondary outcome measures are used to better characterize the comparative effectiveness between two FEP groups. Methods This study plans to enroll 250 patients aged 15-55 years with FEP from all inpatient and outpatient mental health services and primary health care from January 2020 until December 2022. The control group will be composed of 130 FEP patients treated in mental health centers in the 2 years prior to the start of PEPsNa (Programa de Primeros Episodios de Psicosis de Navarra). The primary outcome measures are symptomatic remission, functional recovery, personal recovery, cognitive performance, functional capacity in real-world settings, and costs. The secondary outcome measures are duration of untreated psychosis, substance abuse rate, antipsychotic monotherapy, minimal effective dose of antipsychotic drugs, therapeutic alliance, drop-out rate, number of relapses, global mortality and suicidality, resource use, and general satisfaction in the program. Discussion This study arises from the growing need to broaden the scope of outcome measures in FEP patients and to account for unmet needs of recovery for FEPs. It aims to contribute in the dissemination of the NAVIGATE model in Europe and to provide new evidence of the effectiveness of early intervention services for stakeholders of the National Health Service.
publishDate 2023
dc.date.none.fl_str_mv 2023
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/acceptedVersion
format article
status_str acceptedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2454/53694
url https://hdl.handle.net/2454/53694
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv info:eu-repo/grantAgreement/ISCIII/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020 (ISCIII)/PI19%2F01698
dc.rights.none.fl_str_mv https://creativecommons.org/licenses/by-nc-nd/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Academica-e. Repositorio Institucional de la Universidad Pública de Navarra
instname:Universidad Pública de Navarra
instname_str Universidad Pública de Navarra
reponame_str Academica-e. Repositorio Institucional de la Universidad Pública de Navarra
collection Academica-e. Repositorio Institucional de la Universidad Pública de Navarra
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15.812429

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